Problems and prerequisites for determining the legal regime preimplantation genetic diagnosis in Russian legislation

Human Embryo ◽

Legal Status ◽

Genetic Diagnosis ◽

Legal Regime ◽

Сurrent problems and prerequisites for the formation of the legal regime of pre-implantation genetic diagnosis (PGD) are considered in Russian legislation with account the existing approaches to determining the legal status of a “pre-implantation” embryo obtained in the framework of the in vitro fertilization procedure (IVF) are discussed. The authors substantiates the conclusion that it is necessary to legally determine PGD as one of the stages of using IVF, as well as establishing generally binding requirements for the procedure, conditions and features of this diagnosis, taking into account the need to minimize the damage caused to the human embryo.

In Vitro Fertilization and the Embryonic Revolution

Handbook of Research on Technoethics ◽

10.4018/978-1-60566-022-6.ch039 ◽

2009 ◽

pp. 609-622

Author(s):

D. Gareth Jones

Keyword(s):

Stem Cells ◽

In Vitro Fertilization ◽

Human Embryo ◽

Human Life ◽

Genetic Diagnosis ◽

Embryonic Stem ◽

Reproductive Technologies ◽

Vitro Fertilization ◽

Human Embryology

The advent of in vitro fertilization (IVF) marked a watershed in the scientific understanding of the human embryo. This, in turn, led to a renaissance of human embryology, accompanied by the ability to manipulate the human embryo in the laboratory. This ability has resulted in yet further developments: refinements of IVF itself, preimplantation genetic diagnosis, the derivation and extraction of embryonic stem cells, and even various forms of cloning. There are immense social and scientific pressures to utilize the artificial reproductive technologies in ways that have little or no connection with overcoming infertility. As the original clinical goals of IVF have undergone transformation ethical concerns have escalated, so much so that they are condemned by some as illustrations of ‘playing God’, while any babies born via some of these procedures are labelled as ‘designer babies’. Both terms reflect the fear and repugnance felt by some at the interference with the earliest stages of human life by the artificial reproductive technologies. It is at these points that bioethical analyses have an important contribution to make.

In vitro fertilization plus preimplantation genetic diagnosis in patients with recurrent miscarriage: an analysis of chromosome abnormalities in human preimplantation embryos

10.1016/s0015-0282(99)00143-0 ◽

1999 ◽

Vol 71 (6) ◽

pp. 1033-1039 ◽

Cited By ~ 88

Author(s):

Antonio Pellicer ◽

Carmen Rubio ◽

Francesca Vidal ◽

Yolanda Mı́nguez ◽

Carles Giménez ◽

...

Keyword(s):

In Vitro Fertilization ◽

Recurrent Miscarriage ◽

Genetic Diagnosis ◽

Chromosome Abnormalities ◽

Preimplantation Embryos ◽

Vitro Fertilization ◽

Human Preimplantation Embryos

Preimplantation genetic diagnosis (PGD) by fluorescence in situ hybridization (FISH) analysis for aneuploidy on more than one hundred in vitro fertilization (IVF) patients: The influence of patient age on pregnancy outcomes

10.1016/j.fertnstert.2004.07.647 ◽

2004 ◽

Vol 82 ◽

pp. S243

Author(s):

W.G. Kearns ◽

R. Pen ◽

K.S. Richter ◽

E.A. Widra

Keyword(s):

In Situ Hybridization ◽

In Vitro Fertilization ◽

Fluorescence In Situ Hybridization ◽

Pregnancy Outcomes ◽

Genetic Diagnosis ◽

Fish Analysis ◽

First successful pregnancy outcome after preimplantation genetic diagnosis for aneuploidy screening in embryos generated from natural-cycle in vitro fertilization combined with an in vitro maturation procedure

10.1016/j.fertnstert.2005.10.066 ◽

2006 ◽

Vol 85 (5) ◽

pp. 1510.e9-1510.e11 ◽

Cited By ~ 13

Author(s):

Asangla Ao ◽

Shaoguang Jin ◽

Durga Rao ◽

Weon-Young Son ◽

Ri-Cheng Chian ◽

...

Keyword(s):

In Vitro Fertilization ◽

Pregnancy Outcome ◽

In Vitro Maturation ◽

Genetic Diagnosis ◽

Natural Cycle ◽

Successful Pregnancy ◽

Aneuploidy Screening ◽

Profound teratospermia does not influence sex chromosomal aneuploidy rate in in vitro fertilization–preimplantation genetic diagnosis cycles

10.1016/j.fertnstert.2009.07.1006 ◽

2010 ◽

Vol 93 (2) ◽

pp. 666-668 ◽

Cited By ~ 1

Author(s):

Molina B. Dayal ◽

Paul R. Gindoff ◽

Shvetha Zarek ◽

Douglas Peak ◽

Anil Dubey ◽

...

Keyword(s):

In Vitro Fertilization ◽

Genetic Diagnosis ◽

Vitro Fertilization ◽

Aneuploidy Rate ◽

Chromosomal Aneuploidy

Preimplantation genetic diagnosis for the treatment of failed in vitro fertilization–embryo transfer and habitual abortion

10.1016/j.fertnstert.2003.10.028 ◽

2004 ◽

Vol 81 (5) ◽

pp. 1302-1307 ◽

Cited By ~ 33

Author(s):

Martin Wilding ◽

Robert Forman ◽

George Hogewind ◽

Loredana Di Matteo ◽

Fulvio Zullo ◽

...

Keyword(s):

In Vitro Fertilization ◽

Embryo Transfer ◽

Genetic Diagnosis ◽

Vitro Fertilization ◽

Habitual Abortion

Gender does not impact the developmental rate of in vitro fertilization-derived human embryos as confirmed by day 3 blastomere biopsy and preimplantation genetic diagnosis (PGD)

10.1016/j.fertnstert.2004.02.042 ◽

2004 ◽

Vol 81 ◽

pp. 17-18

Author(s):

K. Miller ◽

K. Elkind-Hirsch ◽

S. Ross ◽

B. Levy ◽

R.T. Scott

Keyword(s):

In Vitro Fertilization ◽

Genetic Diagnosis ◽

Developmental Rate ◽

Human Embryos ◽

Vitro Fertilization ◽

Blastomere Biopsy

Clinical Management of in Vitro Fertilization with Preimplantation Genetic Diagnosis

Seminars in Reproductive Medicine ◽

10.1055/s-0032-1313910 ◽

2012 ◽

Vol 30 (04) ◽

pp. 309-322 ◽

Cited By ~ 14

Author(s):

Ilan Tur-Kaspa

Keyword(s):

In Vitro Fertilization ◽

Clinical Management ◽

Genetic Diagnosis ◽

Reprogenetic Technologies

10.1093/med/9780190460204.003.0002 ◽

2016 ◽

Author(s):

Inmaculada de Melo-Martín

Keyword(s):

In Vitro Fertilization ◽

Gene Editing ◽

Genetic Diagnosis ◽

Vitro Fertilization ◽

Technological Advances ◽

Mitochondrial Transfer

This chapter offers a brief description of the main reprogenetic technologies in use today as well as some of the most significant ones being developed. Because of their relevance in the field, particular attention is given to in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD). The chapter discusses the differences between somatic and germline modifications, the most common uses of reprogenetic technologies today, and some possible and likely future uses. It also includes a description of recent technological advances such as mitochondrial transfer and gene editing techniques.