scholarly journals SUBCLINICAL SYSTOLIC DYSFUNCTION OF THE LEFT VENTRICLE IN PREECLAMPTIC WOMEN WITHOUT PROTEINURIA. THE POSSIBILITIES OF ECHOCARDIOGRAPHY IN EARLY DIAGNOSIS

2017 ◽  
pp. 94-97
Author(s):  
D. A. Doroshenko ◽  
A. R. Zubarev ◽  
O. B. Lapochkina
Keyword(s):  
Left Ventricle ◽  
Arterial Hypertension ◽  
Pregnant Women ◽  
Left Ventricular Dysfunction ◽  
Speckle Tracking ◽  
Ventricular Dysfunction ◽  
Speckle Tracking Echocardiography ◽  
Systolic Dysfunction ◽  
Clinical Manifestations ◽  
Left Ventricular

The article presents the main pathophysiological mechanisms associated with the development of complications of pregnancy against the background of arterial hypertension in patients without clinical manifestations of left ventricular dysfunction, the possibilities of speckle tracking of echocardiography in revealing latent systolic dysfunction of the left ventricle in pregnant women on the background of preeclampsia not accompanied by proteinuria are shown.Goal. To identify early markers of left ventricular systolic dysfunction in pregnant women with preeclampsia without proteinuria according to speckle tracking echocardiography.Material and methods. 100 pregnant women with hypertension and a gestation period of 29–40 weeks are divided into 2 groups: 1 st group – 50 patients without an arterial hypertension in the anamnesis, 2 nd group – 50 patients with an arterial hypertension in the anamnesis (without the proteinuria during pregnancy). For all patients, echocardiography with evaluation of cardiomyocyte function by speckle-tracking was performed on ultrasonic scanners Aplio ™ 500 and Aplio ™ Artida from Toshiba.Results. Ejection fraction of the left ventricle in the groups was not significantly different, while the longitudinal, radial and circular deformation parameters differed between the groups, with the lowest values characterizing the global longitudinal deformation.Conclusions. In assessing the function of the left ventricle in pregnant women with preeclampsia without diurnal proteinuria, it is not enough to focus on traditional parameters, shifting the emphasis towards derivatives of force, speed and time. Study of myocardium with the help of speckle tracking echocardiography promotes the detection of subclinical left ventricular dysfunction in patients with arterial hypertension without daily proteinuria. 

scholarly journals Value of speckle tracking echocardiography for detection of clinically silent left ventricular dysfunction in patients with β-thalassemia

Hematology ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 554-558 ◽  
Author(s):  
Mozhgan Parsaee ◽  
Sedigheh Saedi ◽  
Pegah Joghataei ◽  
Azita Azarkeivan ◽  
Zahra Alizadeh Sani
Keyword(s):  
Left Ventricular Dysfunction ◽  
Speckle Tracking ◽  
Ventricular Dysfunction ◽  
Speckle Tracking Echocardiography ◽  
Left Ventricular

Speckle tracking echocardiography for the evaluation of left ventricular function in children with systemic lupus erythematosus

Lupus ◽  
2020 ◽  
Vol 29 (11) ◽  
pp. 1449-1455
Author(s):  
Mai Emara ◽  
Maher Abdel Hafez ◽  
Aml El-Bendary ◽  
Osama El Razaky
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Natriuretic Peptide ◽  
Left Ventricular Dysfunction ◽  
Lupus Erythematosus ◽  
Speckle Tracking ◽  
Ventricular Dysfunction ◽  
Speckle Tracking Echocardiography ◽  
Left Ventricular ◽  
Systemic Lupus

Background Many studies in adult patients with systemic lupus erythematosus (SLE) have demonstrated that myocardial dysfunction was significantly associated with enhanced disease activity. However, similar studies in paediatric patients with SLE are limited. The aim of this study was to evaluate the role of speckle tracking echocardiography (STE) to detect left ventricular dysfunction in children with active and inactive SLE. Methods This prospective case–control study was carried out on 50 children with SLE. Thirty healthy age- and sex-matched children comprised the control group. The patients were further subdivided into two subgroups: active SLE and inactive SLE. Laboratory investigations undertaken included complete blood count, renal function, C3, C4, ANA, anti-dsDNA and serum N-terminal pro-B type natriuretic peptide. Echocardiographic examinations were performed on all children and included conventional echocardiography, tissue Doppler imaging (TDI) and two- and three-dimensional STE. Results There was no statistically significant difference in N-terminal pro B natriuretic peptide between the studied groups. The myocardial performance index by TDI was statistically significantly higher in SLE patients compared to controls. STE parameters were statistically significantly lower in SLE patients compared to controls. There was no correlation between STE parameters and disease activity. Conclusions STE could be a promising technique in the early detection of subclinical left ventricular dysfunction in children with SLE.

Evaluation of anthracycline incuced cardiotoxicity by speckle tracking echocardiography.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e11585-e11585
Author(s):  
Atalay Dogru ◽  
Devrim Cabuk ◽  
Tayfun Sahin ◽  
Ilhan Dolasik ◽  
Kazim Uygun
Keyword(s):  
Left Ventricular Dysfunction ◽  
Speckle Tracking ◽  
Ventricular Dysfunction ◽  
Speckle Tracking Echocardiography ◽  
Systolic Function ◽  
Left Ventricular ◽  
High Dose ◽  
Systolic Strain ◽  
Peak Systolic Strain ◽  
Global Peak

e11585 Background: Anthracyclines have been widely used in the treatment of solid and hematologic malignancies. Cardiotoxicity is the most serious adverse effect that limits anthracycline treatment. Cardiotoxicity is classified by time of onset as acute, subacute and chronic. Conventional echocardiography is not sensitive enough for early detection of cardiotoxicity. In this study we aimed to evaluate anthracycline induced cardiac toxicity by speckle tracking echocardiography (STE) before left ventricular dysfunction occurs. Methods: The study included newly diagnosed breast cancer (BC) and lymphoma patients (pts) who were treated with an anthracycline containing chemotherapy (CT) regimen. They had examination with conventional echocardiyography, STE before and after anthracycline treatment. Longitudinal strain values were assessed by automated function image (AFI). Results: Thirty five pts with BC and 15 pts with lymphoma were included in the study. Ejection fraction (EF) and fractional shortening values were decreased in lymphoma pts receiving high dose anthracycline treatment (346 mg/m2) compared to BC pts receiving low dose (168 mg/m2) anthracycline. There was statistically significant increase in myocardial performance index in both groups after anthracycline CT (p=0.001 and p=0.004 for BC and lymphoma group respectively). In STE measurements, apical long axis, apikal 4 chamber and global peak systolic strain showed significant reduction in lymphoma group who had a post-therapy EF <55% (p=0.002, p=0.041, and p=0.004, respectively). Apical long axis and global peak systolic strain were also significantly decreased among the lymphoma pts with normal systolic function after CT (p=0.01 and p=0.05, respectively). Conclusions: STE can display the effect of anthracycline induced cardiotoxicity early before left ventricular dysfunction occurs. Larger prospective studies are needed to verify these data and direct the treatment of pts receiving anthracycline.

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