scholarly journals CYTOTOXIC EFFECT OF SILVER NANOPARTICLES ON COLORECTAL ADENOCARCINOMA CELL LINE

2021 ◽  
Vol 44 (2) ◽  
pp. 587-597
Author(s):  
Alaa Salman ◽  
Chadi Soukkarieh ◽  
Samar Alzeer
Keyword(s):  
Silver Nanoparticles ◽  
Cell Line ◽  
Cytotoxic Effect ◽  
Colorectal Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell

1,2-Dihydrochromeno[2,3-c]pyrrol-3-one Derivatives: Synthesis and HPLC-ECD Analysis

Synlett ◽  
2019 ◽  
Vol 30 (07) ◽  
pp. 799-802 ◽  
Author(s):  
László Tóth ◽  
Attila Kiss-Szikszai ◽  
Gábor Vasvári ◽  
Ferenc Fenyvesi ◽  
Miklós Vecsernyés ◽  
...  
Keyword(s):  
Double Bond ◽  
Cell Line ◽  
Antiproliferative Activity ◽  
Reductive Amination ◽  
Colorectal Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Configurational Assignment ◽  
Stereogenic Center

Ethyl-3-formyl-6-methoxy-(2H)-chromene-2-carboxylate was transformed to N-substituted 1,2-dihydrochromeno[2,3-c]pyrrol-3-ones in a domino reductive amination–lactamization reaction. Isomerization of the double bond and the inherently labile stereogenic center was studied, and HPLC-ECD analysis of a chiral 1,2-dihydrochromeno[2,3-c]pyrrol-3(3aH)-one derivative aided by TDDFT-ECD calculation allowed configurational assignment of the separated enantiomers. Antiproliferative activity of the products was demonstrated on the CaCo-2 human epithelial colorectal adenocarcinoma cell line.

Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line

2005 ◽  
Vol 118 (3) ◽  
pp. 616-627 ◽  
Author(s):  
Michael L. Roberts ◽  
Konstantinos G. Drosopoulos ◽  
Ioannis Vasileiou ◽  
Mona Stricker ◽  
Era Taoufik ◽  
...  
Keyword(s):  
Cell Line ◽  
Microarray Analysis ◽  
Colorectal Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Differential Transformation ◽  
Ras Oncogenes
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