ANTENATAL CORTICOSTEROID THERAPY: A COMPARATIVE STUDY OF DEXAMETHASONE AND BETAMETHASONE EFFECTS ON FETAL DOPPLER INDICES

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
marwa elmorsy ◽  
Seham El Berry ◽  
Ayman shedid ◽  
Sara Mostafa
Keyword(s):  
Comparative Study ◽  
Corticosteroid Therapy ◽  
Antenatal Corticosteroid ◽  
Fetal Doppler ◽  
Doppler Indices

Direct intramuscular fetal or maternal antenatal corticosteroid therapy: short-time effects on fetal behavior and oxygenation: a comparative study

2015 ◽  
Vol 29 (19) ◽  
pp. 3213-3217 ◽  
Author(s):  
Ivana Babović ◽  
Zoran Radojičić ◽  
Snežana Plešinac ◽  
Biljana Kastratović Kotlica ◽  
Radmila Sparić
Keyword(s):  
Comparative Study ◽  
Corticosteroid Therapy ◽  
Antenatal Corticosteroid ◽  
Time Effects ◽  
Short Time

Antenatal corticosteroid therapy and blood pressure at 14 years of age in preterm children

2000 ◽  
Vol 98 (2) ◽  
pp. 137-142 ◽  
Author(s):  
L. W. DOYLE ◽  
G. W. FORD ◽  
N. M. DAVIS ◽  
C. CALLANAN
Keyword(s):  
Blood Pressure ◽  
Corticosteroid Therapy ◽  
Animal Species ◽  
Antenatal Corticosteroid ◽  
Antenatal Corticosteroids ◽  
Preterm Children ◽  
Clinical Hypertension ◽  
Blood Pressures ◽  
The Relationship ◽  
Mercury Sphygmomanometer

Antenatal corticosteroid therapy substantially improves the survival rate of preterm infants, with few side effects. Higher blood pressure in adulthood has been described in several animal species after exposure to antenatal corticosteroids, but there are no similar reports in humans. The objective of the present study was to determine the relationship between exposure to antenatal corticosteroid therapy and blood pressure at 14 years of age. This was a cohort study of 210 preterm survivors with birthweights of < 1501 g born in the Royal Women's Hospital, Melbourne, between 1 January 1977 and 31 March 1982. Blood pressure was measured in 177 subjects (84.3%) at 14 years of age with a standard mercury sphygmomanometer. Children exposed to antenatal corticosteroids (n = 89) had higher systolic and diastolic blood pressures than those not exposed to corticosteroids (n = 88) [mean difference (95% confidence interval) (mmHg): systolic, 4.1 (0.1–8.0); diastolic, 2.8 (0.05–5.6)]. However, few had blood pressure in the hypertensive range. It is concluded that antenatal corticosteroid therapy is associated with higher systolic and diastolic blood pressures in adolescence, and might lead to clinical hypertension in survivors well beyond birth.

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