scholarly journals The Effect of Low Dose Doxycycline Combined with Nonsurgical Periodontal Therapy on The Level of Nitric Oxide in Gingival Crevicular Fluid of Patients with Stage I Periodontitis. A randomized clinical trial.

2020 ◽  
Vol 66 (4) ◽  
pp. 2217-2228
Author(s):  
Osama Gouda ◽  
Marwa Tawfiq
Keyword(s):  
Nitric Oxide ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Low Dose ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Stage I ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

scholarly journals Non-Surgical Periodontal Therapy with Adjunctive Amoxicillin/Metronidazole or Metronidazole When No Aggregatibacter actinomycetemcomitans Is Detected—A Randomized Clinical Trial

Antibiotics ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 686
Author(s):  
Holger F. R. Jentsch ◽  
Martin Dietrich ◽  
Sigrun Eick
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Gingival Crevicular Fluid ◽  
Aggregatibacter Actinomycetemcomitans ◽  
Periodontal Therapy ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Crevicular Fluid ◽  
Systemic Antibiotics ◽  
Attachment Level

Background: The aim was to compare two different systemic antibiotics regimens adjunctive to non-surgical periodontal therapy when Aggregatibacter actinomycetemcomitans was not detected in the subgingival biofilm. Methods: A total of 58 patients with periodontitis and with no A. actinomycetemcomitans in the subgingival biofilm were treated with full-mouth subgingival instrumentation and either metronidazole (MET; n = 29) or amoxicillin/metronidazole (AMX/MET; n = 29). Probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were recorded at baseline, as well as after three and six months. Subgingival biofilm and gingival crevicular fluid were collected and analyzed for major periodontopathogens and biomarkers. Results: PD, CAL and BOP improved at 3 and 6 months (each p < 0.001 vs. baseline) with no difference between the groups. Sites with initial PD ≥ 6 mm also improved in both groups after 3 and 6 months (p < 0.001) with a higher reduction of PD in the AMX/MET group (p < 0.05). T. forsythia was lower in the AMX/MET group after 3 months (p < 0.05). MMP-8 and IL-1β were without significant changes and differences between the groups. Conclusion: When A. actinomycetemcomitans was not detected in the subgingival biofilm, the adjunctive systemic use of amoxicillin/metronidazole results in better clinical and microbiological outcomes of non-surgical periodontal therapy when the application of systemic antibiotics is scheduled.

scholarly journals The Effect of Nonsurgical Periodontal Therapy on HNP1-3 Level in Gingival Crevicular Fluid of Chronic Periodontitis Patients

2017 ◽  
Vol 65 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Ewa Dolińska ◽  
Anna Skurska ◽  
Małgorzata Pietruska ◽  
Violetta Dymicka-Piekarska ◽  
Robert Milewski ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

The effect of photobiomodulation on total amount of substance P in gingival crevicular fluid: placebo-controlled randomized clinical trial

2018 ◽  
Vol 34 (3) ◽  
pp. 517-523 ◽  
Author(s):  
Ezgi Doğanay Yıldız ◽  
Hakan Arslan ◽  
Serhat Köseoğlu ◽  
Taner Arabacı ◽  
Dursun Anıl Yıldız ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Substance P ◽  
Randomized Clinical Trial ◽  
Gingival Crevicular Fluid ◽  
Amount Of Substance ◽  
Crevicular Fluid

scholarly journals Effect of non surgical periodontal therapy combined with doxycycline on the levels of gingival crevicular fluid of nitric oxide

2019 ◽  
Vol 65 (4) ◽  
pp. 3595-3600
Author(s):  
Moshira Mohamed ◽  
Mohamed Ibrahim ◽  
Osama Sayed ◽  
Ahmed Khalil
Keyword(s):  
Nitric Oxide ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Crevicular Fluid

scholarly journals Effect of Periodontal Therapy on Crevicular Fluid Interleukin-6 and Interleukin-8 Levels in Chronic Periodontitis

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Paschalina Goutoudi ◽  
Evdoxia Diza ◽  
Malamatenia Arvanitidou
Keyword(s):  
Interleukin 6 ◽  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Strong Relationship ◽  
Periodontal Therapy ◽  
Interleukin 8 ◽  
Treatment Modalities ◽  
Enzyme Linked Immunosorbent Assay ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

Purpose. The aim of this study was to analyse the levels of interleukin-6 (IL-6) and interleukin-8 (IL-8) in gingival crevicular fluid (GCF) of patients with chronic periodontitis prior to and following surgical and/or nonsurgical periodontal therapy for a period of 32 weeks.Methods. GCF samples were obtained from 24 nondiseased and 72 diseased sites of 12 periodontal patients prior to as well as at 6, 16, and 32 weeks following non-surgical and surgical periodontal therapy. IL-6 and IL-8 levels were determined by enzyme-linked immunosorbent assay (ELISA).Results. Periodontal treatment improved all clinical parameters. Both treatment modalities resulted in similar IL-6 as well as IL-8 levels. Mean IL-6 and IL-8 concentrations were significantly higher in non-diseased compared to diseased sites and increased significantly following treatment in diseased sites. Mean total amounts of IL-6 and IL-8 (TAIL-6, TAIL-8) did not differ significantly between diseased and nondiseased sites, while following therapy TAIL-8 levels decreased significantly.Conclusions. The data suggest that periodontal therapy reduced the levels of IL-8 in GCF. However, a strong relationship between IL-6, IL-8 amounts in GCF and periodontal destruction and inflammation was not found.

Nonsurgical periodontal therapy with/without diode laser modulates metabolic control of type 2 diabetics with periodontitis: a randomized clinical trial

2016 ◽  
Vol 31 (2) ◽  
pp. 343-353 ◽  
Author(s):  
Emrah Koçak ◽  
Mehmet Sağlam ◽  
Seyit Ali Kayış ◽  
Niyazi Dündar ◽  
Levent Kebapçılar ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Metabolic Control ◽  
Diode Laser ◽  
Periodontal Therapy ◽  
Type 2 Diabetics ◽  
Nonsurgical Periodontal Therapy
Sign in / Sign up

Export Citation Format

Share Document