Fluoride Release and Recharging Ability of Glass Ionomer Cement Incorporating Hydroxyapatite Nanoparticles

The aim of this study was to assess the performance of glass ionomer cement (GIC) added with TiO2nanotubes. TiO2nanotubes [3%, 5%, and 7% (w/w)] were incorporated into GIC’s (Ketac Molar EasyMix™) powder component, whereas unblended powder was used as control. Physical-chemical-biological analysis included energy dispersive spectroscopy (EDS), surface roughness (SR), Knoop hardness (SH), fluoride-releasing analysis, cytotoxicity, cell morphology, and extracellular matrix (ECM) composition. Parametric or nonparametric ANOVA were used for statistical comparisons (α≤0.05). Data analysis revealed that EDS only detected Ti at the 5% and 7% groups and that GIC’s physical-chemical properties were significantly improved by the addition of 5% TiO2as compared to 3% and GIC alone. Furthermore, regardless of TiO2concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2at 5%. In conclusion, in the current study, nanotechnology incorporated in GIC affected ECM composition and was important for the superior microhardness and fluoride release, suggesting its potential for higher stress-bearing site restorations.

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Comparative evaluation of fluoride release from hydroxyapatite incorporated and conventional glass ionomer cement: An in vitro study

Journal of Indian Society of Pedodontics and Preventive Dentistry ◽

10.4103/0970-4388.108921 ◽

2012 ◽

Vol 30 (4) ◽

pp. 284 ◽

Cited By ~ 6

Author(s):

S Tiwari ◽

B Nandlal

Keyword(s):

Comparative Evaluation ◽

Glass Ionomer Cement ◽

In Vitro Study ◽

Vitro Study ◽

Fluoride Release ◽

Glass Ionomer ◽

Ionomer Cement

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"Effect of nano-filled surface coating agent on fluoride release from conventional glass ionomer cement: An in vitro trial"

Journal of Indian Society of Pedodontics and Preventive Dentistry ◽

10.4103/0970-4388.115703 ◽

2013 ◽

Vol 31 (2) ◽

pp. 91 ◽

Cited By ~ 8

Author(s):

S Tiwari ◽

B Nandlal

Keyword(s):

Surface Coating ◽

Glass Ionomer Cement ◽

Fluoride Release ◽

Glass Ionomer ◽

Coating Agent ◽

Ionomer Cement

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Antibacterial Activity and Fluoride Release of Glass-Ionomer Cement, Compomer and Zirconia Reinforced Glass-Ionomer Cement

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2016/16282.7676 ◽

2016 ◽

Cited By ~ 3

Author(s):

Sonia Tiwari

Keyword(s):

Antibacterial Activity ◽

Glass Ionomer Cement ◽

Fluoride Release ◽

Glass Ionomer ◽

Ionomer Cement

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Fluoride Release from a Resin-modified Glass-ionomer Cement in a Continuous-flow System: Effect of pH

Journal of Dental Research ◽

10.1177/154405910308201013 ◽

2003 ◽

Vol 82 (10) ◽

pp. 829-832 ◽

Cited By ~ 21

Author(s):

C.M. Carey ◽

M. Spencer ◽

R.J. Gove ◽

F.C. Eichmiller

Keyword(s):

Continuous Flow ◽

Glass Ionomer Cement ◽

Measuring System ◽

Fluoride Release ◽

Glass Ionomer ◽

System Effect ◽

Dental Tissues ◽

Resin Modified Glass Ionomer ◽

Dental Restorative ◽

Ionomer Cement

Fluoride is added to many dental restorative materials, including glass-ionomer cements, for the specific purpose of leaching fluoride into the surrounding tissues to provide secondary caries inhibition. During the caries process, an acidic environment attacks the dental tissues as well as the glass-ionomer cement. We hypothesized that pH significantly affects the rate of release of fluoride from the glass-ionomer cement. A continuous-flow fluoride-measuring system that monitors the amount of fluoride released over time was used to determine the release of fluoride from a resin-modified glass-ionomer cement (KetacFil®). The results show that the release rate began with a fast burst of fluoride which quickly diminished to low levels in 3 days. Under neutral pH conditions, the rate of fluoride release at 72 hrs was significantly slower than at pH 4.

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