Design and Synthesis of Peptide Derivatives Act as DNA Binding Agent and Discovery of Potent Carbonic Anhydrase Inhibitors Using Docking Studies

doi:10.21608/ejchem.2010.1221

Design and Synthesis of Peptide Derivatives Act as DNA Binding Agent and Discovery of Potent Carbonic Anhydrase Inhibitors Using Docking Studies

Egyptian Journal of Chemistry ◽

10.21608/ejchem.2010.1221 ◽

2010 ◽

Vol 53 (2) ◽

pp. 279-299

Keyword(s):

Dna Binding ◽

Carbonic Anhydrase ◽

Docking Studies ◽

Binding Agent ◽

Carbonic Anhydrase Inhibitors ◽

Design And Synthesis ◽

Peptide Derivatives

Download Full-text

Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.07.066 ◽

2015 ◽

Vol 23 (17) ◽

pp. 5311-5318 ◽

Cited By ~ 31

Author(s):

Adriano Mollica ◽

Roberto Costante ◽

Atilla Akdemir ◽

Simone Carradori ◽

Azzurra Stefanucci ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Docking Studies ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors

Download Full-text

Carbonic Anhydrase Inhibitors, Interaction of Boron Derivatives with Isozymes I and II: A New Binding Site for Hydrophobic Inhibitors at the Entrance of the Active Site as shown by Docking Studies

Journal of Enzyme Inhibition ◽

10.1080/14756360109162362 ◽

2001 ◽

Vol 16 (2) ◽

pp. 125-133 ◽

Cited By ~ 10

Author(s):

Celine Chazalette ◽

Monique Riviere-Baudet ◽

Andrea Scozzafava ◽

Francesco Abbate ◽

Zahra Ben Maarouf ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Binding Site ◽

Active Site ◽

Docking Studies ◽

Carbonic Anhydrase Inhibitors

Download Full-text

Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103897 ◽

2020 ◽

Vol 100 ◽

pp. 103897 ◽

Cited By ~ 17

Author(s):

Nebih Lolak ◽

Süleyman Akocak ◽

Cüneyt Türkeş ◽

Parham Taslimi ◽

Mesut Işık ◽

...

Keyword(s):

Molecular Docking ◽

Carbonic Anhydrase ◽

Docking Studies ◽

Carbonic Anhydrase Inhibitors ◽

Structural Motifs ◽

Molecular Docking Studies

Download Full-text

Discovery of a novel DNA binding agent via design and synthesis of new thiazole hybrids and fused 1,2,4-triazines as potential antitumor agents: Computational, spectrometric and in silico studies

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103089 ◽

2019 ◽

Vol 90 ◽

pp. 103089 ◽

Cited By ~ 4

Author(s):

Marwa H. El-Wakil ◽

Amira F. El-Yazbi ◽

Hayam M.A. Ashour ◽

Mounir A. Khalil ◽

Khadiga A. Ismail ◽

...

Keyword(s):

Dna Binding ◽

In Silico ◽

Antitumor Agents ◽

Binding Agent ◽

Design And Synthesis ◽

In Silico Studies ◽

Potential Antitumor

Download Full-text

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2019.1666836 ◽

2019 ◽

Vol 34 (1) ◽

pp. 1697-1710 ◽

Cited By ~ 2

Author(s):

Ciro Milite ◽

Giorgio Amendola ◽

Alessio Nocentini ◽

Silvia Bua ◽

Alessandra Cipriano ◽

...

Keyword(s):

Molecular Docking ◽

Carbonic Anhydrase ◽

Docking Studies ◽

Biological Evaluation ◽

Carbonic Anhydrase Inhibitors ◽

Molecular Docking Studies

Download Full-text

Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine–Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.114004 ◽

2021 ◽

pp. 114004

Author(s):

Heba T. Abdel-Mohsen ◽

Ahmed M. El Kerdawy ◽

Mohamed A. Omar ◽

Andrea Petreni ◽

Rasha M. Allam ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Design And Synthesis

Download Full-text

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.6b01607 ◽

2017 ◽

Vol 60 (3) ◽

pp. 1159-1170 ◽

Cited By ~ 54

Author(s):

Silvia Bua ◽

Lorenzo Di Cesare Mannelli ◽

Daniela Vullo ◽

Carla Ghelardini ◽

Gianluca Bartolucci ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Carbonic Anhydrase ◽

Carbonic Anhydrase Inhibitors ◽

Design And Synthesis ◽

Inflammatory Drugs ◽

Anti Inflammatory

Download Full-text

Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.10.068 ◽

2019 ◽

Vol 162 ◽

pp. 147-160 ◽

Cited By ~ 36

Author(s):

Wagdy M. Eldehna ◽

Mahmoud F. Abo-Ashour ◽

Alessio Nocentini ◽

Radwan S. El-Haggar ◽

Silvia Bua ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Active Site ◽

Antitumor Agents ◽

Hydrophobic Interactions ◽

Carbonic Anhydrase Ix ◽

Carbonic Anhydrase Inhibitors ◽

Design And Synthesis

Download Full-text

Carbohydrazones as new class of carbonic anhydrase inhibitors: Synthesis, kinetics, and ligand docking studies

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.03.014 ◽

2017 ◽

Vol 72 ◽

pp. 89-101 ◽

Cited By ~ 9

Author(s):

Sarosh Iqbal ◽

Muhammad Saleem ◽

M. Kamran Azim ◽

Muhammad Taha ◽

Uzma Salar ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Docking Studies ◽

Ligand Docking ◽

Carbonic Anhydrase Inhibitors ◽

New Class

Download Full-text

Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.01.017 ◽

2017 ◽

Vol 127 ◽

pp. 521-530 ◽

Cited By ~ 31

Author(s):

Wagdy M. Eldehna ◽

Ghada H. Al-Ansary ◽

Silvia Bua ◽

Alessio Nocentini ◽

Paola Gratteri ◽

...

Keyword(s):

Molecular Docking ◽

Carbonic Anhydrase ◽

Docking Studies ◽

Biological Evaluation ◽

Carbonic Anhydrases ◽

Carbonic Anhydrase Inhibitors ◽

Molecular Docking Studies

Download Full-text