Changes in central Macular Thickness after Uncomplicated Phacoemulsification in Diabetic versus Non-Diabetic Patients using optical Coherence Tomography (OCT)

2018 ◽  
Vol 22 (2) ◽  
pp. 249-255
Author(s):  
Ahmad Abd Allah ◽  
Mohammad Mousa ◽  
Marwa Abd Ellah ◽  
Mohammed Hamed
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Thickness ◽  
Diabetic Patients ◽  
Central Macular Thickness ◽  
Optical Coherence

scholarly journals Inter-relationship between retinal and choroidal vasculatures using optical coherence tomography angiography in normal eyes

2018 ◽  
Vol 30 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Jaeryung Oh ◽  
Daniel Jinhag Baik ◽  
Jaemoon Ahn
Keyword(s):  
Optical Coherence Tomography ◽  
Layer Thickness ◽  
Optical Coherence Tomography Angiography ◽  
Macular Thickness ◽  
Vascular Density ◽  
Inner Plexiform Layer ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
Outer Retina ◽  
Capillary Plexus

Purpose: To quantify vascular and structural macular variables in healthy eyes and to investigate correlations between these variables and age using optical coherence tomography angiography. Materials and methods: A total of 261 eyes of 261 subjects with normal fundus were included. Central macular thickness, ganglion cell layer to inner plexiform layer thickness, outer retina layer thickness, subfoveal choroidal thickness, and choroidal vascularity index were measured using optical coherence tomography. Foveal avascular zone area, vascular density, and flow void area were measured using optical coherence tomography angiography. Results: Vascular density in the superficial capillary plexus was correlated with central macular thickness, ganglion cell layer to inner plexiform layer thickness, and outer retina layer thickness ( P < 0.001, P = 0.004, and P < 0.001, respectively). Vascular density in the deep capillary plexus was correlated with central macular thickness and outer retina layer thickness ( P = 0.003 and P = 0.001, respectively). Vascular density of choriocapillaris was correlated with vascular density of superficial capillary plexus and deep capillary plexus ( P < 0.001 and P = 0.001, respectively). Conclusion: Vascular density of choriocapillaris varies with retinal vascular density rather than the structure of choroid using optical coherence tomography angiography. In contrast, retinal vascular density changes as the retinal structure. Our results provide more information about the relationship between retina and choroid.

scholarly journals Central Macular Thickness in a Healthy Mexican Population Using Huvitz Optical Coherence Tomography

2020 ◽  
Vol Volume 14 ◽  
pp. 3931-3940
Author(s):  
Renata García-Franco ◽  
Dalia Méndez-Marín ◽  
Marlon García-Roa ◽  
Paulina Ramirez-Neria ◽  
Diego Valera-Cornejo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Thickness ◽  
Mexican Population ◽  
Central Macular Thickness ◽  
Optical Coherence

Hemodialysis-Induced Alterations in Macular Thickness Measured by Optical Coherence Tomography in Diabetic Patients with End-Stage Renal Disease

2012 ◽  
Vol 227 (2) ◽  
pp. 90-94 ◽  
Author(s):  
Panagiotis G. Theodossiadis ◽  
Sofia Theodoropoulou ◽  
Georgia Neamonitou ◽  
Vlassis Grigoropoulos ◽  
Vasilios Liarakos ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Macular Thickness ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An Optical Coherence Tomography Study

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gordon S. K. Yau ◽  
Jacky W. Y. Lee ◽  
Tiffany T. Y. Woo ◽  
Raymond L. M. Wong ◽  
Ian Y. H. Wong
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
Retinal Nerve Fibre Layer ◽  
Macular Thickness ◽  
Chinese Children ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
The Mean ◽  
Nerve Fibre Layer ◽  
Chinese Subjects

Purpose.To investigate the central macular thickness (CMT) in myopic, emmetropic, and hyperopic Chinese children using Optical Coherence Tomography.Methods.168 right eyes of Chinese subjects aged 4–18 were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<−1.0 D); emmetropes (≥−1.0 to ≤+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after age adjustment. The CMT was correlated with age, axial length, and peripapillary retinal nerve fibre layer (RNFL).Results.The mean CMT was274.9±50.3 μm and the mean population age was7.6±3.3years. The CMT was thickest in the myopes (283.3±57.3 μm,n=56), followed by the hyperopes (266.2±55.31 μm,n=60) and then emmetropes (259.8±28.7 μm,n=52) (allP<0.0001). When adjusted for age, myopes had a thicker CMT than the other 2 groups (allP<0.0001) but there was no CMT difference between the emmetropes and hyperopes (P>0.05). There was no significant correlation between CMT with age, axial length, or peripapillary RNFL (allP≥0.2).Conclusion.Chinese children with myopia had a thicker CMT than those with emmetropia or hyperopia. There was no correlation of the CMT with age, axial length, or peripapillary RNFL thickness.

scholarly journals A Comparative Evaluation of Macular Thickness after Phacoemulsification and Manual SICS in Diabetic Patients by Optical Coherence Tomography

2021 ◽  
Vol 8 (7) ◽  
pp. 468-472
Author(s):  
Saswati Biswas ◽  
Santosh Yadawrao Ingle ◽  
Samiran Das
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Macular Edema ◽  
Macular Thickness ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Small Incision Cataract Surgery ◽  
High Rise ◽  
Small Incision ◽  
Before And After

Background: The main aim of the study is to compare the change in macular thickness after uncomplicated phacoemulsification versus uncomplicated manual SICS in known diabetic patients by optical coherence tomography Methods: This study was an observational study involving 50 patients with each group having 25 patients. Group 1 was operated with Phacoemulsification through limbal 2.8 mm incision with Foldable PCIOL implantation. & Manual small incision cataract surgery through 5.5 to 6.5 mm incision with sclerocorneal tunnel with PMMA PCIOL implantation. For all patients, macular OCT was performed during preoperative period & post-op 1st day,7th day, 1st month, 3rd month & 6th month. Statistical software SPSS, version 21.0 was used for statistical analysis. Results: In both PHACO & SICS group MCFT rose steadily during post-operative period and SICS group shows high rise during follow up.The MCFT shows a difference between PHACO & SICS group with the highest MCFT observed in 1st month follow up i.e., 231.6 micrometer (SD ±7.831) in PHACO group & 241.64 (SD ±7.35) micrometer in SICS group. The MCFT returned to near pre-op value by the 6th month. Conclusion: There is no effect of age and sex on macular thickness before and after in both PHACO and SICS groups. In SICS group significant macular thickness was observed as compared to PHACO group, so there should be more cautious to undertake SICS in those patients who are at risk of developing macular edema or who have a higher macular thickness as seen in diabetes patients. Keywords: Phacoemulsification (PHACO), small incision cataract surgery (SICS), Cystoid macular edema.

scholarly journals Quantitative analysis of optical coherence tomography angiography metrics in diabetic retinopathy

2020 ◽  
Vol 12 ◽  
pp. 251584141989745 ◽  
Author(s):  
Hamid Safi ◽  
Pasha Anvari ◽  
Dariush Naseri ◽  
Hamideh Shenazandi ◽  
Pegah Kazemi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Optical Coherence Tomography Angiography ◽  
Macular Thickness ◽  
Foveal Avascular Zone ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
Ellipsoid Zone ◽  
Avascular Zone

Purpose: To evaluate the correlation of the visual acuity and diabetic retinopathy stage using optical coherence tomography and optical coherence tomography angiography metrics. Methods: In this prospective study, optical coherence tomography and optical coherence tomography angiography images of patients with different stages of diabetic retinopathy were obtained. In optical coherence tomography angiography images, the size of foveal avascular zone, central macular thickness, and vessel density at superficial and deep capillary layers of the macula were measured. In optical coherence tomography images, the presence of intraretinal cyst, disorganization of retinal inner layer, and ellipsoid zone and external limiting membrane disruption were evaluated. The associations between the variables with visual acuity and diabetic retinopathy stage were analyzed. Results: In total, 68 eyes of 38 patients with a mean age of 58.96 ± 10.59 years were included. In total, 34 eyes were categorized as non-proliferative diabetic retinopathy, 14 as active, and 20 as regressed proliferative diabetic retinopathy. Univariate analysis showed deep parafoveal vessel density, central macular thickness, ellipsoid zone disruption, disorganization of retinal inner layer, and external limiting membrane disruption had a significant relationship with visual acuity. However, in multivariate analysis, only central macular thickness and ellipsoid zone disruption had significant association with visual acuity ( p = 0.02 and p = 0.01, respectively). There was a significant difference in deep parafoveal vessel density ( p = 0.04), but not in foveal avascular zone area, between different stages of diabetic retinopathy. Conclusion: In this study, the foveal avascular zone area did not correlate with visual acuity and different stages of diabetic retinopathy. Structural abnormalities on optical coherence tomography images with especial focus on outer retinal disruption provided more reliable predictors for visual acuity outcomes in patients with diabetic retinopathy.

A Study of Retinal Nerve Fiber Layer Thickness by using Spectral Domain Optical Coherence Tomography in Older Adults with Diabetes Mellitus

2019 ◽  
Vol 15 (1) ◽  
pp. 17-21
Author(s):  
Devendra Sharma ◽  
Arvind Chauhan ◽  
Avisha Mathur
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Rnfl Thickness

Introduction: Peripapillary retinal nerve fiber layer (RNFL) thinning occurs in the diabetic patients earlier than the detectable diabetic retinopathy. We conducted this study to evaluate the RNFL thickness and macular thickness in elderly diabetic patients using optical coherence tomography in comparison to healthy controls. Material and methods: One fifty study participants were divided in 3 groups (50 each): normal subjects, patients with diabetes with no detectable diabetic retinopathy (NDR) and patients with diabetic retinopathy (DR) of differing severity. The RNFL thickness and macular thickness was measured using spectral-domain optical coherence tomography (SD OCT). Results: The RNFL thickness around the optic disc differed significantly among all the 3 groups and tended to become thinner as the patient develops DR in elderly subjects. The mean, superior-temporal and upper nasal peripapillary RNFL thickness differed among all the 3 groups. We observed that, mean superior, temporal, inferior and nasal RNFL tended to be thinner as the patient develops DR. Conclusion: The RNFL thickness, macular thickness and ganglion cell complex thinning differed significantly between the healthy group and diabetic group without clinical DR. The RNFL thinning (measured by Spectral-domain OCT) is an early neurodegenerative ocular change in diabetic patients even before onset of diabetic retinopathy.

Evaluation of optical coherence tomography findings in adolescents with genetic generalized epilepsy

2021 ◽  
pp. 112067212110497
Author(s):  
Aysin Tuba Kaplan ◽  
Sibel Oskan Yalcın ◽  
Safiye Gunes Sager
Keyword(s):  
Optical Coherence Tomography ◽  
Regression Analysis ◽  
Macular Thickness ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
Monotherapy Group ◽  
Newly Diagnosed ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Generalized Epilepsy

Objective To evaluate retinal nerve fiber layer (RNFL) thickness, central macular thickness (CMT), and subfoveal choroid thickness (CT) by using optical coherence tomography (OCT) in adolescents with newly diagnosed epilepsy and patients who had been using Na valproate (VPA) for at least 1 year. Methods We examined 60 patients with genetic generalized epilepsy (GGE) aged 8–17 years. Thirty patients with newly diagnosed GGE who were evaluated before the beginning of the therapy and another 30 patients who were chosen from among adolescents with epilepsy using VPA for at least 1 year were included in the study. Results Nasal quadrant RNFL thickness and CMT measurements were significantly lower in the monotherapy group compared with the newly diagnosed group ( p = 0.044 and p = 0.032, respectively). CT measurements were not significantly different between the groups ( p = 0.413). There was a negative correlation in regression analysis between the duration of drug use and RNFL thickness in all quadrants. Conclusion According to our study, we observed thinning of the nasal RNFL and macular thickness in adolescents with epilepsy who were using Na valproate for at least 1 year and that as the duration of use increased, the thinning occurred in all RNFL quadrants. Further studies with larger series are needed to better understand the effects of both epilepsy and VPA on the eye.

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