Dietary antioxidants and antioxidant supplements do not appear to be effective for the primary prevention of age-related macular degeneration

2007 ◽  
Vol &NA; (1610) ◽  
pp. 16
Author(s):  
&NA;
BMJ ◽  
2007 ◽  
Vol 335 (7623) ◽  
pp. 755 ◽  
Author(s):  
Elaine W-T Chong ◽  
Tien Y Wong ◽  
Andreas J Kreis ◽  
Julie A Simpson ◽  
Robyn H Guymer

Ophthalmology ◽  
2008 ◽  
Vol 115 (2) ◽  
pp. 334-341 ◽  
Author(s):  
Jennifer S.L. Tan ◽  
Jie Jin Wang ◽  
Victoria Flood ◽  
Elena Rochtchina ◽  
Wayne Smith ◽  
...  

2005 ◽  
Vol 140 (6) ◽  
pp. 1020-1026 ◽  
Author(s):  
Siobhan E. Moriarty-Craige ◽  
Joanne Adkison ◽  
Michael Lynn ◽  
Gary Gensler ◽  
Susan Bressler ◽  
...  

2021 ◽  
Vol 13 ◽  
pp. 251584142110304
Author(s):  
Mousumi Banerjee ◽  
Rohan Chawla ◽  
Atul Kumar

Age-related macular degeneration (ARMD) is one of the prominent causes of central visual loss in the older age group in the urbanized, industrialized world. In recent years, many epidemiological studies and clinical trials have evaluated the role of antioxidants and micronutrients to prevent the progression of ARMD. In this article, we review some of these major studies. In addition, we review the absorption and bioavailability and possible undesirable effects of these nutrients after ingestion. The role of genotypes and inappropriate use of these supplements are also discussed. From all the above evidence, we conclude that it may not be prudent to prescribe these formulations without a proper assessment of the individual’s health and dietary status. The effectiveness of all the components in antioxidant formulations is controversial. Thus, these supplements should not be prescribed just for the purpose of providing patients some kind of therapy, which may give a false sense of mental satisfaction.


2021 ◽  
Vol 62 (11) ◽  
pp. 1502-1508
Author(s):  
Jeong Ho Na ◽  
Jae Wan Lim ◽  
Jong Wook Bang ◽  
Kang Yeun Pak ◽  
Hyun Woong Kim

Purpose: To investigate the use of second AREDS2 formula in patients with intermediate or advanced age-related macular degeneration.Methods: A prospective survey was conducted between December 2019 and July 2020. The questionnaire consisted of 24 questions on demographics, disease perception, and formula intake.Results: The survey included 100 patients (males, 56%; age [>60 years], 89%). We found that 66%, 84%, and 93% of patients had a good understanding of their disease, had stopped smoking, and were aware of the need for antioxidant supplements; 58% of patients were aware of the supplement they were prescribed, and 63.8% (37% of total) were using the AREDS2 formula. Only 8% of patients had knowledge regarding the supplement ingredients, and 91% consumed the supplement daily. Patients with long disease duration used supplements less frequently (p < 0.05). Older patients and those with a low education level had a limited perception of the disease (p < 0.05).Conclusions: In this prospective survey, some patients consumed supplements other than the AREDS2 formula. Further studies are required to determine ways to increase the use of the AREDS2 formula.


Ophthalmology ◽  
2014 ◽  
Vol 121 (3) ◽  
pp. 667-675 ◽  
Author(s):  
Jie Jin Wang ◽  
Gabriëlle H.S. Buitendijk ◽  
Elena Rochtchina ◽  
Kristine E. Lee ◽  
Barbara E.K. Klein ◽  
...  

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