Structure-Activity Relationships for the Design of Small-Molecule Inhibitors

Small Molecule Inhibitors of KDR (VEGFR-2) Kinase: An Overview of Structure Activity Relationships

Current Topics in Medicinal Chemistry ◽

10.2174/1568026023393273 ◽

2002 ◽

Vol 2 (9) ◽

pp. 973-1000 ◽

Cited By ~ 63

Author(s):

Stephen Boyer

Keyword(s):

Small Molecule ◽

Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.09.019 ◽

2014 ◽

Vol 22 (22) ◽

pp. 6490-6502 ◽

Cited By ~ 4

Author(s):

Alex W. Ireland ◽

Theodore A. Gobillot ◽

Tushar Gupta ◽

Sandlin P. Seguin ◽

Mary Liang ◽

...

Keyword(s):

Small Molecule ◽

Simian Virus 40 ◽

Simian Virus ◽

T Antigen ◽

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103264 ◽

2019 ◽

Vol 92 ◽

pp. 103264 ◽

Cited By ~ 2

Author(s):

Yoana D. Petrova ◽

Katty Wadda ◽

Amit Nathubhai ◽

Maksims Yevglevskis ◽

Paul J. Mitchell ◽

...

Keyword(s):

Small Molecule ◽

Structure–activity relationships of small molecule inhibitors of RAGE-Aβ binding

Tetrahedron ◽

10.1016/j.tet.2013.05.079 ◽

2013 ◽

Vol 69 (36) ◽

pp. 7653-7658 ◽

Cited By ~ 3

Author(s):

Nathan T. Ross ◽

Rashid Deane ◽

Sheldon Perry ◽

Benjamin L. Miller

Keyword(s):

Small Molecule ◽

Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure–activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2016.02.014 ◽

2016 ◽

Vol 114 ◽

pp. 345-364 ◽

Cited By ~ 4

Author(s):

Shigeo Hayashi ◽

Katsuyo Ohashi ◽

Sachiko Mihara ◽

Eriko Nakata ◽

Chie Emoto ◽

...

Keyword(s):

Small Molecule ◽

Orphanin Fq ◽

Design Synthesis ◽

WITHDRAWN: Structure-activity relationship study of small molecule inhibitors of the DEPTOR-mTOR interaction

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2017.08.050 ◽

2017 ◽

Author(s):

Jihye Lee ◽

Yijiang Shi ◽

Mario Vega ◽

Yonghui Yang ◽

Joseph Gera ◽

...

Keyword(s):

Small Molecule ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

Synthesis and structure–activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.01.104 ◽

2007 ◽

Vol 17 (8) ◽

pp. 2171-2178 ◽

Cited By ~ 8

Author(s):

Martin W. Rowbottom ◽

Troy D. Vickers ◽

Junko Tamiya ◽

Mingzhu Zhang ◽

Brian Dyck ◽

...

Keyword(s):

Small Molecule ◽

Hormone Receptor ◽

Structure Activity ◽

Melanin Concentrating Hormone

Synthesis and structure–activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.06.049 ◽

2006 ◽

Vol 16 (18) ◽

pp. 4922-4930 ◽

Cited By ~ 10

Author(s):

Sarah Hudson ◽

Mehrak Kiankarimi ◽

Martin W. Rowbottom ◽

Troy D. Vickers ◽

Dongpei Wu ◽

...

Keyword(s):

Small Molecule ◽

Hormone Receptor ◽

Structure Activity ◽

Melanin Concentrating Hormone

A Comprehensive Overview of Structure‐Activity Relationships of Small‐Molecule Splicing Modulators Targeting SF3B1 as Anticancer Agents

ChemMedChem ◽

10.1002/cmdc.202000642 ◽

2020 ◽

Vol 15 (22) ◽

pp. 2098-2120

Author(s):

Datong Zhang ◽

Fancui Meng

Keyword(s):

Small Molecule ◽

Anticancer Agents ◽

Comprehensive Overview ◽

Small molecule antagonists of the gonadotropin-releasing hormone (GnRH) receptor: Structure–activity relationships of small heterocyclic groups appended to the 2-phenyl-4-piperazinyl-benzimidazole template

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.02.043 ◽

2009 ◽

Vol 19 (7) ◽

pp. 1986-1990 ◽

Cited By ~ 9

Author(s):

Diane B. Hauze ◽

Murty V. Chengalvala ◽

Joshua E. Cottom ◽

Irene B. Feingold ◽

Lloyd Garrick ◽

...

Keyword(s):

Small Molecule ◽

Gnrh Receptor ◽

Gonadotropin Releasing Hormone ◽

Releasing Hormone ◽

Receptor Structure ◽