Prediction of Drug Metabolism: The Case of Cytochrome P450 2D6

2005 ◽  
Vol 2 (1) ◽  
pp. 571-586
Author(s):  
Nico P. E.Vermeulen
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Cytochrome P450 2D6 ◽  
P450 2D6

scholarly journals Human liver mitochondrial cytochrome P450 2D6 - individual variations and implications in drug metabolism

FEBS Journal ◽  
2009 ◽  
Vol 276 (13) ◽  
pp. 3440-3453 ◽  
Author(s):  
Michelle Cook Sangar ◽  
Hindupur K. Anandatheerthavarada ◽  
Weigang Tang ◽  
Subbuswamy K. Prabu ◽  
Martha V. Martin ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Metabolism ◽  
Human Liver ◽  
Mitochondrial Cytochrome ◽  
Cytochrome P450 2D6 ◽  
Individual Variations ◽  
P450 2D6

Probing Small-Molecule Binding to Cytochrome P450 2D6 and 2C9: An In Silico Protocol for Generating Toxicity Alerts

ChemMedChem ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. 2088-2101 ◽  
Author(s):  
Gianluca Rossato ◽  
Beat Ernst ◽  
Martin Smiesko ◽  
Morena Spreafico ◽  
Angelo Vedani
Keyword(s):  
Cytochrome P450 ◽  
Small Molecule ◽  
In Silico ◽  
Cytochrome P450 2D6 ◽  
P450 2D6
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