Induction of Apoptotic Cell Death in Tumor Cells by S100A8/A9 Released from Inflammatory Cells Upon Cellular Activation

Author(s):  
C. Kerkhoff ◽  
S. Ghavami
2018 ◽  
Vol 420 ◽  
pp. 210-227 ◽  
Author(s):  
Jing Ye ◽  
Ruonan Zhang ◽  
Fan Wu ◽  
Lijuan Zhai ◽  
Kaifeng Wang ◽  
...  

2018 ◽  
Vol 94 (5) ◽  
pp. 1246-1255 ◽  
Author(s):  
Sean T. Campbell ◽  
Caroline E. Franks ◽  
Adam L. Borne ◽  
Myungsun Shin ◽  
Liuzhi Zhang ◽  
...  

1998 ◽  
Vol 4 (S2) ◽  
pp. 1036-1037
Author(s):  
M. C. Willingham

Several clinically important anti-cancer agents exert their effects on tumor cells through interference with the function of microtubules. In addition to the Vinca alkaloids, such as vinblastine and vincristine, the taxanes, such as paclitaxel (Trade Name: Taxol), kill tumor cells through a microtubular target. Treatment with taxol leads to the inability of microtubules to depolymerize, leading to the formation of large intracellular microtubular bundles. In tumor cells that progress through the cell cycle, this leads to the inability of these cells to disassembly interphase microtubule networks and a failure to form functional mitotic spindles. These cells arrest in M phase, from which they eventually progress, either by the induction of apoptotic cell death, or by micronucleation and the formation of tetraploid cells. There is also the possibility that taxol has other effects on the regulation of genes or other systems to enhance cell killing, perhaps through lowering the threshold of cells to the induction of apoptotic cell death.


2006 ◽  
Vol 340 (2) ◽  
pp. 560-566 ◽  
Author(s):  
Yusuke Fujiwara ◽  
Kei Kawada ◽  
Daiki Takano ◽  
Susumu Tanimura ◽  
Kei-ichi Ozaki ◽  
...  

1996 ◽  
Vol 51 (7) ◽  
pp. 931-940 ◽  
Author(s):  
Frank A. Fornari ◽  
W.David Jarvis ◽  
Steven Grant ◽  
Michael S. Orr ◽  
Joyce K. Randolph ◽  
...  

2008 ◽  
Vol 27 (5) ◽  
pp. 432-439 ◽  
Author(s):  
Željko Žižak ◽  
Zorica Juranić ◽  
Dejan Opsenica ◽  
Bogdan A. Šolaja

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Sung‐Gook Cho ◽  
Stafford Joe Lewis ◽  
Dali Li ◽  
Jian Luo ◽  
Mingyao Liu

2009 ◽  
Vol 8 (8) ◽  
pp. 2276-2285 ◽  
Author(s):  
Eun-Sil Sung ◽  
Kyung-Jin Park ◽  
Seung-Hyun Lee ◽  
Yoon-Seon Jang ◽  
Sang-Koo Park ◽  
...  

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