An Efficient Synthesis of 3,4-dihydro-2(1H)-pyrimidinones from Aldehyde Bisulfite Adducts using Recyclable Wang Resin Supported Sulfonic Acid Catalyst
Keyword(s):
One Pot
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: An efficient one pot multicomponent synthesis of 3,4- dihydropyrimidin-2(1H)-ones has been developed from aldehyde bisulfite adducts, ethyl acetoacetate and urea using recyclable polymer supported sulfonic acid catalyst. This new method provides several advantages over previous synthesis including high product yields, commercially viable, minimal workup operations and sustainable chemical practices.