The Synthesis and Use of BMS 204352 (MaxiPostTM)

2020 ◽  
Vol 17 (1) ◽  
pp. 67-73
Author(s):  
Renato Dalpozzo
Keyword(s):  
Potassium Channel ◽  
The State ◽  
Synthetic Methods ◽  
Potassium Channel Opener ◽  
Research Fields ◽  
Channel Opener ◽  
In Vivo Tests ◽  
State Of Art

MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.

Effects of the New Potassium Channel Opener JTV-506 on Coronary Vessels in vitro and in vivo

2011 ◽  
Vol 49 (03) ◽  
pp. 199-206
Author(s):  
Yukiya Hirata ◽  
Atsunori Kanada ◽  
Hisato Miyai ◽  
Yukiyo Mabuchi ◽  
Kazuo Aisaka
Keyword(s):  
Potassium Channel ◽  
Coronary Vessels ◽  
Potassium Channel Opener ◽  
Channel Opener

Airway pharmacology of the potassium channel opener, HOE 234, in guinea pigs: in vitro and in vivo studies

1992 ◽  
Vol 210 (1) ◽  
pp. 69-75 ◽  
Author(s):  
Heinrich C. Englert ◽  
Klaus Wirth ◽  
Doris Gehring ◽  
Ute Fürst ◽  
Udo Albus ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Guinea Pigs ◽  
In Vivo Studies ◽  
Potassium Channel Opener ◽  
Channel Opener

EFFECTS OF THE POTASSIUM CHANNEL OPENER AND NITRIC OXIDE DONOR NICORANDIL ON THE URETER MOTILITY OF PIGS IN VITRO AND IN VIVO

1999 ◽  
pp. 86
Author(s):  
Hansjorg Danuser ◽  
Ruth Weiss ◽  
Meike Mevissen ◽  
Daniela Abel ◽  
Gunter Scholtysik ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Potassium Channel ◽  
Nitric Oxide Donor ◽  
Potassium Channel Opener ◽  
Channel Opener

scholarly journals Pharmacological property of a new potassium channel opener, TCV-295 in vitro.

1993 ◽  
Vol 61 ◽  
pp. 220
Author(s):  
Yumiko Awane ◽  
Keiji Kusumoto ◽  
Shouhei Hashiguchi ◽  
Mitsuru Shiraishi ◽  
Toshifumi Watanabe
Keyword(s):  
Potassium Channel ◽  
Pharmacological Property ◽  
Potassium Channel Opener ◽  
Channel Opener

Synthesis and potassium KV7 channel opening activity of thioether analogues of the analgesic flupirtine

2018 ◽  
Vol 16 (45) ◽  
pp. 8695-8699 ◽  
Author(s):  
Christian Bock ◽  
Kristin Beirow ◽  
Abdrrahman S. Surur ◽  
Lukas Schulig ◽  
Anja Bodtke ◽  
...  
Keyword(s):  
Potassium Channel ◽  
Oxidation Products ◽  
Potassium Channel Opener ◽  
Channel Opener ◽  
Channel Opening

Benign by design: active sulfide-analogues of potassium channel opener flupirtine do not form reactive oxidation products in vitro.

scholarly journals Bronchodilating effects of the novel potassium channel opener HOE 234 in human airways in vitro.

1993 ◽  
Vol 35 (3) ◽  
pp. 318-320 ◽  
Author(s):  
M. Miura ◽  
MG Belvisi ◽  
JK Ward ◽  
S. Tadjkarimi ◽  
MH Yacoub ◽  
...  
Keyword(s):  
Potassium Channel ◽  
The Novel ◽  
Potassium Channel Opener ◽  
Channel Opener ◽  
Human Airways
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