Cerebellar Dysfunction in an Elderly Male After a Brief Course of Metronidazole

2019 ◽  
Vol 14 (2) ◽  
pp. 163-166 ◽  
Author(s):  
Upinder Kaur ◽  
Ishan Kumar ◽  
Anup Singh ◽  
Mukesh Kumar ◽  
Sankha Shubhra Chakrabarti

Background:Metronidazole, a widely used antibacterial and antiprotozoal drug, is often the drug of choice in amoebic liver abscess. The drug, otherwise safe, can cause serious central nervous disturbances in rare circumstances. Case Report:Here, we report a case of cerebellar dysfunction in the form of slurring of speech and episodes of falls, in an elderly male following a three-week course of metronidazole therapy. Results and Conclusion:The patient manifested classic radiologic features of metronidazole neurotoxicity. Marked improvement in clinical symptoms was seen following drug discontinuation.

1977 ◽  
Vol 13 (1) ◽  
pp. 53-55
Author(s):  
B. MOORTHY ◽  
S. MEHTA ◽  
S. K. MITRA ◽  
I. C. PATHAK

2018 ◽  
Vol 17 (1) ◽  
pp. 155-157
Author(s):  
ASM Rizwan ◽  
Md Rakibul Islam ◽  
Md Ghulam Yusuf

In Bangladesh tuberculosis (TB) cases are fairly common but isolated hepatobilliary TB cases are extremely rare. Liver abscess due to TB without involvement of any other site causes diagnostic delay and can easily confuse with pyogenic or amoebic liver abscess or haepatocellular carcinoma. We present a case of a 44-years-old diabetic,normotensive male who presented with prolonged high grade fever with chill and rigor with tender hepatomegally. He was put on treatment for liver abscess but was not responding. Later on, histopathology was done and it turned out to be a case of tuberculous liver abscess.Bangladesh Journal of Medical Science Vol.17(1) 2018 p.155-157


2019 ◽  
Vol 20 ◽  
pp. 493-498 ◽  
Author(s):  
Giuseppe Marenga ◽  
Silvia Traficante ◽  
Serena Ragonici ◽  
Claudia Vincenzi ◽  
Maura Rocchetti ◽  
...  

Author(s):  
Shwetabh Pradhan ◽  
Keshri Amit ◽  
Biant Singh

Objectives: Liver abscess (LA) is defined as collection of purulent material in liver parenchyma which can be due to bacterial, parasitic, fungal, or mixed infection. The liver abscess is mainly classified into amoebic and pyogenic. This present study was to evaluate the aetiology, clinical profile, management and prognosis of liver abscess patients. Methods: A detail history, clinical examinations and relevant investigations were performed to all liver abscess patients. Investigations was performed like as routine blood investigations, chest x-ray, PA view, X-ray abdomen, AP view, ultrasound abdomen, CT scan abdomen (if needed).  Culture and sensitivity of the aspirate was performed. Results: Data was analysed by using simple statistical methods with the help of MS-Office software. Conclusions: Liver abscess was commonly seen in elderly age groups. Male was more preponderance than females. Amoebic liver abscess was commonly   found. Amoebic liver abscess was commonly seen in alcoholic patients. Abdominal pain, fever and abdominal distension were common clinical symptoms. Tenderness on right hypochondrial, intercostal region and hepatomegaly were the common clinical sign of liver abscess. Abscess was mostly seen in right lobe than left lobe. Most of the patients were managed by percutaneous single aspiration. If aspiration was failed, percutaneous catheter drainage was the choice for management of liver abscess. Hence, A very prompt recognition is important in instituting effective management and achieving good outcomes.  Because of the nonspecific symptoms and laboratory findings, the presence of predisposing factors can be helpful in increasing the level of diagnostic suspicion.  The key to successful outcome in the management of liver abscess is early diagnosis and appropriate therapy. Keywords: Liver abscess, age group, amoebic liver abscess, pyogenic liver abscess, alcoholic, management of liver abscess


Author(s):  
Nagina Shahzadi ◽  
Uzma Rubab ◽  
Nadeem Hashmat ◽  
Naureen Satti

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