scholarly journals Cataract Surgery in Patients with Keratoconus: Pearls and Pitfalls

2017 ◽  
Vol 11 (1) ◽  
pp. 194-200 ◽  
Author(s):  
F. Aiello ◽  
QJ Nasser ◽  
C. Nucci ◽  
R.I. Angunawela ◽  
Z. Gatzioufas ◽  
...  

Background: Keratoconus (KC) is a common ectatic disorder resulting in progressive corneal thinning and irregular astigmatism. It has been observed that patients affected by KC are more likely to develop lens opacities earlier compared to non-keratoconic patients. Objective: Intraocular lens (IOL) selection and refractive outcome prediction are among a number of factors that can make cataract surgery in keratoconic patients challenging. Accurate biometry is often difficult to obtain due to unreliable K measurements and lack of dedicated biometric formulae. The use of toric IOLs has also been investigated. Conclusions: Determining the stage of KC, pre-operative patient counselling and the preferred method of refractive correction are all crucial to obtain successful postoperative outcomes and good patient satisfaction. The use of toric IOLs can achieve good results only in selected low-grade keratoconic eyes.

2018 ◽  
pp. 89-93
Author(s):  
M.M. Konovalova ◽  
◽  
A.A. Gorenskiy ◽  
S.V. Ivanov ◽  
M.L. Zenina ◽  
...  
Keyword(s):  

Author(s):  
Hanefi Çakır ◽  
Mehmet Tetikoğlu ◽  
Medine Aslı Yıldırım ◽  
Feyza Altın ◽  
Uğur Çelik

2019 ◽  
Author(s):  
Piotr Kanclerz ◽  
Christoph Leisser ◽  
Andrzej Grzybowski ◽  
Paweł Lipowski

Abstract Background Cataract development is common in phakic eyes filled with silicone oil (SO), necessitating subsequent cataract removal. This study evaluated the refractive outcome in eyes filled with SO undergoing phacoemulsification cataract surgery (PCS). Methods This retrospective study evaluated patients with SO tamponade who were scheduled for PCS. Results Subjects (n=26) were followed-up for 29.5 ± 13.9 months after cataract surgery. The median spherical equivalent refraction (SER) was +5.3 D (interquartile range [IQR] +2.9 to +6.7) before PCS, and +3.4 D (IQR +2.0 to +4.4) after PCS. Within the follow-up period retinal reattachment after SO removal was achieved in 15 out of 26 eyes (57.7%). In 13 eyes assessment of refraction after SO-removal was possible, and showed a myopic shift of -4.6 D (IQR -2.9 to -7.3) in the SER. After SO removal, 5 of 13 eyes (38.5%) were within ±1.0 D of the target refraction, while 9 out of 13 eyes (69.2%) were within ±2.0 D. Conclusions The refractive outcome after PCS for eyes filled with SO is less predictable than that for normal eyes. Some of the eyes undergoing silicone oil injection may require long-term tamponade.


2020 ◽  
Vol 21 (12) ◽  
pp. 4459 ◽  
Author(s):  
Andrea Baragetti ◽  
Alberico Luigi Catapano ◽  
Paolo Magni

Chronic low-grade inflammation, through the specific activation of the NACHT leucine-rich repeat- and PYD-containing (NLRP)3 inflammasome-interleukin (IL)-1β pathway, is an important contributor to the development of atherosclerotic cardiovascular disease (ASCVD), being triggered by intracellular cholesterol accumulation within cells. Within this pathological context, this complex pathway is activated by a number of factors, such as unhealthy nutrition, altered gut and oral microbiota, and elevated cholesterol itself. Moreover, evidence from autoinflammatory diseases, like psoriasis and others, which are also associated with higher cardiovascular disease (CVD) risk, suggests that variants of NLRP3 pathway-related genes (like NLRP3 itself, caspase recruitment domain-containing protein (CARD)8, caspase-1 and IL-1β) may carry gain-of-function mutations leading, in some individuals, to a constitutive pro-inflammatory pattern. Indeed, some reports have recently associated the presence of specific single nucleotide polymorphisms (SNPs) on such genes with greater ASCVD prevalence. Based on these observations, a potential effective strategy in this context may be the identification of carriers of these NLRP3-related SNPs, to generate a genomic score, potentially useful for a better CVD risk prediction, and, possibly, for personalized therapeutic approaches targeted to the NLRP3-IL-1β pathway.


2017 ◽  
Vol 26 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Oliver L. Yeh ◽  
Karine D. Bojikian ◽  
Mark A. Slabaugh ◽  
Philip P. Chen

2017 ◽  
Vol 11 (01) ◽  
pp. 23
Author(s):  
Tiago Bravo Ferreira ◽  

Meticulous correction of astigmatism during cataract surgery is mandatory in cases of multifocal intraocular lens (IOL) implantation. Toric multifocal IOLs allow predictable astigmatic correction during cataract surgery. In this editorial, we review our investigation on the Tecnis ZMT IOL (Abbott Medical Optics, CA, US) as well as other recent developments in multifocal toric IOLs.


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