Phase II Drug Metabolism and Individualized Drug Therapy: A Focus on Functional Genetic Variation in UDP-Glucuronosyltransferases

Yoshihiro Maruo; Hiroko Takahashi; Katusyuki Matsui; Hiroshi Sato; Yoshihiro Takeuchi

doi:10.2174/187569210791383901

Phase II Drug Metabolism and Individualized Drug Therapy: A Focus on Functional Genetic Variation in UDP-Glucuronosyltransferases

Current Pharmacogenomics and Personalized Medicine ◽

10.2174/187569210791383901 ◽

2010 ◽

Vol 8 (2) ◽

pp. 146-166 ◽

Cited By ~ 3

Author(s):

Yoshihiro Maruo ◽

Hiroko Takahashi ◽

Katusyuki Matsui ◽

Hiroshi Sato ◽

Yoshihiro Takeuchi

Keyword(s):

Genetic Variation ◽

Drug Therapy ◽

Drug Metabolism ◽

Phase Ii ◽

Functional Genetic Variation ◽

Individualized Drug Therapy ◽

Phase Ii Drug Metabolism

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The effect of transcatheter arterial chemoembolization on phase II drug metabolism enzymes in patients with hepatocellular carcinoma

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-009-1040-7 ◽

2009 ◽

Vol 65 (2) ◽

pp. 347-352 ◽

Cited By ~ 3

Author(s):

Yan Zhang ◽

Yanyan Jia ◽

Xinyou Liu ◽

Linna Liu ◽

Qingwei Wang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Drug Metabolism ◽

Phase Ii ◽

Transcatheter Arterial Chemoembolization ◽

Metabolism Enzymes ◽

Arterial Chemoembolization ◽

Phase Ii Drug Metabolism

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“Phase I and Phase II” Drug Metabolism: Terminology that we Should Phase Out?

Drug Metabolism Reviews ◽

10.1080/03602530500251220 ◽

2005 ◽

Vol 37 (4) ◽

pp. 575-580 ◽

Cited By ~ 44

Author(s):

P. David Josephy ◽

F. Peter Guengerich ◽

John O. Miners

Keyword(s):

Drug Metabolism ◽

Phase I ◽

Phase Ii ◽

Phase Out ◽

Phase Ii Drug Metabolism

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Enzymatic Basis of Phase I and Phase II Drug Metabolism

Enzyme- and Transporter-Based Drug-Drug Interactions ◽

10.1007/978-1-4419-0840-7_1 ◽

2009 ◽

pp. 3-25 ◽

Cited By ~ 4

Author(s):

Susan Kadlubar ◽

Fred F. Kadlubar

Keyword(s):

Drug Metabolism ◽

Phase I ◽

Phase Ii ◽

Phase Ii Drug Metabolism

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Evaluation of Active Hexose Correlated Compound (Ahcc) on Phase Ii Drug Metabolism Pathways and the Implications for Supplement-Drug Interactions

Journal of Integrative Oncology ◽

10.4172/2329-6771.1000142 ◽

2015 ◽

Vol 04 (03) ◽

Author(s):

Larry W Coffer Lata Mathew ◽

Xue Zhang Norah A

Keyword(s):

Drug Metabolism ◽

Drug Interactions ◽

Phase Ii ◽

Phase Ii Drug Metabolism

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65 Phase II drug metabolism UGT1A enzyme affects cellular response of colon cancer cells to antitumor triazoloacridinone C-1305 treatment

European Journal of Cancer ◽

10.1016/s0959-8049(14)70191-1 ◽

2014 ◽

Vol 50 ◽

pp. 26

Author(s):

E. Augustin ◽

E. Bartusik ◽

A. Theus ◽

B. Borowa-Mazgaj ◽

Z. Mazerska

Keyword(s):

Colon Cancer ◽

Drug Metabolism ◽

Cancer Cells ◽

Phase Ii ◽

Cellular Response ◽

Colon Cancer Cells ◽

Phase Ii Drug Metabolism

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Diet companied with cold stimulation changed the activity of cytochrome P450 and phase II drug metabolism enzymes in spleen of rats

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2016.10.183 ◽

2017 ◽

Vol 32 (1) ◽

pp. S43

Author(s):

Lijuan Liu ◽

Rui Zhi Zhao

Keyword(s):

Cytochrome P450 ◽

Drug Metabolism ◽

Phase Ii ◽

Cold Stimulation ◽

Metabolism Enzymes ◽

Phase Ii Drug Metabolism

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Screening for phase I and phase II drug metabolism using supplemented liver and intestinal S9 fractions: A cocktail approach

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2018.09.100 ◽

2019 ◽

Vol 34 (1) ◽

pp. S24-S25

Author(s):

Kevin Thomas ◽

Shantanu Roychowdhury ◽

Mitchell Martineau

Keyword(s):

Drug Metabolism ◽

Phase I ◽

Phase Ii ◽

Cocktail Approach ◽

Phase Ii Drug Metabolism

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How to Manage Individualized Drug Therapy: Application of Pharmacogenetic Knowledge of Drug Metabolism and Transport

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm.2000.126 ◽

2000 ◽

Vol 38 (9) ◽

Cited By ~ 20

Author(s):

Christian Meisel ◽

Ivar Roots ◽

Ingolf Cascorbi ◽

Ulrich Brinkmann ◽

Jürgen Brockmöller

Keyword(s):

Drug Therapy ◽

Drug Metabolism ◽

Individualized Drug Therapy

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Characterization of phase I and phase II drug metabolism and the effect of ?-naphthoflavone in the liver and posterior kidney of the channel catfish,Ictalurs punctatus

Archives of Environmental Contamination and Toxicology ◽

10.1007/bf01055170 ◽

1988 ◽

Vol 17 (3) ◽

pp. 325-332 ◽

Cited By ~ 19

Author(s):

Laurence G. Tate

Keyword(s):

Drug Metabolism ◽

Phase I ◽

Phase Ii ◽

Channel Catfish ◽

Phase Ii Drug Metabolism

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