Clinical Efficacy of Dhatryadi Ghanavati in Shvitra (Vitiligo)

Author(s):  
Manjiri Walinjkar ◽  
P.D. Londhe ◽  
S. R. Makhare ◽  
Anil Avhad

Background: Shvitra (vitiligo) is a kind of skin disorder comprising of white coloured skin patches which is considered as a social stigma. Worldwide prevalence of Vitiligo is observed as 1% of the total population. Due to the chronic nature, long term treatment, lack of uniform effective therapy and unpredictable course the disease is usually very demoralizing for patients. Aim: To study the efficacy of ‘Dhatryadi Ghanavati’ in the management of Shvitra. Materials and Methods: Total 50 patients of Shvitra from OPD and IPD unit of Dr. M.N. Agashe Hospital, Satara were selected and provided with Dhatryadi Ghanavati 1gm B.D. for the duration of 3 months. Results: 100% relief was observed in Daha and Kandu followed by 83.33% relief was observed in Rukshata. 34.51% improvement was seen in number of patches, 34.82% in size of patches and 34.29% in percentage area involved. Color of the patches was improved by 69.01% whereas 44% improvement was seen in hair discoloration. Conclusion: The compound formulation ‘Dhatryadi Ghanavati’ was found as an effective remedy for ‘Shvitra’. The parameters like number of patches, size of patches, percentage area involved and colour of patches showed statistically highly significant results.

2019 ◽  
Vol 114 (1) ◽  
pp. S685-S685
Author(s):  
Kevin Woods ◽  
Irene Sarosiek ◽  
Karina Espino ◽  
Marisol Ramirez ◽  
Tariq Siddiqui ◽  
...  

2005 ◽  
pp. 96-100
Author(s):  
T. L. Pashkova ◽  
S. Yu. Chikina ◽  
A. V. Chernyak ◽  
Zh. K. Naumenko ◽  
G. V. Nekludova ◽  
...  

The study was designed to assess clinical efficacy and tolerability of new non-freon aerosol of troventol. The study involved 20 patients (4 males and 16 females) with intermittent or mild persistent stable asthma aged 22 to 67 yrs, the average age, 44.3 ± 11.1 (М ± SD). Anticholinergic effect of troventol was assessed under a single inhalation of the drug (the acute test) which was the 1-st stage of the study, and after long-term (4 wks) treatment which was the 2-nd stage. Clinical efficacy was evaluated by Borg's scoring of cough and dyspnoea, lung and heart auscultation, need in short-acting beta-2-agonists. The acute test included the metacholine challenge test before and 3 hrs after inhalation of 80 mcg of troventol or placebo. The long-term treatment stage included the metacholine challenge test before and in 4 weeks of daily inhalations of 160 mcg of troventol. As a result, the new non-freon aerosol of troventol demonstrated distinct brochodilating and anticholinergic effects which significantly differed from placebo in patients with intermittent or mild persistent stable asthma. Being administered for a long period (4 wks) the drug improved cough and dyspnoea and reduced the need in short-acting beta-agonists while bronchial airflow parameters did not change considerably. There were no adverse events of the therapy during the study.


1996 ◽  
Vol 89 (1) ◽  
pp. 117-126
Author(s):  
Masahiro MORITA ◽  
Tamotsu HARADA ◽  
Manabu TAMURA ◽  
Takeshi KUBO

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