Construction of DNA/RNA Triplex Helices Based on GAA/TTC Trinucleotide Repeats

BIO-PROTOCOL ◽  
2021 ◽  
Vol 11 (18) ◽  
Author(s):  
Jiahui Zhang ◽  
Ashkan Fakharzadeh ◽  
Feng Pan ◽  
Christopher Roland ◽  
Celeste Sagui
Keyword(s):  
Trinucleotide Repeats ◽  
Rna Triplex

A Novel Electrochemical Biosensor Based on a Double-Signal Technique for d(CAG)n Trinucleotide Repeats

2017 ◽  
Vol 9 (50) ◽  
pp. 44231-44240 ◽  
Author(s):  
Jiao Li ◽  
Yalan Liu ◽  
Xiaoqian Zhu ◽  
Gang Chang ◽  
Hanping He ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Trinucleotide Repeats

Trinucleotide repeats and hereditary ataxias

1997 ◽  
Vol 3 (2) ◽  
pp. 149-150 ◽  
Author(s):  
T. Klockgether ◽  
J. Dichgans
Keyword(s):  
Trinucleotide Repeats ◽  
Hereditary Ataxias

scholarly journals Huntington's Disease: An Immune Perspective

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Annapurna Nayak ◽  
Rafia Ansar ◽  
Sunil K. Verma ◽  
Domenico Marco Bonifati ◽  
Uday Kishore
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Neurodegenerative Disorder ◽  
Typical Feature ◽  
Trinucleotide Repeats ◽  
Mutant Huntingtin Protein ◽  
Unexplored Area ◽  
Cag Trinucleotide Repeats ◽  
The Brain ◽  
Abnormal Expansion

Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide repeats. Neuroinflammation is a typical feature of most neurodegenerative diseases that leads to an array of pathological changes within the affected areas in the brain. The neurodegeneration in HD is also caused by aberrant immune response in the presence of aggregated mutant huntingtin protein. The effects of immune activation in HD nervous system are a relatively unexplored area of research. This paper summarises immunological features associated with development and progression of HD.

scholarly journals Homozygous 31 trinucleotide repeats in the SCA2 allele are pathogenic for cerebellar ataxia

2018 ◽  
Vol 4 (6) ◽  
pp. e283 ◽  
Author(s):  
Maya Tojima ◽  
Gaku Murakami ◽  
Rie Hikawa ◽  
Hodaka Yamakado ◽  
Hirofumi Yamashita ◽  
...  
Keyword(s):  
Cerebellar Ataxia ◽  
Trinucleotide Repeats

Direct detection of expanded trinucleotide repeats using PCR and DNA hybridization techniques

1996 ◽  
Vol 67 (1) ◽  
pp. 85-91 ◽  
Author(s):  
Arturas Petronis ◽  
Henry H. Q. Heng ◽  
Yuriy Tatuch ◽  
Xiao-Mei Shi ◽  
Timothy A. Klempan ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Direct Detection ◽  
Trinucleotide Repeats
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