scholarly journals Accelerating the translation of research findings to clinical practice: insights from phantom limb pain clinical trials

2021 ◽  
Vol 7 (4) ◽  
pp. 1-7
Author(s):  
Kevin Pacheco-Barrios ◽  
Paulo Sampaio de Melo ◽  
Karen Vasquez-Avila ◽  
Alejandra Cardenas-Rojas ◽  
Paola Gonzalez-Mego ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Clinical Practice ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain ◽  
Research Findings

scholarly journals Central nervous system stimulation therapies in phantom limb pain: a systematic review of clinical trials

2022 ◽  
Vol 17 (1) ◽  
pp. 59
Author(s):  
Diana Cardona ◽  
MÁngeles Garcia-Pallero ◽  
Lola Rueda-Ruzafa ◽  
Miguel Rodriguez-Arrastia ◽  
Pablo Roman
Keyword(s):  
Systematic Review ◽  
Central Nervous System ◽  
Clinical Trials ◽  
Nervous System ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain ◽  
Central Nervous System Stimulation

scholarly journals Strategies to enhance recruitment methods in phantom limb pain clinical trials

2017 ◽  
Vol 4 (2) ◽  
pp. 72 ◽  
Author(s):  
Camila Bonin Pinto ◽  
Faddi Ghassan Saleh Vélez ◽  
Melanie N. French ◽  
Dian Zeng ◽  
David Crandell ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Large Scale ◽  
Randomized Clinical Trials ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Institutional Review Boards ◽  
Recruitment Strategies ◽  
Limb Pain ◽  
Recruitment Methods ◽  
Institutional Review

<p class="abstract">Phantom limp pain (PLP) was first described in 1551. To date, its mechanisms and novel interventions remain mostly untested. Only limited conclusions can be drawn from few and small sized randomized clinical trials (RCTs) on PLP. In this scenario, enhanced recruitment strategies are crucial in order to overcome inherent challenges to recruit and enroll PLP subjects for clinical trials. Although there are many general methods to enhance recruitment and also retention, in this article we discuss these methods based on a common topic; dissemination. We summarize and discuss ten strategies of recruitment related to the dissemination of information based on the notion that increased trial awareness may lead to both improved recruitment and also external generalizability. In addition, we include insights based on our experience recruiting PLP patients for the purposes of a large-scale and on-going NIH-sponsored clinical trial. Although specific regulatory considerations need to be considered when choosing the methods of recruitment (which may vary across different countries and Institutional Review Boards (IRBs)), these strategies may be applicable to most research settings.</p>

Dealing with pain

2010 ◽  
pp. 5411-5416 ◽  
Author(s):  
Henry McQuay
Keyword(s):  
Neuropathic Pain ◽  
Clinical Practice ◽  
Antiepileptic Drugs ◽  
Phantom Limb Pain ◽  
Nerve Damage ◽  
Phantom Limb ◽  
Nociceptive Pain ◽  
Limb Pain ◽  
Pain Transmission

Pain is complex—it is too simple to view pain transmission as a hard-wired, line-labelled system, because that cannot explain complexities such as phantom limb pain. The crucial mechanistic distinction for clinical practice is between normal (nociceptive) and nerve damage (neuropathic) pain. Types of analgesics—conventional analgesics, from paracetamol through to morphine, work well in nociceptive pain and less well in neuropathic pain. Unconventional analgesics, antidepressants, and antiepileptic drugs work well in neuropathic and less well in nociceptive pain....

Preoperative Modeling Intervention for Phantom Limb Pain

2006 ◽  
Author(s):  
Cheree L. Nichole ◽  
William G. Johnson
Keyword(s):  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain

Cortical reorganization in phantom limb pain changes after regional anesthesia of the amputated limb

1996 ◽  
Author(s):  
P. Montoya ◽  
N. Birbaumer ◽  
W. Lutzenberger ◽  
H. Flor ◽  
W. Grodd ◽  
...  
Keyword(s):  
Regional Anesthesia ◽  
Phantom Limb Pain ◽  
Cortical Reorganization ◽  
Phantom Limb ◽  
Limb Pain

Novel Visual Methods Evoke Phantom Sensations and Treat Phantom Limb Pain

2007 ◽  
Author(s):  
David H. Peterzell ◽  
Roberta E. Cone ◽  
Christian Carter ◽  
Alexandrea Harmell ◽  
Judy Ortega ◽  
...  
Keyword(s):  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Visual Methods ◽  
Limb Pain
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