scholarly journals Bifocal Tuberculosis with Adalimumab Revealed by Laryngeal Involvement: Case Report

2021 ◽  
Vol 28 (1) ◽  
pp. E202117
Author(s):  
Najlae El Ouardi ◽  
Laila Taoubane ◽  
Adil Zegmout ◽  
Marouane Balouki ◽  
Siham Sadni ◽  
...  

Introduction. Anti-TNF treatment has transformed the treatment of chronic inflammatory rheumatism. Although the therapy can be highly effective, anti-TNF drugs are associated with an increased risk of tuberculosis, especially extra-pulmonary tuberculosis. Laryngeal tuberculosis is rare and its symptoms are not specific. Laryngeal tuberculosis is often secondary to another localization, particularly pulmonary. In the use of anti-TNF therapy, its development is unusual. Case report. We report a case of bifocal tuberculosis: laryngeal and pulmonary tuberculosis revealed by laryngeal involvement in a patient aged 41 years with axial spondylarthritis treated with Adalimumab. Conclusion. This presentation highlights the importance to consider the rare possibility of laryngeal tuberculosis in the presence of atypical otorhinolaryngologic signs under anti-TNF therapy and underlines the importance of looking for other tuberculosis involvement.

Author(s):  
Sudhir Shyam Kushwaha ◽  
Garima Maurya ◽  
Kumar Shantanu ◽  
Deepak Kumar

<p class="abstract"><span lang="EN-IN">Tubercular dactylitis is defined as tubercular infection of the metacarpals, metatarsals and phalanges. It is a rare form of extra pulmonary tuberculosis. Bones of the hand are more commonly affected than the bones of the feet. Tubercular dactylitis is common in children and children below 6 year of age accounts for 85% of cases. The diagnosis is usually by a combination of clinical suspicion coupled with radiological investigation and confirmation by biopsy. We hereby present a case report of tubercular dactylitis in a 65 year old female which was treated by antitubercular therapy.</span></p>


1970 ◽  
Vol 29 (1) ◽  
pp. 30-32
Author(s):  
RL Gurubacharya ◽  
SM Gurubacharya

The genitourinary tract is the most common extrapulmonary site affected by tuberculosis. The male genital organs are involved in more than 50% of patients. The epididymis is the commonest structure to be involved, followed by the seminal vesicles, prostate, testis, and the vas deferens. An isolated tuberculous orchitis without epididymal involvement is rare. This case report describes extra pulmonary tuberculosis with exclusively testicular presentation. The confirmatory diagnosis of which was made by FNAC of the testis. It provides a successful diagnosis, thereby preventing unnecessary orchidectomy. Key words: genitourinary tuberculosis, testis, USG, FNAC   doi:10.3126/jnps.v29i1.1598 J. Nepal Paediatr. Soc. Vol.29(1) p.30-32


2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
K. Ibn Majdoub Hassani ◽  
S. Ait Laalim ◽  
I. Toughrai ◽  
K. Mazaz

Extra pulmonary tuberculosis accounts for less than 15% of all cases of tuberculosis whereas the Intestinal one constitutes less than 1% of the extrapulmonary forms of the disease. The lesions of abdominal organs are more common while they rarely occur in the anoperineal area for the spread of the disease to the anus is extremely rare. We report a case of a 37-year-old male patient with large bilateral infected perianal tubercular ulcerations as well as pulmonary and peritoneal tuberculosis. The treatment was both surgical and medical and the therapy lasted for seven months. After six months from the beginning of the treatment, the lesion had totally disappeared and there is still no recurrence after one year of followup. Tuberculosis should generally be taken into consideration in the differential diagnosis of the ulcerative lesions of the anal and perianal regions for these lesions do occur in the said areas despite their rarity. The treatment is usually both surgical and medical so as to get excellent results.


Author(s):  
Abubakar Tukur Dawakin KUDU ◽  
Sami ILİYA ◽  
Akinfenwa Taofeq ATANDA ◽  
Nasiru Abdullahi ISMAİL ◽  
Abdurrahaman Abba SHEHE

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