scholarly journals Peyronie's disease and the first user experience of Peyroflex®

2021 ◽  
Vol 9 (2) ◽  
pp. 150-156
Author(s):  
G. V. Shirin ◽  
N. A. Fedorova

The article deals with the current issues of the etiology, pathogenesis and clinical course of Peyronie's disease. The diagnostic possibilities of using ultrasound sonography are demonstrated. The international data on known treatment options for Peyronie's disease are reviewed. The author describes his own user experience of the Peyroflex® at an early stage of the disease and gives a preliminary assessment of its effectiveness.

2021 ◽  
Vol 11 (3) ◽  
pp. 209-219
Author(s):  
V. N. Pavlov ◽  
A. A. Bakirov ◽  
R. A. Kazikhinurov ◽  
A. A. Kazikhinurov ◽  
M. A. Agaverdiev ◽  
...  

Corporoplasty is urological correction surgery for penile deviation that causes copulatory dysfunction or aesthetic discomfort. Penile deviation can be congenital or acquired (Peyronie’s disease, penile fracture). Congenital penile deviation is relatively rare and manifests in the curvature of erect penis ventrally and/or laterally, in most cases. According to many studies, patients with curvatures of 30° or more eventually seek surgical treatment. Congenital curvature may be mistaken for Peyronie’s disease for similar manifestations that, however, differ in aetiology and pathophysiology. Excisional, incisional corporoplasty or plication are commonly engaged to treat congenital curvatures, in various techniques and modifications. Augmentation transplantation (grafting) and penile prosthesis implantation with variant deviation treatment options are the usual practice in Peyronie’s disease. Unequivocal judgment of pros and cons in any particular technique is nevertheless implausible to make. This article aims to review current trends, protocols and their relative advantages in corporoplasty.


2009 ◽  
Vol 9 ◽  
pp. 665-675 ◽  
Author(s):  
Michael R. Abern ◽  
Laurence A. Levine

The purpose of our study was to outline the evaluation of the Peyronie's disease (PD) patient and review the available nonsurgical treatments. A review of the literature on oral, intralesional, external energy, iontophoresis, and mechanical therapies for PD was performed. PubMed was utilized to find all published articles, and several meeting abstracts were reviewed for data ahead of publication. Our medical evaluation of the PD patient is described. The published results of available treatment options are reviewed, with recommendation by the authors for appropriate nonsurgical management of PD. There are no available validated questionnaires for PD, but a thorough history and focused physical examination, including measurement of erect penile deformity, will help the clinician make the diagnosis and guide treatment options. Although there are many published reports that show efficacy of nonsurgical therapies for PD, there is a lack of large-scale, multicenter, controlled clinical trials, which makes treatment recommendations difficult. Careful review of the literature does suggest that there are treatment options that make scientific sense and appear to stabilize the disease process, reduce deformity, and improve function. Offering no treatment at all will encourage our patients to pursue alternative treatments that may do harm, and misses the opportunity to do some good. Clearly, further work is necessary to develop safe and effective nonsurgical treatments for PD.


Author(s):  
Mohammed Abdel Malek Hasan ◽  
Ehab Rifaat Tawfik ◽  
Alayman Fathy Hussien ◽  
Adel Mohammed Ali Salheen

2020 ◽  
Vol 17 (2) ◽  
pp. 87-96
Author(s):  
Md Abul Hossain ◽  
Md Waliul Islam ◽  
Md Nurul Hooda ◽  
Md Fazal Naser ◽  
Md Shohrab Hossain ◽  
...  

Objective: To assess the articles published on current treatments for Peyronie’s disease (PD) and it’s new development and to assist clinicians to select the effective management of PD by increasing understanding and awareness of the outcomes associated with current medical and surgical treatment options. Methods: A Hinari literature search was conducted to identify relevant, peer-reviewed, clinical and review articles published related to current treatment options and it’s new developments of Peyronie’s Disease. Search terms for this non-systematic review included ‘Peyronie’s disease’, ‘current treatment, outcomes’, new development. ‘Erectile dysfunction or ED’, search terms were searched separately and in combination. Case studies and editorials were excluded, primary manuscripts and reviews were included, and references of articles of interest were reviewed and key references were obtained. Result: Currently, there are several investigational minimally invasive and non-surgical treatment options for PD; however, surgical treatment remains the standard of care for patients with stable disease and disabling deformity or drug-resistant erectile dysfunction. Each of the different surgical procedures that are used for treatment of PD, including tunical shortening, tunical lengthening (plaque incisions or partial excision and grafting), and use of inflatable penile prostheses, carries its own advantages and disadvantages in terms of potential complications and postoperative satisfaction. No single, standard, surgical treatment for this disorder has prevailed and multiple variations of each type of procedure exist. Obtaining data on current treatment and its modifications to these procedures, and new surgical techniques and materials may serve to further guide Conclusion: The real etiology of Peyronie’s disease and the mechanisms of formation of the plaque still remain obscure. Although conservative management is obtaining a progressively larger consensus among the experts, surgical correction still remains the mainstay treatment for this condition. Treatment should be tailored to each patient after a detailed evaluation of disease severity and sexual function. Bangladesh Journal of Urology, Vol. 17, No. 2, July 2014 p.87-96


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