scholarly journals Capillary zone electrophoretic determination of 5-hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluid from patients with neuropsychiatric disorders.

1996 ◽  
Vol 40 (4) ◽  
pp. 193-197
Author(s):  
Atsushi Hiraoka ◽  
Teruyo Arato ◽  
Itaru Tominaga
Keyword(s):  
Cerebrospinal Fluid ◽  
Homovanillic Acid ◽  
Neuropsychiatric Disorders ◽  
Hydroxyindoleacetic Acid ◽  
Capillary Zone

Difficulties in establishing reference intervals for special fluids: the example of 5-hydroxyindoleacetic acid and homovanillic acid in cerebrospinal fluids

2004 ◽  
Vol 42 (7) ◽  
Author(s):  
Jean-Louis Dhondt
Keyword(s):  
Cerebrospinal Fluid ◽  
Homovanillic Acid ◽  
Reference Interval ◽  
Reference Intervals ◽  
Control Group ◽  
Age Related ◽  
Wide Range ◽  
Hydroxyindoleacetic Acid ◽  
Biochemical Measurements

AbstractBiochemical measurements in “special fluids” are complicated with the problem of reference intervals. Reference intervals are difficult to establish for these types of samples since they are usually only collected in patients with clinical suspicion of disease. Determination of neurotransmitter metabolites in cerebrospinal fluid illustrates this difficulty. This paper will review the factors and circumstances that have been identified or are suspected to modifythe concentration of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in cerebrospinal fluid. In addition to obvious parameters such as age-related variation that can affect the concentration of 5-HIAA and HVA in cerebrospinal fluid, a varietyof other factors can explain the wide range of “control” group sizes reported in the literature. Reference intervals must take into account the purpose of cerebrospinal fluid examinations, whether they be prospective studies to explore physio-pathologic relationships or for diagnostic purposes. In the latter case, certain neurological disorders cannot be excluded if a single measured value is within the reference interval.

Determination of homovanillic acid, 5-hydroxyindoleacetic acid and pressure in the cerebrospinal fluid of Collie dogs following administration of ivermectin

1989 ◽  
Vol 13 (1) ◽  
pp. 47-55 ◽  
Author(s):  
D. M. Vaughn ◽  
S. T. Simpson ◽  
B. L. Blagburn ◽  
W. L. Whitmer ◽  
R. Heddens-Mysinger ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Homovanillic Acid ◽  
Hydroxyindoleacetic Acid
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