scholarly journals Preference-Based Instrumental Variable Methods for the Estimation of Treatment Effects: Assessing Validity and Interpreting Results

Author(s):  
M. Alan Brookhart ◽  
Sebastian Schneeweiss
2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Charles H Mullin

AbstractEmpirical researchers commonly invoke instrumental variable (IV) assumptions to identify treatment effects. This paper considers what can be learned under two specific violations of those assumptions: contaminated and corrupted data. Either of these violations prevents point identification, but sharp bounds of the treatment effect remain feasible. In an applied example, random miscarriages are an IV for women’s age at first birth. However, the inability to separate random miscarriages from behaviorally induced miscarriages (those caused by smoking and drinking) results in a contaminated sample. Furthermore, censored child outcomes produce a corrupted sample. Despite these limitations, the bounds demonstrate that delaying the age at first birth for the current population of non-black teenage mothers reduces their first-born child’s well-being.


2011 ◽  
Vol 19 (2) ◽  
pp. 205-226 ◽  
Author(s):  
Kevin M. Esterling ◽  
Michael A. Neblo ◽  
David M. J. Lazer

If ignored, noncompliance with a treatment or nonresponse on outcome measures can bias estimates of treatment effects in a randomized experiment. To identify and estimate causal treatment effects in the case where compliance and response depend on unobservables, we propose the parametric generalized endogenous treatment (GET) model. GET incorporates behavioral responses within an experiment to measure each subject's latent compliance type and identifies causal effects via principal stratification. Using simulation methods and an application to field experimental data, we show GET has a dramatically lower mean squared error for treatment effect estimates than existing approaches to principal stratification that impute, rather than measure, compliance type. In addition, we show that GET allows one to relax and test the instrumental variable exclusion restriction assumption, to test for the presence of treatment effect heterogeneity across a range of compliance types, and to test for treatment ignorability when treatment and control samples are balanced on observable covariates.


2008 ◽  
Vol 169 (3) ◽  
pp. 273-284 ◽  
Author(s):  
J. A. Rassen ◽  
S. Schneeweiss ◽  
R. J. Glynn ◽  
M. A. Mittleman ◽  
M. A. Brookhart

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Martin Huber ◽  
Kaspar Wüthrich

Abstract This paper provides a review of methodological advancements in the evaluation of heterogeneous treatment effect models based on instrumental variable (IV) methods. We focus on models that achieve identification by assuming monotonicity of the treatment in the IV and analyze local average and quantile treatment effects for the subpopulation of compliers. We start with a comprehensive discussion of the binary treatment and binary IV case as for instance relevant in randomized experiments with imperfect compliance. We then review extensions to identification and estimation with covariates, multi-valued and multiple treatments and instruments, outcome attrition and measurement error, and the identification of direct and indirect treatment effects, among others. We also discuss testable implications and possible relaxations of the IV assumptions, approaches to extrapolate from local to global treatment effects, and the relationship to other IV approaches.


2021 ◽  
pp. 1-23
Author(s):  
Hiroyuki Kasahara ◽  
Katsumi Shimotsu

We study identification in nonparametric regression models with a misclassified and endogenous binary regressor when an instrument is correlated with misclassification error. We show that the regression function is nonparametrically identified if one binary instrument variable and one binary covariate satisfy the following conditions. The instrumental variable corrects endogeneity; the instrumental variable must be correlated with the unobserved true underlying binary variable, must be uncorrelated with the error term in the outcome equation, but is allowed to be correlated with the misclassification error. The covariate corrects misclassification; this variable can be one of the regressors in the outcome equation, must be correlated with the unobserved true underlying binary variable, and must be uncorrelated with the misclassification error. We also propose a mixture-based framework for modeling unobserved heterogeneous treatment effects with a misclassified and endogenous binary regressor and show that treatment effects can be identified if the true treatment effect is related to an observed regressor and another observable variable.


2016 ◽  
Vol 33 (1) ◽  
pp. 69-104 ◽  
Author(s):  
Karim Chalak

We study the consequences of substituting an error-laden proxy W for an instrument Z on the interpretation of Wald, local instrumental variable (LIV), and instrumental variable (IV) estimands in an ordered discrete choice structural system with heterogeneity. A proxy W need only satisfy an exclusion restriction and that the treatment and outcome are mean independent from W given Z. Unlike Z, W need not satisfy monotonicity and may, under particular specifications, fail exogeneity. For example, W could code Z with error, with missing observations, or coarsely. We show that Wald, LIV, and IV estimands using W identify weighted averages of local or marginal treatment effects (LATEs or MTEs). We study a necessary and sufficient condition for nonnegative weights. Further, we study a condition under which the Wald or LIV estimand using W identifies the same LATE or MTE that would have been recovered had Z been observed. For example, this holds for binary Z and therefore the Wald estimand using W identifies the same “average causal response,” or LATE for binary treatment, that would have been recovered using Z. Also, under this condition, LIV using W can be used to identify MTE and average treatment effects for e.g., the population, treated, and untreated.


2017 ◽  
Vol 34 (1) ◽  
pp. 112-133 ◽  
Author(s):  
Tymon Słoczyński ◽  
Jeffrey M. Wooldridge

In this paper we study doubly robust estimators of various average and quantile treatment effects under unconfoundedness; we also consider an application to a setting with an instrumental variable. We unify and extend much of the recent literature by providing a very general identification result which covers binary and multi-valued treatments; unnormalized and normalized weighting; and both inverse-probability weighted (IPW) and doubly robust estimators. We also allow for subpopulation-specific average treatment effects where subpopulations can be based on covariate values in an arbitrary way. Similar to Wooldridge (2007), we then discuss estimation of the conditional mean using quasi-log likelihoods (QLL) from the linear exponential family.


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