THE COOPERATIVE CLINICAL RESEARCH PROGRAM OF THE NATIONAL CANCER INSTITUTE

1970 ◽  
Vol 108 (1) ◽  
pp. 14-18
Author(s):  
LAURANCE V. FOYE
JAMA ◽  
2011 ◽  
Vol 305 (4) ◽  
pp. 348
Author(s):  
Bridget M. Kuehn

1986 ◽  
Vol 28 (10) ◽  
pp. 902-905
Author(s):  
William D. DeWys ◽  
Richard D. Costlow ◽  
Winfred F. Malone

Author(s):  
Jennifer L. Ersek ◽  
Stephanie L. Graff ◽  
Francis P. Arena ◽  
Neelima Denduluri ◽  
Edward S. Kim

Increasing enrollment into clinical trials is a top priority across the field of oncology. Because the vast majority of those afflicted with cancer receive their care in the community, creating strong clinical research programs in the community-based setting is important. This article comprehensively outlines the most important elements of creating and sustaining a successful community-based research program. Establishing a clear mission and defining the scope of the research program in collaboration with key physicians and administrative leadership are critical to success. Standard operating procedures should detail operational processes. Ensuring sound financial planning and protected physician time are crucial for a healthy program. Providing mentorship opportunities to investigators and other team members will provide necessary guidance for junior investigators and long-term program stability. Prioritizing provider and patient volunteer engagement through education and awareness will potentially improve enrollment and research ownership. Incorporating administrative and clinical research staff and health care providers, including physicians, advanced practice providers, and pharmacists, will result in a multidisciplinary and unified approach and may also promote research as a routine part of patient care. Regular safety and scientific meetings will reduce regulatory complications and, most importantly, improve patient care. Other keys to a successful program include establishing a diverse trial portfolio, collaboration between different institutions, and ensuring appropriate technological infrastructure. Serial programmatic review provides opportunities to refine suboptimal practices and recognize successful strategies. Community-based research programs are critical to improve access to optimal cancer care. Implementation of successful programs is possible with a collaborative and multidisciplinary approach.


2019 ◽  
Vol 112 (6) ◽  
pp. 557-561 ◽  
Author(s):  
Ann M Geiger ◽  
Ann M O’Mara ◽  
Worta J McCaskill-Stevens ◽  
Brenda Adjei ◽  
Priyanga Tuovenin ◽  
...  

Abstract Research seeking to improve patient engagement with decision-making, use of evidence-based guidelines, and coordination of multi-specialty care has made important contributions to the decades-long effort to improve cancer care. The National Cancer Institute expanded support for these efforts by including cancer care delivery research in the 2014 formation of the National Cancer Institute Community Oncology Research Program (NCORP). Cancer care delivery research is a multi-disciplinary effort to generate evidence-based practice change that improves clinical outcomes and patient well-being. NCORP scientists and community-based clinicians and organizations rapidly embraced the addition of this type of research into the network, resulting in a robust portfolio of observational studies and intervention studies within the first 5 years of funding. This commentary describes the initial considerations in conducting this type of research in a network previously focused on cancer prevention, control, and treatment studies; characterizes the protocols developed to date; and outlines future directions for cancer care delivery research in the second round of NCORP funding.


Cancer ◽  
2008 ◽  
Vol 113 (12) ◽  
pp. 3391-3399 ◽  
Author(s):  
Karen M. Freund ◽  
Tracy A. Battaglia ◽  
Elizabeth Calhoun ◽  
Donald J. Dudley ◽  
Kevin Fiscella ◽  
...  

Cancer ◽  
2020 ◽  
Author(s):  
Chandylen L. Nightingale ◽  
Katherine R. Sterba ◽  
Laurie E. McLouth ◽  
Erin E. Kent ◽  
Emily V. Dressler ◽  
...  

1997 ◽  
Vol 72 (10) ◽  
pp. 901-912 ◽  
Author(s):  
John P. Chute ◽  
David J. Venzon ◽  
Lynn Hankins ◽  
Paul Okunieff ◽  
James N. Frame ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document