Assessment of the Haematological Alterations in Cervical Cancer Patients Attending Sabratha

Background: Cervix cancer is one of the most common cancers in women worldwide, and is the third most common malignant disease in women. It is one of the main health problems in Libyan women. Blood act as a pathological reflector of the status of exposed patient to infections and other conditions. Laboratory tests on the blood are vital tools that help detect any deviation from normal in the human body As the disease progresses, changes appear in haematological parameters which have been of relevant consideration in context of cancer patients. Objectives: The present study aimed to evaluate the alterations in haematological parameters among cervical cancer patients in Sabratha National Cancer Institute. Subjects and Methods: The present study was conducted on 150 cervical cancer patients, attending the National Cancer Institute of Sabratha from the 11th February, 2006 to the 3rd February, 2020. This study was approved by the Research and Ethical Committee of Sabratha University and Sabratha National Cancer Institute. Age was extracted from patient files. Also, 60 healthy individuals without any chronic disease were recruited for the control group. Blood samples were collected by vein puncture, 3 ml of venous blood withdrawn from each participant in the study by using disposable syringes under aseptic technique; they then transferred to a sterile EDTA tube, for complete blood count. The statistical significance of differences between groups was evaluated with the Mann Whitney U test. Results: The results showed that the mean age of the cervix cancer patients was 53.37±11.6 years.RBCs count, hemoglobin concentration, Hct value, MCH, MCHC, and lymphocytes % were significantly (P<0.01) decreased compared with the healthy individuals. On the other hand, leukocytes and platelets count, mixed %, neutrophils %, PLTs/Lymph, and Neutrophils/Lymphocytes ratios were significantly increased as compared with the healthy individuals. Conclusion: It can be concluded that a significant increase in leukocytes and platelets count, mixed %, neutrophils %, and the studied inflammation related haematological parameters and a significant decreased in lymphocytes %, RBCs count and most its indices. Further haematological studies are needed to confirm these results. Also, there is need to routinely monitor the haematological parameters and among cervical cancer patients.

“THE STUDY TO ASSESS AN INCIDENCE OF FEVER IN POST-OPERATIVE PATIENTS ADMITTED IN SURGICAL ICU AT NATIONAL CANCER INSTITUTE, DHARAMPETH, NAGPUR.”

INTRODUCTION: Postoperative fever is one of the most common problems seen in the postoperative ward. Most cases of fever immediately following surgery are self-limiting. The appearance of postoperative fever is not limited to specic types of surgery. Fever can occur immediately after surgery and seen to be related directly to the operation or may occur sometime after the surgery as a result of an infection at the surgical site or infections that involve organs distant from the surgery. Objectives: To study the common causes of post operative fever in general surgery patients. To study the correlation between the cause and the day of onset of fever. To study the risk factors associated with post operative fever. Material and Method: In this study Descriptive Research Design was used. The samples were 30 Post operative patients which fulls inclusion criteria. Setting of the study was surgical ICU, National cancer Institute, Dharampeth, Nagpur. RESULTS:-The result of this study shows that There 6 patients in the age group of 41yrs to 60 yrs having increase WBC count. Fisher exact test statistic value is 0.0449. The result is signicant at p < .05. so the post operative fever is signicantly associated with gender of the patient, Types of surgery and increase WBC count in Patient.

Survivorship for Individuals Living with Advanced and Metastatic Cancers: National Cancer Institute Meeting Report

An important and often overlooked subpopulation of cancer survivors is individuals who are diagnosed with or progress to advanced or metastatic cancer. Living longer with advanced or metastatic cancer often comes with a cost of burdensome physical and psychosocial symptoms and complex care needs, however research is limited on this population. Thus, in May 2021, the National Cancer Institute convened subject matter experts, researchers, clinicians, survivors, and advocates a for a 2-day virtual meeting. The purpose of this report is to provide a summary of the evidence gaps identified by subject matter experts and attendees and key opportunities identified by NCI in five research areas: epidemiology and surveillance, symptom management, psychosocial research, healthcare delivery, and health behaviors. Identified gaps and opportunities include the need to develop new strategies to estimate the number of individuals living with advanced and metastatic cancers, understand and address emerging symptom trajectories, improve prognostic understanding and communication between providers, patients, and caregivers, develop and test models of comprehensive survivorship care tailored to these populations, and assess patient and provider preferences for health behavior discussions throughout the survivorship trajectory. To best address the needs of individuals living with advanced and metastatic cancer and to deliver comprehensive evidence-based quality care, research is urgently needed to fill evidence gaps, and it is essential to incorporate the survivor perspective. Developing such an evidence base is critical to inform policy and practice.

PROFILE OF ESOPHAGUS NEOPLASMS RELATED TO THE CONSUMPTION OF ALCOHOLIC BEVERAGES:

Introduction: Esophageal neoplasia presents a high morbidity and mortality rate, associated with males and the esolist habit. Objective: to describe the profile of esophageal neoplasia related to alcohol consumption between 2015 and 2019 in Montes Claros, Minas Gerais, Brazil. Methods: A descriptive study of quantitative approach was conducted through data from patients diagnosed with esophageal neoplasia in hospital records of the José Alencar Gomes da Silva National Cancer Institute (INCA). Results and discussion: 525 cases of esophageal neoplasia were recorded in the period evaluated. Alcohol consumption was positive in 88.1% of the cases. Conclusion: The data indicate a positive relationship between alcohol consumption and esophageal neoplasia. These data should encourage the establishment of public policies for health education measures in relation to alcohol consumption and smoking habits.

UTERUS CANCER PROFILE IN WOMEN RESIDENTS IN MONTES CLEAR, MINAS GERAIS

Introduction: Cervical cancer is one of the most frequent in the female population, it is related to HPV infection, multiple partners, unfavorable socioeconomic conditions, among other factors. Objective: To know the profile of cervical cancer in women living in Montes Claros, Minas Gerais, Brazil. Methods: This is a descriptive study with a quantitative approach using data from patients diagnosed with cervical cancer available in hospital records of the José Alencar Gomes da Silva National Cancer Institute (INCA). Results and discussion: In the period analyzed, 555 cervical cancer diagnoses were registered in the database of the José Alencar Gomes da Silva National Cancer Institute (INCA) in the municipality investigated. Conclusion: The data available in the INCA database in relation to women residing in Montes Claros, Minas Gerais indicated adult, married, brown women, with a low level of education and occupations with low wages. Coordinated actions from all public spheres of planning and execution of women's health policy are needed to intensify early diagnosis and treatment.

PENIS CANCER PROFILE IN PATIENTS RESIDENT IN MINAS GERAIS

Introduction: Penile cancer are rare neoplasms, being more frequent in men aged 50 years or older, although it may affect men of any age. Unfavorable socioeconomic conditions, poor intimate hygiene, HPV infections, among others, are risk factors for this type of cancer. Objective: To know the profile of penile cancer in patients living in the state of Minas Gerais, Brazil. Methods: A descriptive study of quantitative approach was conducted through data from patients diagnosed with penile cancer in hospital records of the José Alencar Gomes da Silva National Cancer Institute (INCA). Results and discussion: In the period from 2015 to 2019, 573 diagnoses of penile cancer were recorded in the database of the José Alencar Gomes da Silva National Cancer Institute (INCA). Conclusion: Men aged between 50 and 74 years, married, brown and with incomplete high school were identified, the main occupation was agricultural worker. It is essential that in order to face this problem, men's health is considered routinely and systematically in the routine health services.

FEATURES OF ANESTHESIA DURING SURGERY FOR TRACHEAL CANCER

Tracheal neoplasms are rare, accounting for 0.10.2% of all malignant neoplasms [I.I. Davydovskyi, 1940]. Data from the database of the National Cancer Institute for Surveillance, Epidemiology and End Results indicate that primary tracheal carcinomas occur with an incidence of 0.7% of new cases per million people [Houston, 1963]. Patients with tracheal tumors can have severe airway obstruction. In addition to primary tracheal neoplasms, secondary tracheal affection may occur due to lesion of surrounding tissues such as thyroid, larynx, and lungs - 15.3%.