Diffusion-weighted MR imaging in acute stroke: theoretic considerations and clinical applications.

Diffusion weighted imaging (DWI) allows the measurement of molecular motion in tissue. This technique has significant clinical applications. Recent technological developments in fast MR imaging have brought diffusion imaging into clinical practice. This review will explain the physical principles, and current and future potential applications of diffusion imaging in medicine.

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Imaging funzionale per diffusione (DWI) e ischemia cerebrale in fase acuta: Potenzialità diagnostiche e confronto con metodiche convenzionali

Rivista di Neuroradiologia ◽

10.1177/19714009970100s217 ◽

1997 ◽

Vol 10 (2_suppl) ◽

pp. 47-50 ◽

Cited By ~ 1

Author(s):

G. Sparacia ◽

R.G. Gonzalez ◽

F. Buonanno ◽

A.G. Sorensen ◽

R. Lagalla ◽

...

Keyword(s):

Mr Imaging ◽

Acute Stroke ◽

Therapeutic Window ◽

The Third ◽

Diffusion Weighted ◽

Neuroprotective Treatment ◽

Ischemia Cerebrale ◽

Parenchymal Abnormalities ◽

Acute Event

Stroke is the third leading cause of death and is a major cause of long-term disability. Neuroprotective treatment within a 4-hour «therapeutic window» has proved highly efficacious in reducing morbility and mortality in animal model. It is with this background that the need for emergent diagnosis and therapy of acute stroke in strongly suggested. Computed tomography (CT) shows the parenchymal changes of acute stroke too late to be helpful, and its role has been primarily to evaluate the possibility of intracerebral or subarachnoid hemorrhage. While conventional magnetic resonance (MR) imaging can demonstrate parenchymal abnormalities 4–6 hours after ischemia, newer techniques such as diffusion-weighted MR imaging (DWI) hold promise that a diagnosis of ischemia can be made within minutes after the acute event. In this article compares different aspects of hyperacute cerebral ischemia depicted at diffusion-weighted imaging before infarction is depicted at conventional MR or CT scans. DWI techniques may improve stroke diagnosis and may contribute to advances in treatment.

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MR Imaging in Acute Stroke: Diffusion-weighted and Perfusion Imaging Parameters for Predicting Infarct Size

Radiology ◽

10.1148/radiol.2222001731 ◽

2002 ◽

Vol 222 (2) ◽

pp. 397-403 ◽

Cited By ~ 81

Author(s):

Hans-Jörg Wittsack ◽

Afra Ritzl ◽

Gereon R. Fink ◽

Frank Wenserski ◽

Mario Siebler ◽

...

Keyword(s):

Mr Imaging ◽

Infarct Size ◽

Acute Stroke ◽

Perfusion Imaging ◽

Imaging Parameters ◽

Diffusion Weighted

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Clinical applications of diffusion weighted MR imaging: A review

Indian Journal of Radiology and Imaging ◽

10.4103/0971-3026.32328 ◽

2006 ◽

Vol 16 (4) ◽

pp. 705 ◽

Cited By ~ 9

Author(s):

R Rajeshkannan ◽

S Moorthy ◽

KP Sreekumar ◽

R Rupa ◽

NK Prabhu

Keyword(s):

Mr Imaging ◽

Clinical Applications ◽

Diffusion Weighted

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Diffusion-weighted imaging in hyperacute stroke – gold standard?

Acta Radiologica ◽

10.1080/j.1600-0455.2003.00112.x ◽

2003 ◽

Vol 44 (5) ◽

pp. 547-549 ◽

Cited By ~ 1

Author(s):

Y.-Y. Wong ◽

W. W.-M. Lam

Keyword(s):

Case Report ◽

Cerebral Ischemia ◽

Mr Imaging ◽

Acute Stroke ◽

Gold Standard ◽

Diffusion Weighted Imaging ◽

Hyperacute Stroke ◽

Diffusion Weighted ◽

Negative Diffusion

Diffusion-weighted imaging (DWI) is more sensitive than CT and conventional T2-weighted MR imaging in the detection of early cerebral ischemia and infarction. In this case report, we present a case of a 79-year-old woman with symptoms of acute stroke, clinically and radiologically documented progression to complete stroke with an initial negative diffusion-weighted scan.

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