Pelaksanaan Skrining Prakonsepsi pada Calon Pengantin Perempuan

Eka Vicky Yulivantina; Mufdlilah Mufdlilah; Herlin Fitriana Kurniawati

doi:10.22146/jkr.55481

Pelaksanaan Skrining Prakonsepsi pada Calon Pengantin Perempuan

Jurnal Kesehatan Reproduksi ◽

10.22146/jkr.55481 ◽

2021 ◽

Vol 8 (1) ◽

pp. 47

Author(s):

Eka Vicky Yulivantina ◽

Mufdlilah Mufdlilah ◽

Herlin Fitriana Kurniawati

Keyword(s):

Tetanus Toxoid

Latar Belakang: Kesehatan prakonsepsi merupakan bagian dari kesehatan secara keseluruhan antara perempuan dan laki-laki selama masa reproduksinya. Skrining prakonsepsi berguna untuk mengurangi resiko dan mempromosikan gaya hidup sehat untuk mempersiapkan kehamilan sehat.Tujuan: Untuk mengeksplorasi pelaksanaan skrining prakonsepsi pada calon pengantin perempuan.Metode: Penelitian kualitatif dengan pendekatan fenomenologi.Hasil dan Pembahasan: Pelaksanaan skrining prakonsepsi pada calon pengantin perempuan terdiri dari pemeriksaan fisik, pemeriksaan penunjang berupa pemeriksaan laboratorium wajib dan rekomendasi, pemberian imunisasi Tetanus Toxoid, suplementasi gizi, konsultasi kesehatan dan pelayanan psikologi.Kesimpulan: Pelaksanaan skrining prakonsepsi sudah mengacu pada standar minimal. Kata Kunci: Calon pengantin perempuan; skrining prakonsepsi

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Delayed hypersensitivity to tetanus toxoid in man: in vivo and in vitro studies

Pathology ◽

10.3109/00313028309085161 ◽

1983 ◽

Vol 15 (4) ◽

pp. 369-372 ◽

Cited By ~ 15

Author(s):

Christine Johnson ◽

R.S. Walls ◽

A. Ruwoldt

Keyword(s):

Tetanus Toxoid ◽

In Vitro Studies ◽

Delayed Hypersensitivity

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The adjuvant effects of a tubercle bacillary lipid and lecithin: The immunization of mice by tetanus toxoid

Pathology ◽

10.3109/00313027009081209 ◽

1970 ◽

Vol 2 (3) ◽

pp. 209-216 ◽

Cited By ~ 3

Author(s):

A.W. Pound

Keyword(s):

Tetanus Toxoid ◽

Adjuvant Effects

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Faculty Opinions recommendation of Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725387509.793509388 ◽

2015 ◽

Author(s):

Joyce Solheim

Keyword(s):

Dendritic Cell ◽

Tetanus Toxoid ◽

Dendritic Cell Vaccines

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Stimulation of Cynomolgus Peripheral Blood Lymphocytes With Tetanus Toxoid and Smallpox Vaccine

Journal of Medical Primatology ◽

10.1111/j.1600-0684.1983.tb00072.x ◽

1983 ◽

Vol 12 (4) ◽

pp. 192-200 ◽

Cited By ~ 2

Author(s):

H.G. Loggen ◽

J.L. Baerends‐Verburg ◽

J.G. Kreeftenberg

Keyword(s):

Tetanus Toxoid ◽

Peripheral Blood ◽

Peripheral Blood Lymphocytes ◽

Smallpox Vaccine ◽

Blood Lymphocytes ◽

Stimulation Of

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The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced AmyloidβBinding Antibodies on Cynomolgus Monkeys and Guinea Pigs

Journal of Immunology Research ◽

10.1155/2015/786501 ◽

2015 ◽

Vol 2015 ◽

pp. 1-9 ◽

Cited By ~ 1

Author(s):

Akira Yano ◽

Kaori Ito ◽

Yoshikatsu Miwa ◽

Yoshito Kanazawa ◽

Akiko Chiba ◽

...

Keyword(s):

Immune Responses ◽

Tetanus Toxoid ◽

Guinea Pigs ◽

Peptide Vaccine ◽

Cell Epitope ◽

T Cell Epitope ◽

Peptide Vaccination ◽

Binding Profile ◽

Cynomolgus Monkeys ◽

The Brain

The reduction of brain amyloid beta (Aβ) peptides by anti-Aβantibodies is one of the possible therapies for Alzheimer’s disease. We previously reported that the Aβpeptide vaccine including the T-cell epitope of diphtheria-tetanus combined toxoid (DT) induced anti-Aβantibodies, and the prior immunization with conventional DT vaccine enhanced the immunogenicity of the peptide. Cynomolgus monkeys were given the peptide vaccine subcutaneously in combination with the prior DT vaccination. Vaccination with a similar regimen was also performed on guinea pigs. The peptide vaccine induced anti-Aβantibodies in cynomolgus monkeys and guinea pigs without chemical adjuvants, and excessive immune responses were not observed. Those antibodies could preferentially recognize Aβ40, and Aβ42compared to Aβfibrils. The levels of serum anti-Aβantibodies and plasma Aβpeptides increased in both animals and decreased the brain Aβ40level of guinea pigs. The peptide vaccine could induce a similar binding profile of anti-Aβantibodies in cynomolgus monkeys and guinea pigs. The peptide vaccination could be expected to reduce the brain Aβpeptides and their toxic effects via clearance of Aβpeptides by generated antibodies.

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