Guidelines for the management of hospital-acquired pneumonia

2013 ◽  
pp. 80-93
Author(s):  
Adamantia Liapikou
Keyword(s):  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

Etiology of hospital-acquired pneumonia in patients with complicated cervical spine injury. A retrospective study

2020 ◽  
pp. 104-114
Author(s):  
S.A. Pervukhin ◽  
E.A. Filichkina ◽  
I.A. Statcenko ◽  
A.V. Palmash ◽  
I.V. Vitkovskaya ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Retrospective Study ◽  
Cervical Spine Injury ◽  
Spine Injury ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

scholarly journals In Vitro Activity of Doripenem, a Carbapenem for the Treatment of Challenging Infections Caused by Gram-Negative Bacteria, against Recent Clinical Isolates from the United States

2008 ◽  
Vol 52 (12) ◽  
pp. 4388-4399 ◽  
Author(s):  
Chris M. Pillar ◽  
Mohana K. Torres ◽  
Nina P. Brown ◽  
Dineshchandra Shah ◽  
Daniel F. Sahm
Keyword(s):  
The United States ◽  
Clinical Isolates ◽  
Gram Negative Bacteria ◽  
Ventilator Associated Pneumonia ◽  
Coagulase Negative Staphylococci ◽  
Hospital Acquired Pneumonia ◽  
Abdominal Infections ◽  
Hospital Acquired ◽  
Gram Positive Cocci

ABSTRACT Doripenem, a 1β-methylcarbapenem, is a broad-spectrum antibiotic approved for the treatment of complicated urinary tract and complicated intra-abdominal infections. An indication for hospital-acquired pneumonia including ventilator-associated pneumonia is pending. The current study examined the activity of doripenem against recent clinical isolates for the purposes of its ongoing clinical development and future longitudinal analysis. Doripenem and comparators were tested against 12,581 U.S. clinical isolates collected between 2005 and 2006 including isolates of Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus pneumoniae, Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter spp. MICs (μg/ml) were established by broth microdilution. By MIC90, doripenem was comparable to imipenem and meropenem in activity against S. aureus (methicillin susceptible, 0.06; resistant, 8) and S. pneumoniae (penicillin susceptible, ≤0.015; resistant, 1). Against ceftazidime-susceptible Enterobacteriaceae, the MIC90 of doripenem (0.12) was comparable to that of meropenem (0.12) and superior to that of imipenem (2), though susceptibility of isolates exceeded 99% for all evaluated carbapenems. The activity of doripenem was not notably altered against ceftazidime-nonsusceptible or extended-spectrum β-lactamase screen-positive Enterobacteriaceae. Doripenem was the most potent carbapenem tested against P. aeruginosa (MIC90/% susceptibility [%S]: ceftazidime susceptible = 2/92%S, nonsusceptible = 16/61%S; imipenem susceptible = 1/98.5%S, nonsusceptible = 8/56%S). Against imipenem-susceptible Acinetobacter spp., doripenem (MIC90 = 2, 89.1%S) was twice as active by MIC90 as were imipenem and meropenem. Overall, doripenem potency was comparable to those of meropenem and imipenem against gram-positive cocci and doripenem was equal or superior in activity to meropenem and imipenem against Enterobacteriaceae, including β-lactam-nonsusceptible isolates. Doripenem was the most active carbapenem tested against P. aeruginosa regardless of β-lactam resistance.

Oral Care as Prevention for Nonventilator Hospital-Acquired Pneumonia

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Karen K. Giuliano ◽  
Daleen Penoyer ◽  
Aurea Middleton ◽  
Dian Baker
Keyword(s):  
Oral Care ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

Factors predicting non-ventilated hospital-acquired pneumonia: Systematic review and Meta-analysis

2021 ◽  
Author(s):  
Stephani Amanda Lukasewicz Ferreira ◽  
Camila Hubner Dalmora ◽  
Franciele Anziliero ◽  
Ricardo de Souza Kuchenbecker ◽  
Patrícia Klarmann Ziegelmann
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

scholarly journals Animal models of hospital-acquired pneumonia: current practices and future perspectives

2017 ◽  
Vol 5 (6) ◽  
pp. 132-132 ◽  
Author(s):  
Kenny Bielen ◽  
Bart ’S Jongers ◽  
Surbhi Malhotra-Kumar ◽  
Philippe G. Jorens ◽  
Herman Goossens ◽  
...  
Keyword(s):  
Animal Models ◽  
Future Perspectives ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired ◽  
Current Practices

scholarly journals 58 * OVERDIAGNOSIS OF HOSPITAL ACQUIRED PNEUMONIA IN OLDER PEOPLE RATES AND REASONS FROM A PROSPECTIVE SURVEY

2015 ◽  
Vol 44 (suppl 1) ◽  
pp. i19-i19
Author(s):  
A. M. Clinton ◽  
R. J. G. Price ◽  
L. A. Burton ◽  
K. E. Barr ◽  
S. M. McAuley ◽  
...  
Keyword(s):  
Older People ◽  
Prospective Survey ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired
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