Voltage-gated potassium channels (Kv) in GtoPdb v.2021.3
Keyword(s):
The 6TM family of K channels comprises the voltage-gated KV subfamilies, the EAG subfamily (which includes hERG channels), the Ca2+-activated Slo subfamily (actually with 7TM, termed BK) and the Ca2+-activated SK subfamily. These channels possess a pore-forming α subunit that comprise tetramers of identical subunits (homomeric) or of different subunits (heteromeric). Heteromeric channels can only be formed within subfamilies (e.g. Kv1.1 with Kv1.2; Kv7.2 with Kv7.3). The pharmacology largely reflects the subunit composition of the functional channel.
Keyword(s):
2019 ◽
Vol 2019
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2003 ◽
Vol 52
(2)
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pp. 146-154
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1992 ◽
Vol 262
(3)
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pp. C678-C681
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1998 ◽
Vol 273
(5)
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pp. 2639-2644
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KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition
2011 ◽
Vol 101
(6)
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pp. 1364-1375
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2004 ◽
Vol 125
(1)
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pp. 71-80
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1998 ◽
Vol 13
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pp. 177-182
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