Artificial Neural Networks Improve the Accuracy of Clinical Data Prediction

Abstract Objective This study was aimed to investigate machine learning (ML) and artificial neural networks (ANNs) in the prognostic modeling of lung cancer, utilizing high-dimensional data. Materials and Methods A computed tomography (CT) dataset of inoperable nonsmall cell lung carcinoma (NSCLC) patients with embedded tumor segmentation and survival status, comprising 422 patients, was selected. Radiomic data extraction was performed on Computation Environment for Radiation Research (CERR). The survival probability was first determined based on clinical features only and then unsupervised ML methods. Supervised ANN modeling was performed by direct and hybrid modeling which were subsequently compared. Statistical significance was set at <0.05. Results Survival analyses based on clinical features alone were not significant, except for gender. ML clustering performed on unselected radiomic and clinical data demonstrated a significant difference in survival (two-step cluster, median overall survival [ mOS]: 30.3 vs. 17.2 m; p = 0.03; K-means cluster, mOS: 21.1 vs. 7.3 m; p < 0.001). Direct ANN modeling yielded a better overall model accuracy utilizing multilayer perceptron (MLP) than radial basis function (RBF; 79.2 vs. 61.4%, respectively). Hybrid modeling with MLP (after feature selection with ML) resulted in an overall model accuracy of 80%. There was no difference in model accuracy after direct and hybrid modeling (p = 0.164). Conclusion Our preliminary study supports the application of ANN in predicting outcomes based on radiomic and clinical data.

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Analysis of Artificial Neural Network Accuracy Using Backpropagation Algorithm In Predicting Process (Forecasting)

IJISTECH (International Journal Of Information System & Technology) ◽

10.30645/ijistech.v1i1.4 ◽

2017 ◽

Vol 1 (1) ◽

pp. 34 ◽

Cited By ~ 1

Author(s):

Sandy Putra Siregar ◽

Anjar Wanto

Keyword(s):

Neural Network ◽

Neural Networks ◽

Artificial Neural Network ◽

Artificial Neural Networks ◽

Backpropagation Algorithm ◽

Neural Structure ◽

Data Prediction ◽

Architectural Models ◽

Artificial Neural ◽

North Sumatra

Artificial Neural Networks are a computational paradigm formed based on the neural structure of intelligent organisms to gain better knowledge. Artificial neural networks are often used for various computing purposes. One of them is for prediction (forecasting) data. The type of artificial neural network that is often used for prediction is the artificial neural network backpropagation because the backpropagation algorithm is able to learn from previous data and recognize the data pattern. So from this pattern backpropagation able to analyze and predict what will happen in the future. In this study, the data to be predicted is Human Development Index data from 2011 to 2015. Data sourced from the Central Bureau of Statistics of North Sumatra. This research uses 5 architectural models: 3-8-1, 3-18-1, 3-28-1, 3-16-1 and 3-48-1. From the 5 models of this architecture, the best accuracy is obtained from the architectural model 3-48-1 with 100% accuracy rate, with the epoch of 5480 iterations and MSE 0.0006386600 with error level 0.001 to 0.05. Thus, backpropagation algorithm using 3-48-1 model is good enough when used for data prediction.

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