Idiopathic thrombocytopenic purpura in childhood: a population-based study in Qatar

2009 ◽  
Vol 0 (0) ◽  
Author(s):  
Naima Al-Mulla ◽  
Abdulbari Bener ◽  
Aliaa Amer ◽  
Mohammed Abu Laban
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Population Based ◽  
Population Based Study ◽  
Thrombocytopenic Purpura

The incidence of idiopathic thrombocytopenic purpura among adults: a population-based study and literature review

2009 ◽  
Vol 83 (2) ◽  
pp. 83-89 ◽  
Author(s):  
Page E. Abrahamson ◽  
Susan A. Hall ◽  
Maurille Feudjo-Tepie ◽  
Fanny S. Mitrani-Gold ◽  
John Logie
Keyword(s):  
Literature Review ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Population Based ◽  
Population Based Study ◽  
Thrombocytopenic Purpura

Risk of systemic lupus erythematosus in patients with idiopathic thrombocytopenic purpura: a population-based cohort study

2020 ◽  
pp. annrheumdis-2020-217013 ◽  
Author(s):  
Fang-Xiao Zhu ◽  
Jing-Yang Huang ◽  
Zhizhong Ye ◽  
Qing-Qing Wen ◽  
James Cheng-Chung Wei
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cohort Study ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Lupus Erythematosus ◽  
Cox Model ◽  
Population Based ◽  
Sensitivity Analyses ◽  
Systemic Lupus ◽  
Thrombocytopenic Purpura ◽  
Incident Cases

BackgroundIdiopathic thrombocytopenic purpura (ITP) may play a role in early-stage systemic lupus erythematosus (SLE). The incidence of SLE in patients with ITP and the potential relationship between them is still unclear. This study was performed to provide epidemiological evidence regarding the relationship between ITP and SLE occurrence.MethodsIn this population-based retrospective cohort study, the risk of SLE was analysed in a cohort of patients newly diagnosed with ITP between 2000 and 2013. Controls were selected at a 1:2 ratio through propensity score matching (PSM) using the greedy algorithm. The Cox proportional hazard model was used to analyse the association between ITP and SLE incidence. There were four different Cox regression models, and the sensitivity analyses were implemented to evaluate the HR of SLE after exposure with ITP.ResultsIn the age-matched and sex-matched ITP and non-ITP cohort, the average follow-up time was about 80 months in this study. There were 34 (4.70%) and 27 (0.19%) incident cases of SLE in ITP and non-ITP group. The incidence rates were 62.0 (95% CI 44.3 to 86.8) and 2.10 (95% CI 1.44 to 3.06), respectively. The adjusted HR of incidental SLE in the ITP group was 25.1 (95% CI 13.7 to 46.0). The other risk factors for SLE were female sex and Sjogren’s syndrome. After PSM, the incidence rate and Kaplan-Meir curves of SLE were consistent with the results for the age-matched and sex-matched population, the HR 17.4 (95% CI 5.28 to 57.4) was estimated by conditional Cox model.ConclusionThis cohort study demonstrated that patients with ITP have a higher risk of SLE. Clinically, patients with ITP should be monitored for incidental lupus.

Risk of fracture in Crohn's disease: A population-based study

2001 ◽  
Vol 120 (5) ◽  
pp. A628-A628
Author(s):  
E LOFTUSJR ◽  
C CROWSON ◽  
W SANDBORN ◽  
W TREAMINE ◽  
W OFALLON ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Population Based Study ◽  
Risk Of Fracture
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