Assessing the Circadian Potential of an Office Building in the Southeastern US

Visual Comfort Assessment of Different Shading Strategies in a Commercial Office Building in the Southeastern US

10.14305/ibpc.2018.hf-4.06 ◽

2018 ◽

Author(s):

Armin Amirazar ◽

Mona Azarbayjani ◽

Ben Futrell ◽

Amir Hosseinzadeh Zarrabi ◽

Roshanak Ashrafi

Keyword(s):

Office Building ◽

Visual Comfort ◽

Southeastern Us

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Hepatocyte Alterations in Guinea Pigs FED Polychlorinated Biphenyls (PCBs), Dibenzodioxins (PCDD), AND DIBENZOFURANS (PCDF)

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100053085 ◽

1982 ◽

Vol 40 ◽

pp. 56-57

Author(s):

J. N. Turner ◽

D. N. Collins

Keyword(s):

Guinea Pigs ◽

Room Temperature ◽

Dose Group ◽

Methyl Cellulose ◽

Uranyl Acetate ◽

Target Organ ◽

Office Building ◽

Lead Citrate ◽

Control Groups ◽

Cooling Fluid

A fire involving an electric service transformer and its cooling fluid, a mixture of PCBs and chlorinated benzenes, contaminated an office building with a fine soot. Chemical analysis showed PCDDs and PCDFs including the highly toxic tetra isomers. Guinea pigs were chosen as an experimental animal to test the soot's toxicity because of their sensitivity to these compounds, and the liver was examined because it is a target organ. The soot was suspended in 0.75% methyl cellulose and administered in a single dose by gavage at levels of 1,10,100, and 500mgm soot/kgm body weight. Each dose group was composed of 6 males and 6 females. Control groups included 12 (6 male, 6 female) animals fed activated carbon in methyl cellulose, 6 males fed methyl cellulose, and 16 males and 10 females untreated. The guinea pigs were sacrificed at 42 days by suffocation in CO2. Liver samples were immediately immersed and minced in 2% gluteraldehyde in cacadylate buffer at pH 7.4 and 4°C. After overnight fixation, samples were postfixed in 1% OsO4 in cacodylate for 1 hr at room temperature, embedded in epon, sectioned and stained with uranyl acetate and lead citrate.

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