MODIFIED ENDOVENTRICULAR CIRCULAR PLASTY (DOR PROCEDURE) IN A PATIENT PRESENTING WITH ACUTE SHORT-TERM MEMORY LOSS

1. Memory in day-old-chickens during the first few hours after learning can be made to decline by the prior intracranial injection of two classes of drugs. 2. Sodium pump inhibitors in increasing doses cause increasingly rapid loss of memory. 3. Protein synthesis inhibitors in increasing doses attain a maximum potency in causing memory decline and the rate may not be further accelerated by higher doses. 4. Adding a sodium pump inhibitor to the inhibition of protein synthesis increases memory loss. 5. Adding a protein synthesis inhibitor to a sodium pump inhibitor causes no further loss. 6. Therefore within a few minutes of learning a short-term memory of limited time span but independent of protein synthesis becomes supplemented and eventually replaced by a long-term storage requiring protein synthesis. The amount of long-term store is set by the amount of short-term memory. 7. The short-term store could be directly dependent on post-activation enhancement of Na + extrusion from neurons. Some physiological mechanisms by which this could be achieved and how this might activate protein synthesis are discussed.

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P106: Fronto-parietal coherence in the assessment of short-term memory loss in patients with partial epilepsy

Clinical Neurophysiology ◽

10.1016/s1388-2457(14)50256-8 ◽

2014 ◽

Vol 125 ◽

pp. S76-S77

Author(s):

A. Kostylev ◽

A. Ivanov

Keyword(s):

Short Term Memory ◽

Memory Loss ◽

Partial Epilepsy ◽

Short Term ◽

Term Memory

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Tocainide: A Severe Adverse Reaction

Drug Intelligence & Clinical Pharmacy ◽

10.1177/106002808802200209 ◽

1988 ◽

Vol 22 (2) ◽

pp. 142-145 ◽

Cited By ~ 3

Author(s):

James M. Dunn ◽

Paul E. Groth ◽

Anne DeSimone

Keyword(s):

Adverse Reaction ◽

Short Term Memory ◽

Memory Loss ◽

Uneventful Recovery ◽

Physical Status ◽

Short Term ◽

Severe Adverse Reaction ◽

Premature Ventricular Contractions ◽

Term Memory ◽

Cardioactive Drug

Tocainide is a primary analog of lidocaine with antiarrhythmic properties used to treat ventricular rhythm disorders. A 76-year-old man with benign paroxysmal premature ventricular contractions was treated with tocainide and developed a generalized maculopapular lupoid eruption, bleeding from the lips and gingivae, vertigo, gross tremors of the extremities, fever, and short-term memory loss, which required hospitalization. The patient recovered slowly over three months with no permanent sequelae after discontinuing the drug and receiving rigorous supportive care. His excellent physical status and absence of concomitant illness contributed to an uneventful recovery. Tocainide is a potent cardioactive drug with a long biological half-life and should be used with caution.

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LGI1 antibody encephalitis and psychosis

Australasian Psychiatry ◽

10.1177/1039856218771513 ◽

2018 ◽

Vol 26 (6) ◽

pp. 612-614 ◽

Cited By ~ 3

Author(s):

Dahai Wang ◽

Qinjian Hao ◽

Lan He ◽

Qiang Wang

Keyword(s):

Magnetic Resonance Imaging ◽

Short Term Memory ◽

Background Activity ◽

Early Recognition ◽

Memory Loss ◽

Psychotic Symptoms ◽

Resonance Imaging ◽

Short Term ◽

Term Memory ◽

Hippocampal Lesions

Objective: To describe a case of leucine-rich, glioma inactivated 1 antibody-encephalitis presenting with psychosis. Methods: Case report. Results: A young man with leucine-rich, glioma inactivated 1-antibody encephalitis initially presented with acute psychotic symptoms, short-term memory loss and faciobrachial dystonic seizures. Magnetic resonance imaging revealed hippocampal lesions. Electroencephalography revealed frontotemporal slowing of background activity. Conclusion: Increased awareness of leucine-rich, glioma inactivated 1-antibody encephalitis may promote early recognition and treatment.

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