REMISSION OF A CASE OF MULTIPLE HYMENOPTERA STINGS-ASSOCIATED CHRONIC URTICARIA DURING VENOM IMMUNOTHERPY

Mapping Intimacies ◽

10.22541/au.161117170.07846154/v1 ◽

2021 ◽

Author(s):

Marco Dubini ◽

Valerio Pravettoni ◽

Federica Rivolta ◽

Giulia Segatto ◽

Riccardo Asero ◽

...

Keyword(s):

Chronic Urticaria ◽

Venom Immunotherapy ◽

Acute Urticaria ◽

Hymenoptera Sting ◽

Wasp Stings

The role of Immunotherapy in Chronic Urticaria is unclear, except for isolated circumstances. Hymenoptera sting causes acute urticaria and no report of CU after Hymenoptera sting can be found in the literature. We describe a case of onset of CU after multiple wasp stings that remitted during venom immunotherapy.

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The role of transcription factor FoxP3 as a predictor of acute and chronic urticaria in children

Medical Herald of the South of Russia ◽

10.21886/2219-8075-2021-12-3-50-54 ◽

2021 ◽

Vol 12 (3) ◽

pp. 50-54

Author(s):

S. V. Maltsev ◽

L. P. Sizyakina ◽

A. A. Lebedenko

Keyword(s):

Transcription Factor ◽

Chronic Urticaria ◽

Chronic Spontaneous Urticaria ◽

Immunological Methods ◽

Control Group ◽

Acute Urticaria ◽

Clinical Methods ◽

Regulatory Lymphocytes

Objective: To study the transcription factor FoxP3 in children with acute and chronic spontaneous urticaria as a possible predictor of the severity and chronicity of urticaria.Materials and Methods: A total of 264 children of both sexes aged from 6 to 16 years old with diff erent variants of urticaria course were examined. Clinical methods of the study included the analysis of anamnestic data and an objective examination of the child with the determination of the severity of urticaria. Immunological methods of the study included the identifi cation of T-regulatory lymphocytes with the CD4+CD25+ Foxp3+CD45+immunophenotype.Results: A signifi cant decrease in the level of transcription factor FoxP3 was found in children with severe acute urticaria and chronic urticaria compared to the control group.Conclusion: Th e degree of reduction in the level of FoxP3 signifi cantly aff ected the likelihood of the development of a severe course of acute urticaria and possible chronization of the disease.

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Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria

Mediators of Inflammation ◽

10.1155/s0962935196000191 ◽

1996 ◽

Vol 5 (2) ◽

pp. 113-115 ◽

Cited By ~ 12

Author(s):

G. Di Lorenzo ◽

P. Mansueto ◽

M. Melluso ◽

G. Candore ◽

D. Cigna ◽

...

Keyword(s):

Chronic Urticaria ◽

Eosinophil Cationic Protein ◽

Chronic Idiopathic Urticaria ◽

Blood Eosinophil ◽

Cationic Protein ◽

Acute Urticaria ◽

Asymptomatic Patients ◽

The Moment ◽

Blood Eosinophils ◽

Eosinophil Counts

We have analysed the relationship of blood eosinophil count and serum eosinophil cationic protein (ECP) levels in patients with acute and chronic idiopathic urticaria. The ECP levels and eosinophil counts were measured in the peripheral blood of 15 patients with acute urticaria, 25 with chronic idiopathic urticaria and 10 normal healthy subjects. Blood eosinophil counts and serum ECP levels increased in all patients with acute urticaria. Concerning patients affected by chronic urticaria, taking into account the recrudescence of the disease at the moment of taking the blood sample, only symptomatic patients showed increased eosinophil blood values whereas serum ECP levels were increased both in symptomatic and asymptomatic patients. Furthermore, serum ECP levels in chronic urticaria did not correlate with the peripheral eosinophil counts, as they did in acute urticaria. The results of the present study indicate that eosinophils may play a role in the inflammatory mechanisms in patients with acute and chronic urticaria showing a positive correlation between serum ECP levels and disease activity.

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The Role of Platelets in Chronic Urticaria

International Archives of Allergy and Immunology ◽

10.1159/000444085 ◽

2016 ◽

Vol 169 (2) ◽

pp. 71-79 ◽

Cited By ~ 8

Author(s):

Gino Antonio Vena ◽

Nicoletta Cassano ◽

Angelo Valerio Marzano ◽

Riccardo Asero

Keyword(s):

Chronic Urticaria

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Specific IgG and IgG4 in patients with IgE-antibodies against Anisakis simplex: Acute urticaria in gastro-allergic anisakiasis versus chronic urticaria

Journal of Allergy and Clinical Immunology ◽

10.1016/s0091-6749(02)81498-1 ◽

2002 ◽

Vol 109 (1) ◽

pp. S126-S126 ◽

Cited By ~ 2

Author(s):

Alvaro Daschner ◽

Francisco Vega de La Osada ◽

Begoña González Leza

Keyword(s):

Chronic Urticaria ◽

Anisakis Simplex ◽

Ige Antibodies ◽

Acute Urticaria ◽

Specific Igg

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Diagnostic features of chronic urticaria

Russian Journal of Skin and Venereal Diseases ◽

10.18821/1560-9588-2016-19-5-290-295 ◽

2016 ◽

Vol 19 (5) ◽

pp. 290-295

Author(s):

N. G Kochergin ◽

P. V Kolkhir ◽

Olga A. Kosoukhova

Keyword(s):

Chronic Urticaria ◽

Eosinophil Cationic Protein ◽

Autologous Serum ◽

Diagnostic Features ◽

Cationic Protein ◽

Complement Components ◽

Autologous Serum Skin Test ◽

Acute Urticaria ◽

Physical Urticaria ◽

Working Age

Urticaria is etiologically heterogeneous disease, where the main clinical sign is a wheal. For the duration of the disease course secrete acute and chronic urticaria. If urticaria elements in the skin of the patient are observedfrom several hours to 6 weeks, it is classified as acute urticaria, cutaneous if the process continues for more than 6 weeks, it is a chronic urticaria. The aim of our work was the optimization of diagnosis of chronic urticaria on the basis of the study of clinical and allergological and immunological characteristics of the testing results. The study involved 60 patients between the ages of 18 to 73 years with confirmed clinical diagnosis of chronic urticaria. The study was conducted in the clinic of skin and venereal diseases ofI.M. Sechenov First Medical State Medical University. Conducted clinical and anamnestic examination: medical history, assessment of complaints, determining the severity of urticaria (UAS7), quality of life (CU-Q2oL, DLQI), control of the symptoms of urticaria (UCT); laboratory tests: clinical blood test, C-reactive protein, thyroid hormones and antibodies to thyroid structures, tests to exclude physical urticaria, autologous serum skin test, D-dimer, rheumatoid factor, eosinophil-cationic protein, the total of IgE, antinuclear antibodies , C3 / C4 complement components, protein fractions, coagulation, urinalysis, general analysis offeces, feces on eggs of worms and protozoa. The study was conducted within 1 month and included diagnostic consultation period and 5 consultations every 7 days. Identified specific clinical and laboratory features that can be assigned to the diagnostic criteria for autoimmune form of chronic urticaria, which will continue to pick up these patients rational treatment. The high prevalence of urticaria, a variety offorms of the disease, the presence ofpathology predominantly in patients of working age, often ineffective diagnostic actions cause the urgency of the problem and the need for further study of this disease.

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