scholarly journals A randomized double-blind comparison of kinesio and athletic taping in the treatment of lateral epicondylitis: Clinical and sonographic outcomes

2021 ◽  
Author(s):  
Sezen Savran ◽  
Ugur Toprak ◽  
Gul Baltaci ◽  
Nilgun Bek
Keyword(s):  
Healing Process ◽  
Substantial Reduction ◽  
Lateral Epicondylitis ◽  
Pinch Strength ◽  
Dash Score ◽  
Clinical Tests ◽  
Short Term Treatment ◽  
Double Blind ◽  
Physiotherapy Program ◽  
Tendon Thickness

Objective: To compare early effects of the application of kinesio and athletic taping as part of the intensive conservative physiotherapy of the lateral epicondylitis using the results from ultrasonography and clinical tests. Methods: Twenty-eight volunteers aged from 27 to 55 years old who had been clinically diagnosed with the lateral epicondylitis received in addition to the 4-week conventional physiotherapy program, one group was treated with athletic taping (n=14), the other with kinesio taping (n=14). The patients were evaluated through clinical tests (visual analog scoring, isokinetic elbow, grip and pinch strength tests, a Disability of Arm and Shoulder questionnaire (DASH) and ultrasonography examination on the first and last days of the physiotherapy program. Results: The two groups had similar characteristics in all the baseline findings-and they showed improvement in the DASH score and the regression in pain scores. The activity pain was further reduced in the kinesio group (p = 0.006). However, there were no significant differences in isokinetic muscle strength at 600 /s and 1200 /s velocity speeds between kinesio and athletic groups. There was also a substantial reduction in the tendon thickness in the kinesio group (p = 0.063, 0.031, 0.07; respectively) The tendon thickness was reduced by 92.3% in the kinesio-taped patients, and only 22.2% in the athletic taped patients. The presence of a tear in the tendon had a negative effect on the tendon thickness reduction (p < 0.001). Conclusions: The results showed that physiotherapy coupled with the kinesiotaping was considered to be the better choice in the short-term treatment of the lateral epicondylitis. Since the presence of a tear has an impact on the healing process, ultrasonography might be an efficient method to use to discover the existence of a tear in the tendon and informing the decision about the appropriate type of treatment.

A new surgical technique for the treatment of scaphotrapezial arthritis associated with trapeziometacarpal arthritis: the narrow pseudoarthrosis

2016 ◽  
Vol 41 (7) ◽  
pp. 710-718 ◽  
Author(s):  
M. Rubino ◽  
L. Cavagnaro ◽  
V. Sansone
Keyword(s):  
Simple Technique ◽  
Stage Iv ◽  
Pinch Strength ◽  
Dash Score ◽  
Level Of Evidence ◽  
First Ray ◽  
Excision Arthroplasty ◽  
Surgical Treatments ◽  
New Surgical Technique

We describe a technique for treating Eaton stage IV osteoarthritis of the first ray, which is a development of our previously published technique for treating trapeziometacarpal arthritis. This simple technique is based on a limited resection arthroplasty of the first trapeziometacarpal and the scaphotrapezial joints, with the aim of inducing the formation of a narrow pseudoarthrosis at both sites. A total of 26 consecutive patients were treated for Eaton stage IV arthritis at a mean follow-up of 4.7 years (range 3.2–6.6). There were statistically significant improvements in all clinical parameters: mean appositional and oppositional pinch strength, mean DASH score (65 points pre-operatively to 8.7 points at final follow-up), and in mean visual analogue scale score (8.6 to 0.2 points). Although a larger cohort and a longer follow-up will be necessary to evaluate this new technique fully, these results encourage us to believe that the limited excision arthroplasty of the trapeziometacarpal and scaphotrapezial joints is a viable alternative to the existing surgical treatments for stage IV thumb arthritis. Level of evidence: 4

DOUBLE-BLIND COMPARISON OF IBUPROFEN AND PHENYLBUTAZONE IN THE SHORT-TERM TREATMENT OF RHEUMATOID ARTHRITIS

Rheumatology ◽  
1973 ◽  
Vol 12 (2) ◽  
pp. 68-73 ◽  
Author(s):  
K. PAVELKA ◽  
A. SUSTA ◽  
O. VOJTÍŠEK ◽  
A. BREMOVÁ ◽  
D. KAŇKOVÁ ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Term Treatment ◽  
Short Term ◽  
Short Term Treatment ◽  
Double Blind ◽  
Blind Comparison

Bioabsorbable dressing impregnated with betamethasone and ciprofloxacin after endoscopic sinus surgery: A randomized, double-blind, placebo-controlled study

2021 ◽  
pp. 014556132110624
Author(s):  
Małgorzata Wierzchowska ◽  
Paulina Kalińczak-Górna ◽  
Błażej Grześkowiak ◽  
Kamil Radajewski ◽  
Jakub Burduk ◽  
...  
Keyword(s):  
Endoscopic Sinus Surgery ◽  
Healing Process ◽  
Nasal Packing ◽  
Sinus Surgery ◽  
Controlled Study ◽  
Nasal Surgery ◽  
Double Blind ◽  
Nasal Blockage ◽  
Positive Effects ◽  
Mucosal Edema

Background In addition to its hemostatic and stabilization role, biodegradable nasal packing can be used as a carrier for drugs after functional endoscopic sinus surgery (FESS). The aim of this study was to compare the influence of biodegradable synthetic polyurethane foam (NasoPore) soaked with ciprofloxacin, or betamethasone, or both to the same foam soaked with saline after FESS. Methods 120 adults with chronic rhinosinusitis, with and without polyps, directed for bilateral full-house FESS were enrolled for the study. The patients were randomized and blinded into 3 groups, depending on the type of postoperative procedure applied. Thus, NasoPore soaked with antibiotic was provided to the first group; in the second group, the steroid was used; and the combination of both, in the third group. In each case, the aforementioned procedure was administered on one side of the nose, while NasoPore was soaked in saline on the other, at the end of the surgery, respectively. The patients were requested to complete a questionnaire during their postoperative visits at 2, 10, 30, 90, and 180 days, scoring the level of complaints on the VAS scale, separately for each side. The evaluation of the healing process was performed at each visit using rigid endoscopy and subsequently rated on numerical scales. Results Decreased mucosal edema and secretion; reduced Lund-Kennedy score; and favorable influences on facial pressure, nasal blockage, and smell were most evidently seen in the group receiving the antibioticsteroid combination. Conclusions The application of biodegradable nasal packing with betamethasone and ciprofloxacin in sino-nasal surgery has positive effects not only on the healing process but also impacts patient’s comfort. To optimize it, however, further research is needed.

Abstract 8: A Phase IIb Double-blind, Randomized, Placebo Controlled Study of GSK249320 for Stroke Recovery

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Steven C Cramer ◽  
Lori A Enney ◽  
Colleen K Russell ◽  
Monica Simeoni ◽  
Thomas R Thompson
Keyword(s):  
Monoclonal Antibody ◽  
Substantial Reduction ◽  
Indirect Evidence ◽  
Primary Outcome Measure ◽  
Clinical Findings ◽  
Stroke Recovery ◽  
Gait Velocity ◽  
Controlled Study ◽  
Double Blind ◽  
Target Binding

Introduction: One class of potential post-stroke restorative therapy focuses on promoting axon outgrowth by blocking myelin-based inhibitory proteins such as myelin-associated glycoprotein (MAG). The aim of the current study was to extend preclinical and clinical findings of GSK249320, an IgG1-type monoclonal antibody to MAG, to explore effects on motor outcomes after stroke. Methods: This was a phase IIb double-blind, randomized, placebo controlled study (GSK funded; clinicaltrials.gov # NCT01808261). At 30 international sites, patients with ischemic stroke 24-72 hours prior and deficits in gait were randomized to two IV infusions of GSK249320 or placebo. Primary outcome measure was change in gait velocity from baseline to Day 90. Results: A total of 134 subjects were randomized. The two groups were overall well matched at baseline. The study was stopped at the pre-specified interim analysis because the treatment difference met the predefined futility criteria cutoff. Secondary endpoints, including gait analyzed categorically and upper extremity function (Box & Blocks score), were concordant. The two IV infusions of GSK249320 were well tolerated. Although direct evidence that the therapy reached the biological target was not available, indirect evidence of target binding was suggested by the substantial reduction in free MAG plasma levels with GSK249320 treatment. Conclusions: The monoclonal antibody GSK249320 administered IV within 72 hours of stroke onset demonstrated no improvement in gait velocity as compared to placebo. The antibody was well tolerated and showed low immunogenicity, findings that may prove useful to future studies aiming to use a monoclonal antibody to modify activity in specific biological pathways in order to improve recovery from stroke.

A Multicenter, Randomized, Double-Blind Study Comparing a Daily Bedtime Administration of Famotidine and Ranitidine in Short-Term Treatment of Active Duodenal Ulcer

Digestion ◽  
1989 ◽  
Vol 42 (2) ◽  
pp. 79-85 ◽  
Author(s):  
R. Alcalá-Santaella ◽  
J. Guardia ◽  
J. Pajares ◽  
J. Piqué ◽  
L. Pita ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Term Treatment ◽  
Blind Study ◽  
Double Blind Study ◽  
Short Term ◽  
Short Term Treatment ◽  
Double Blind

Description and Clinical Assessment of the Bone Block Tendon Interposition Technique for the Management of Thumb Carpometacarpal Joint Osteoarthritis

2018 ◽  
Vol 23 (04) ◽  
pp. 515-519
Author(s):  
Diego F. Rincon Cardozo ◽  
Wynston J. Alvarez Martinez ◽  
Jhon F. Castañeda Lopez ◽  
Fredy A. Angarita Maldonado ◽  
Juliana A. Rojas Neira ◽  
...  
Keyword(s):  
Case Series ◽  
Functional Results ◽  
Interference Screw ◽  
Pinch Strength ◽  
Bone Block ◽  
Dash Score ◽  
Carpometacarpal Joint ◽  
Thumb Carpometacarpal Joint ◽  
Thumb Carpometacarpal ◽  
And Function

Background: Pellegrini’s surgical technique is the most useful for thumb carpometacarpal joint osteoarthritis. The purpose of this paper is to describe the technique of a modified version using a bone block in the tunnel through which the flexor carpi radialis tendon is passed (BBTI). Methods: Case series of patients diagnosed with osteoarthritis of the thumb carpometacarpal joint, in stage II or higher based on Eaton’s classification, that were intervened using the BBTI technique for a 2-year period. Grip and pinch strength, range of motion, and 1–2 metacarpal angle were evaluated. Pain and function were measured using the visual analogue scale and the Disabilities of the Arm, Shoulder and Hand (DASH) scale. Results: The study included 16 cases in 14 patients (11 women and 3 men), with an average age of 55.7 ± 7.1 years. Encouraging results were obtained, with an average DASH score of 24.3 ± 17.9 and a minimum VAS pain score. A total of 58% showed a grip strength of over 80% and the postoperative movement was equivalent to the contralateral limb. No cases of infection were reported, and only two minor complications were observed. Conclusions: The BBTI technique is a surgical option that incorporates an interference screw, offering good functional results for managing osteoarthritis of the thumb carpometacarpal joint, with a similar complication rate to that of the original technique.

scholarly journals Effects of Kinesio-Taping in Lateral Epicondylitis: A Narrative Review

2021 ◽  
pp. 219-225
Author(s):  
Aloysius Rodrigues ◽  
Saumya Srivastava
Keyword(s):  
Musculoskeletal Disorder ◽  
Healing Process ◽  
Lateral Epicondylitis ◽  
The Body ◽  
Narrative Review ◽  
Medical Databases ◽  
Kinesio Taping ◽  
Current Review ◽  
Comprehensive Search ◽  
Taping Technique

Aim: The objective of this narrative review was to assess the effects of Kinesio-Taping in Lateral Epicondylitis. Methods: A comprehensive search of already published relevant articles only from medical databases like Google Scholar, PubMed and ScienceDirect was carried out for obtaining the same from the year 2014-2019. Background: Lateral epicondylitis is a familiar musculoskeletal disorder that primarily affects the extensors of the wrist. Kinesio-taping (KT) is a newer generation taping technique that aid's the body’s healing process whilst supporting and giving stability to the muscles and joints without hindering the range of motion of the body. Conclusion: The current review recognises the need for Kinesio-Taping in individuals with Lateral Epicondylitis as it has shown to enhance the functionality of the wrists and reduce pain. Limitations:  More in-depth studies are to be conducted to find out the mechanism behind Kinesio-Taping.

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