A rare case of Creutzfeldt-Jakob disease presenting with amyotrophic lateral sclerosis

Here, we present 76-year-old woman, who presented with a history of quadriparesis from three years ago, initially in the lower extremities and ascended towards the upper extremities (symmetrical and progressive). Magnetic resonance imaging revealed bilateral thalamic lesions (Figure 1), which could identify it as a variant of Creutzfeldt-Jakob disease.