scholarly journals Amnioreduction in treatment of increased amniotic fluid volume

2004 ◽  
Vol 57 (11-12) ◽  
pp. 579-583 ◽  
Author(s):  
Sinisa Stojic ◽  
Aleksandra Novakov-Mikic ◽  
Mirjana Bogavac ◽  
Aljosa Mandic
Keyword(s):  
Amniotic Fluid ◽  
Placental Abruption ◽  
Fetal Lung ◽  
Symptomatic Treatment ◽  
Fluid Volume ◽  
Premature Delivery ◽  
Lung Maturation ◽  
Monochorionic Twins ◽  
Amniotic Fluid Volume ◽  
Fetal Lung Maturation

Introduction Increased amniotic fluid volume may significantly increase the risk for preterm delivery. Amniodrainage is a symptomatic treatment by which excess amniotic fluid is reduced to provide fetal lung maturation. The aim of this study is to estimate the efficacy and safety of this procedure, our results and give a literature review. Material and methods Sonografic criteria were used (AFI> 400 ml, or the biggest amniotic fluid pocket > 150 mm) to choose patients in whom 18G needle was used to allow leaking of excessive amniotic fluid. Results 10 patients underwent 26 procedures. The procedures were performed at 28.6th week gestation, on average and 6.25 weeks average gain or 1000 g. We had two sets of monochorionic twins with twin-to-twin transfusion syndrome (TTTS), where one child survived. One procedure was followed by premature placental abruption, and premature delivery in 28th week. The rest of procedures were uneventful. Conclusion In our series of 10 women, 26 procedures were performed to prolong pregnancies, enable fetal maturation and weight gain. In majority of cases amnioreduction was done without complications, so we could repeat the intervention and prolong the pregnancy. Survival of one child in two TTTS pregnancies should not be regarded unsuccessful in our conditions.

SARS-CoV-2: do corticosteroids for fetal lung maturation worsen maternal or fetal outcomes?

2021 ◽  
Vol 29 (2) ◽  
pp. 90-92
Author(s):  
Nashwa Eltaweel ◽  
Samuel Lockley ◽  
Irshad Ahmed ◽  
Bee K Tan
Keyword(s):  
Case Studies ◽  
Clinical Case ◽  
Intraventricular Haemorrhage ◽  
Fetal Lung ◽  
Premature Delivery ◽  
Lung Maturation ◽  
Antenatal Steroids ◽  
Clinical Case Studies ◽  
Inflammatory Processes ◽  
Fetal Lung Maturation

Immune system changes during pregnancy could make pregnant women more susceptible to SARS-Cov-2 infection. The use of corticosteroids within obstetrics has been shown to reduce the risks of respiratory distress syndrome, intraventricular haemorrhage, necrotizing enterocolitis and neonatal death in the baby associated with premature delivery. During the COVID-19 pandemic, corticosteroids have been trialled as a treatment to dampen the ‘cytokine storm’ and associated inflammatory processes. Corticosteroids have long been known to have immunosuppressive effects that could hinder the body's ability to mount a defence against COVID-19 and thereby delaying viral clearance. In this clinical case studies, antenatal steroids for fetal lung maturation appear to be of benefit and did not result in a deterioration of maternal disease. Our clinical case studies support the current recommendations from the Royal College of Obstetricians and Gynaecologists ie corticosteroids for fetal lung maturation is appropriate in patients who are suspected or have confirmed SARS-CoV-2 infection.

Fetal lung maturation: Amniotic fluid catecholamines, phospholipids, and cortisol

1982 ◽  
Vol 142 (4) ◽  
pp. 440-444 ◽  
Author(s):  
Walter A. Divers ◽  
Ari Babaknia ◽  
Bill R. Hopper ◽  
Mahlon M. Wilkes ◽  
Samuel S.C. Yen
Keyword(s):  
Amniotic Fluid ◽  
Fetal Lung ◽  
Lung Maturation ◽  
Fetal Lung Maturation

scholarly journals AMNIOTIC FLUID CLARA CELL PROTEIN CONCENTRATION IN NORMAL PREGNANCY, A MARKER OF FETAL AIRWAY GROWTH OR FETAL LUNG MATURATION? † 1355

1996 ◽  
Vol 39 ◽  
pp. 228-228
Author(s):  
Andres Maturana ◽  
Alfred Bernard ◽  
Margarida Freund ◽  
Alfredo Germain ◽  
Vickey Thomas ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Protein Concentration ◽  
Fetal Lung ◽  
Normal Pregnancy ◽  
Clara Cell ◽  
Cell Protein ◽  
Lung Maturation ◽  
Clara Cell Protein ◽  
Fetal Lung Maturation

Amniotic Fluid Microviscosity Determined by Fluorescence Polarization: Methodology and Relation to Gestational Age

PEDIATRICS ◽  
1979 ◽  
Vol 63 (2) ◽  
pp. 213-218
Author(s):  
Raymond I. Stark ◽  
Thomas A. Blumenfeld ◽  
John D. George ◽  
Vincent J. Freda ◽  
L. Stanley James
Keyword(s):  
Amniotic Fluid ◽  
Fluorescence Polarization ◽  
Fetal Lung ◽  
Biochemical Properties ◽  
Degree Of Saturation ◽  
Lung Maturation ◽  
Bilirubin Concentration ◽  
Surfactant System ◽  
Lipid Aggregates ◽  
Fetal Lung Maturation

The fluorescence polarization of 116 amniotic fluid specimens obtained from 22 isoimmunized pregnant women was determined. The degree of fluorescence polarization of amniotic fluid provides an index of microvisocity in lipid aggregates that is dependent on the lecithin-to-sphingomyelin ratio and the degree of saturation of fatty acid side chains. We confirmed the reproducibility of the measurement of amniotic fluid microviscosity (coefficient of variation, 2.0%). The measurements are not effected by bilirubin concentration or amniotic fluid dilution. The pattern of change of amniotic fluid microviscosity during gestation parallels the expected development of the surfactant system. Amniotic fluid microviscosity is high during early gestation and abruptly and sequentially decreases between the 28th and 36th week of gestation. Since the measurements are an accurate reflection of the biochemical properties of amniotic fluid lipids and parallel the development of the surfactant system, we conclude that amniotic fluid microviscosity may well serve as an indicator of the process of fetal lung maturation.

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