scholarly journals Primary fallopian tube carcinoma

2009 ◽  
Vol 62 (1-2) ◽  
pp. 31-36 ◽  
Author(s):  
Ljiljana Mladenovic-Segedi
Keyword(s):  
Ovarian Carcinoma ◽  
Fallopian Tube ◽  
Female Genital Tract ◽  
Total Abdominal Hysterectomy ◽  
Cystic Mass ◽  
Common Finding ◽  
Ca 125 ◽  
Fallopian Tube Carcinoma ◽  
Brca1 And Brca2 ◽  
Primary Fallopian Tube Carcinoma

Introduction. Primary fallopian tube carcinoma is extremely rare, making 0.3-1.6% of all female genital tract malignancies. Although the etymology of this tumor is unknown, it is suggested to be associated with chronic tubal inflammation, infertility, tuberculous salpingitis and tubal endometriosis. High parity is considered to be protective. Cytogenetic studies show the disease to be associated with over expression of p53, HER2/neu and c-myb. There is also some evidence that BRCA1 and BRCA2 mutations have a role in umorogeneis. Clinical features. The most prevailing symptoms with fallopian tube carcinoma are abdominal pain, abnormal vaginal discharge/bleeding and the most common finding is an adnexal mass. In many patients, fallopian tube carcinoma is asymptomatic. Diagnosis. Due to its rarity, preoperative diagnosis of primary fallopian tube carcinoma is rarely made. It is usually misdiagnosed as ovarian carcinoma, tuboovarian abscess or ectopic pregnancy. Sonographic features of the tumor are non-specific and include the presence of a fluid-filled adnexal structure with a significant solid component, a sausage-shaped mass, a cystic mass with papillary projections within, a cystic mass with cog wheel appearance and an ovoid-shaped structure containing an incomplete separation and a highly vascular solid nodule. More than 80% of patients have elevated pretreatment serum CA-125 levels, which is useful in follow-up after the definite treatment. Treatment. The treatment approach is similar to that of ovarian carcinoma, and includes total abdominal hysterectomy and bilateral salpingo-oophorectomy. Staging is followed with chemotherapy.

scholarly journals Primary Fallopian Tube Carcinoma (PFTC), A Rare Malignancy of Female Genital Tract

2019 ◽  
Vol 38 (1) ◽  
pp. 49-52
Author(s):  
Farhana Binte Rashid ◽  
Mohammad Abul Kalam Azad
Keyword(s):  
Fallopian Tube ◽  
Genital Tract ◽  
Frozen Section ◽  
Correct Diagnosis ◽  
Female Genital Tract ◽  
Total Abdominal Hysterectomy ◽  
Ultrasound Finding ◽  
Fallopian Tube Carcinoma ◽  
Primary Fallopian Tube Carcinoma ◽  
Female Genital

Background: Primary fallopian tube carcinoma (PFTC) is one of the rarest malignancies of female genital tract. It represents <1% of all gynecologic malignancies. Preoperative diagnosis is uncommon due to its rarity and non-specific symptoms. In most cases diagnosis is made during surgery or histological examination. Rarity of this type of carcinoma prompted us to report it as individual case. Case: A 40-yearold parous women presented with bilateral PFTC. The patient gave a history of lower abdominal and pelvic pain for 2 years on several occasions. An abdominal ultrasound finding showed an adnexal mass and her CA125 level was 30IU/ml (normal- <35IU/ml). Clinically she was suspected as a case of pelvic inflammatory disease (PID). She underwent Total Abdominal Hysterectomy with bilateral salpingoophorectomy. Intraoperative findings were consistent with PID. Final pathologic analysis showed bilateral primary fallopian tube carcinoma —well differentiated serous adenocarcinoma. Post operatively she was referred for oncological management. Conclusion: Malignancy should be considered in the differential diagnosis of PID especially in premenopausal age and intraoperative frozen section biopsy is crucial to make correct diagnosis and to allow appropriate surgical staging. J Bangladesh Coll Phys Surg 2020; 38(1): 49-52

scholarly journals Primary Fallopian Tube Carcinoma: A Case Report and Literature Review

2017 ◽  
Vol 5 (3) ◽  
pp. 344-348 ◽  
Author(s):  
Meral Rexhepi ◽  
Elizabeta Trajkovska ◽  
Hysni Ismaili ◽  
Florin Besimi ◽  
Nagip Rufati
Keyword(s):  
Fallopian Tube ◽  
Female Genital Tract ◽  
Lower Abdominal Pain ◽  
Ca 125 ◽  
Histopathological Diagnosis ◽  
Fallopian Tube Carcinoma ◽  
Rare Tumour ◽  
Initial Surgery ◽  
Primary Fallopian Tube Carcinoma ◽  
The Right

BACKGROUND: Primary fallopian tube carcinoma (PFTC) is a rare tumour of the female genital tract with an incidence of 0.1-1.8% of all genital malignancies, and it is very difficult to diagnose preoperatively, because of its non-specific symptomatology. In most cases, it is an intraoperative finding or a histopathological diagnosis. It is a tumour that histologically and clinically resembles epithelial ovarian cancer.CASE PRESENTATION: We are reporting a case of a 62-year-old, postmenopausal women with primary fallopian tube carcinoma of the right fallopian tube in stage IA. The patient has lower abdominal pain, watery vaginal discharge and repeated episodes of bleeding from the vagina. The clinical and radiological findings suggested a right adnexal tumour with elevated CA-125 levels. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy and peritoneal washing were performed. Pathologic confirmation of primary serous cystadenocarcinoma of the right fallopian tube was made. Peritoneal washings were negative for malignancy. FIGO stage was considered as IA, and the patient received no courses of chemotherapy and postoperative radiation because she refused it. Ten months after initial surgery, the patient is alive and in good condition.CONCLUSION: Cytoreduction surgery followed by adequate cycles of chemotherapy is an important strategy to improve patients’ prognosis.

scholarly journals A rare presentation of a pyosalpinx in a post-menopausal woman

2018 ◽  
Vol 7 (8) ◽  
pp. 3381
Author(s):  
Ashwin Rao ◽  
Reddi Rani ◽  
Setu Rathod
Keyword(s):  
Fallopian Tube ◽  
Female Genital Tract ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Menopausal Woman ◽  
Fallopian Tube Carcinoma ◽  
Rare Presentation ◽  
Rare Tumour ◽  
Primary Fallopian Tube Carcinoma ◽  
Loss Of Appetite

Primary fallopian tube carcinoma is a rare tumour of the female genital tract with an incidence of 0.1-1.8% of all genital malignancies, which is generally an intra-operative or a histological diagnosis.  It is a tumour that resembles epithelial ovarian cancer. A 61-year-old postmenopausal woman presented with complaints of continuous bleeding per vaginum with history of loss of appetite and weight for 6 months. She was also a known diabetic and hypertensive. On examination, per abdominal, per speculum and per vaginal findings were unremarkable.  A transvaginal ultrasonography done previously showed fluid in the endometrial cavity suggestive of hematometra/pyometra due to cervical stenosis. A fractional curettage done previously had shown strips of acanthotic squamous epithelium in the endocervical curetting.   She underwent abdominal hysterectomy with bilateral salpingo ovariectomy. Histopathological findings were suggestive of primary fallopian tube adenocarcinoma. Hence the patient was advised chemotherapy followed by a second look laparotomy. Preoperative diagnosis of fallopian tube carcinoma is difficult due to the silent course of this neoplasm and is usually first appreciated at the time of operation or by a pathologist. The treatment approach is similar to that of ovarian carcinoma, and it should consist of a total abdominal hysterectomy with bilateral salpingo-ovariectomy, omentectomy and lymph node dissection from the pelvic and the para-aortic regions.

Preoperative and postoperative CA-125 serum levels in primary Fallopian tube carcinoma

1994 ◽  
Vol 255 (2) ◽  
pp. 65-68 ◽  
Author(s):  
A. C. Rosen ◽  
M. Klein ◽  
H. R. Rosen ◽  
A. H. Graf ◽  
M. Lahousen ◽  
...  
Keyword(s):  
Fallopian Tube ◽  
Serum Levels ◽  
Ca 125 ◽  
Fallopian Tube Carcinoma ◽  
Primary Fallopian Tube Carcinoma

Preoperative and postoperative CA-125 serum levels in primary Fallopian tube carcinoma

1994 ◽  
Vol 255 (2) ◽  
pp. 65-68 ◽  
Author(s):  
A. C. Rosen ◽  
M. Klein ◽  
H. R. Rosen ◽  
A. H. Graf ◽  
M. Lahousen ◽  
...  
Keyword(s):  
Fallopian Tube ◽  
Serum Levels ◽  
Ca 125 ◽  
Fallopian Tube Carcinoma ◽  
Primary Fallopian Tube Carcinoma

Primary fallopian tube carcinoma presenting with a sinus in the posterior portion of cervix

2004 ◽  
Vol 14 (1) ◽  
pp. 166-168
Author(s):  
Y. Khan ◽  
A. N. Haq ◽  
R. Nasar
Keyword(s):  
Adjuvant Chemotherapy ◽  
Ovarian Carcinoma ◽  
Surgical Resection ◽  
Fallopian Tube ◽  
Vaginal Discharge ◽  
Unusual Presentation ◽  
Rare Tumor ◽  
Fallopian Tube Carcinoma ◽  
Posterior Portion ◽  
Primary Fallopian Tube Carcinoma

Primary fallopian tube carcinoma is an aggressive but rare tumor. This is an unusual presentation of papilliferous tubal carcinoma presenting with vaginal discharge through a large sinus approximately 2–3 cm in size, located posterior to the neck of cervix. Surgery was undertaken with the initial diagnosis of primary ovarian carcinoma and the fistula was left to heal spontaneously. Surgical resection was followed by adjuvant chemotherapy. The patient is doing well after the therapy.

Primary fallopian tube carcinoma associated with ovulation induction; a case report

2008 ◽  
Vol 18 (6) ◽  
pp. 1360-1363 ◽  
Author(s):  
A. Deliveliotou ◽  
D. Hassiakos ◽  
S. Fotiou ◽  
E. Karvouni ◽  
G. Creatsas
Keyword(s):  
Fallopian Tube ◽  
Ovulation Induction ◽  
Gynecological Cancer ◽  
Total Abdominal Hysterectomy ◽  
Induction Treatment ◽  
Endometrioid Adenocarcinoma ◽  
Fallopian Tube Carcinoma ◽  
Adnexal Masses ◽  
Fertility Drugs ◽  
Primary Fallopian Tube Carcinoma

The potential relationship between ovulation induction and gynecological cancer has been raised recently. Primary fallopian tube carcinoma (PFTC) is an uncommon malignancy, not previously associated with fertility drugs use. We describe a case of a 38-year-old woman with primary infertility and a history of three ovulation inductions with gonadotropin-releasing hormone agonist and gonadotrophins, referred for treatment of bilateral ovarian cysts, which were discovered in the beginning of the last cycle. During laparotomy, bilateral adnexal masses were identified, presumed to be of ovarian origin, and total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy, and retroperitoneal lymph nodes sampling were performed. Histologic examination showed a primary right fallopian tube endometrioid adenocarcinoma and bilateral adnexal endometriosis. Surgery was followed by six cycles of combination chemotherapy using paclitaxel and carboplatin without significant complications. Although evidence of a direct causal link between ovarian stimulation and PFTC does not yet exist, this case highlights the importance for careful evaluation of all discovered adnexal masses in women undergoing ovulation induction treatment.

scholarly journals Case Report: Frontoparietal Metastasis From a Primary Fallopian Tube Carcinoma

2021 ◽  
Vol 8 ◽  
Author(s):  
Anthony I. Jang ◽  
Joshua D. Bernstock ◽  
David J. Segar ◽  
Marcello Distasio ◽  
Ursula Matulonis ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Metastasis ◽  
Fallopian Tube ◽  
Female Genital Tract ◽  
Fallopian Tube Carcinoma ◽  
Early Screening ◽  
Fallopian Tube Cancer ◽  
Primary Fallopian Tube Carcinoma ◽  
The Central Nervous System

Background: Metastatic brain tumors typically arise from primary malignancies of the lung, kidney, breast, skin, and colorectum. Brain metastases originating from malignancies of the female genital tract are extremely rare. We present a case of fallopian tube brain metastasis and in so doing review the pertinent literature.Case Description: We describe a 59-year-old patient with a history of fallopian tube carcinoma who presented with an incidentally identified left frontal brain mass. MRI demonstrated an enhancing lesion in the left centrum semiovale with a second enhancing lesion noted in the cerebellar vermis. She underwent a left parietal craniotomy for resection of the dominant and clinically symptomatic lesion. Immunohistochemical stains were positive for PAX8 and p53, confirming fallopian tube origin.Conclusions: Fallopian tube cancer brain metastasis is extremely uncommon. We highlight the treatment and surgical resection of this patient's BRCA1 metastatic fallopian lesion and systematically review the literature regarding the pathogenesis, diagnosis, treatment, and histologic characteristics of the previously identified fallopian tube metastases to the central nervous system. The optimal course of treatment for brain metastasis of fallopian tube carcinoma has not been clearly defined due in part to the rarity of this condition. Consistent with BRCA1 neoplasms involving the breast and ovaries, the BRCA1 status of the patient's primary tumor likely increased the risk of central nervous system dissemination. This highlights a potential benefit of early screening of individuals with metastatic gynecologic malignancies associated with BRCA1 in the absence of any neurological symptoms.

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