Optimum dose setting test by a double blind test of TJN-318 cream for dermatomycosis.

1992 ◽  
Vol 54 (5) ◽  
pp. 962-976 ◽  
Author(s):  
HISASHI TAKAHASHI
Keyword(s):  
Optimum Dose ◽  
Double Blind ◽  
Blind Test

scholarly journals Breast Cancer Detection from a Urine Sample by Dog Sniffing: A Preliminary Study for the Development of a New Screening Device and a Literature Review

Biology ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 517
Author(s):  
Shoko Kure ◽  
Shinya Iida ◽  
Marina Yamada ◽  
Hiroyuki Takei ◽  
Naoyuki Yamashita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Cancer Patients ◽  
Urine Sample ◽  
Urine Samples ◽  
Breast Cancer Patients ◽  
Double Blind ◽  
Blind Test ◽  
Preliminary Study ◽  
Detect Breast Cancer

Background: Breast cancer is a leading cause of cancer death worldwide. Several studies have demonstrated that dogs can sniff and detect cancer in the breath or urine sample of a patient. This study aims to assess whether the urine sample can be used for breast cancer screening by its fingerprints of volatile organic compounds using a single trained sniffer dog. This is a preliminary study for developing the “electronic nose” for cancer screening. Methods: A nine-year-old female Labrador Retriever was trained to identify cancer from urine samples of breast cancer patients. Urine samples from patients histologically diagnosed with primary breast cancer, those with non-breast malignant diseases, and healthy volunteers were obtained, and a double-blind test was performed. Total of 40 patients with breast cancer, 142 patients with non-breast malignant diseases, and 18 healthy volunteers were enrolled, and their urine samples were collected. Results: In 40 times out of 40 runs of a double-blind test, the trained dog could correctly identify urine samples of breast cancer patients. Sensitivity and specificity of this breast cancer detection method using dog sniffing were both 100%. Conclusions: The trained dog in this study could accurately detect breast cancer from urine samples of breast cancer patients. These results indicate the feasibility of a method to detect breast cancer from urine samples using dog sniffing in the diagnosis of breast cancer. Although the methodological standardization is still an issue to be discussed, the current result warrants further study for developing a new breast cancer screening method based on volatile organic compounds in urine samples.

scholarly journals Investigation on effects of Styptanon on hemorrhage during operation and after operative edema with a double blind test

1972 ◽  
Vol 18 (5) ◽  
pp. 553-559
Author(s):  
Hiroyasu NOMA ◽  
Teruhiko KAWABATA ◽  
Shigeru MIYACHI ◽  
Masahiro Tooi
Keyword(s):  
Double Blind ◽  
Blind Test

A Partially Blind Study

PEDIATRICS ◽  
1983 ◽  
Vol 71 (4) ◽  
pp. 668-668
Author(s):  
L. LOTHE ◽  
T. LINDBERG ◽  
I. JAKOBSSON
Keyword(s):  
Blind Study ◽  
Cow’S Milk ◽  
Infantile Colic ◽  
Double Blind ◽  
Blind Test ◽  
Cow's Milk

In Reply.— In reply to Forsyth we want to refer to our recent publication in this journal. Once again we emphasize that our conclusion that cow's milk seems to be one major factor in causing infantile colic is based on the results of the whole study (ie, not only the double-blind test, but also the outcome of the cow's milk challenges at follow-up). Concerning the 18% (11 infants) who did not react adversely to soy formula, seven infants received it as the first challenge and four as the second.

Age and growth of blue grenadier, Macruronus novaezelandiae (Hector), in south-eastern Australian waters

1987 ◽  
Vol 38 (5) ◽  
pp. 625 ◽  
Author(s):  
TJ Kenchington ◽  
O Augustine
Keyword(s):  
Growth Parameters ◽  
Growth Curves ◽  
Growth Patterns ◽  
Age And Growth ◽  
Double Blind ◽  
Blind Test ◽  
Thin Sections ◽  
South Eastern ◽  
Weight Data ◽  
Immature Fish

Blue grenadier, Macruronus novaezelandiae, from south-eastern Australian waters were aged, using their otoliths (whole and in transverse thin sections). The greatest recorded age was 25 years. A double blind test showed that the recorded ages were sufficiently reproducible to use in fitting growth curves (Index of Average Percent Error: 8%), but not sufficiently so to assign individuals to particular year-classes. Von Bertalanffy growth curves were fitted to both length and weight data. For males, Lt = 90.7 (1 - exp[-0.256(t + 1.21)]} and Wt = 2.62 (1 - exp[-0.277(t + 1.39)]}3. For females, Lt = 99.3 {l - exp[-0.203(t + 1.48)]} and Wt = 4.16{1 - exp[-0.157(t + 2.93)]}3. L is the length in centimetres, W is the weight in kilograms and t is the age in years. A comparison with length-frequency modes validated the growth curves for immature fish, but no validation was possible for the adults. The $exes have qignificantly different growth patterns. Their growth parameters are typical of those of commercially exploited, temperate gadoid fishes and show no modification for the deep-water zone inhabited by blue grenadier.

The Effectiveness of Lactobacillus Beverages in Controlling Infections among the Residents of an Aged Care Facility: A Randomized Placebo-Controlled Double-Blind Trial

2015 ◽  
Vol 68 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Satoru Nagata ◽  
Takashi Asahara ◽  
Chongxin Wang ◽  
Yumi Suyama ◽  
Osamu Chonan ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Care Facility ◽  
The Elderly ◽  
Fermented Milk ◽  
Aged Care ◽  
Double Blind ◽  
Blind Test ◽  
Staff Members ◽  
Significant Difference ◽  
Bowel Movements

Backgrounds/Aims: To clarify the usefulness of Lactobacillus casei strain Shirota (LcS)-fermented milk in the normalization of bowel movements and improvement of infection control for the elderly residents and staff of facilities for the elderly. Methods: A randomized placebo-controlled double-blind test was performed among the elderly residents (average age, 85) and staff members (average age, 37) of facilities for the elderly. The participants randomly received either LcS-fermented milk or a placebo beverage once daily for 6 months. Clinical data and enteric conditions were compared between the 2 groups. Results: A significantly lower incidence of fever and improved bowel movements were seen in the LcS-fermented milk group (n = 36) in comparison to the placebo group (n = 36). The numbers of Bifidobacterium and Lactobacillus were significantly higher (p < 0.01), the numbers of destructive bacteria such as Clostridium difficile were significantly lower (p < 0.05), and the fecal acetic acid concentration and total acidity were significantly higher in the LcS group. A significant difference in the intestinal microbiota, fecal acetic acid, and pH was also observed between the LcS and placebo groups among the facility's staff members. Conclusions: The long-term consumption of LcS-fermented milk may be useful for decreasing the daily risk of infection and improving the quality of life among the residents and staff of facilities for the elderly.

Sign in / Sign up

Export Citation Format

Share Document