In atopic dermatitis patients, immunoglobulin A secretion to a body surface lowers.

1994 ◽  
Vol 56 (5) ◽  
pp. 919-926
Author(s):  
SHUHEI IMAYAMA
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L. Orivuori ◽  
G. Loss ◽  
C. Roduit ◽  
J.-C. Dalphin ◽  
M. Depner ◽  
...  

2021 ◽  
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Mark Boguniewicz ◽  
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Jamie Weisman ◽  
Lindsey Strowd ◽  
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Mirjam J. Knol ◽  
Inge M. Haeck ◽  
Carla A.F.M. Bruijnzeel-Koomen ◽  
Suzanne G.M.A. Pasmans

2012 ◽  
Vol 87 (3) ◽  
pp. 361-368 ◽  
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Ana Paula Dornelles da Silva Manzoni ◽  
Rita Langie Pereira ◽  
Roberta Zaffari Townsend ◽  
Magda Blessmann Weber ◽  
Aline Rodrigues da Silva Nagatomi ◽  
...  

BACKGROUND: The skin is the primary interface of the human being with the external environment and the presence of skin diseases can have substantial effects on the quality of life. OBJECTIVE: This study aims to make a comparative evaluation of the quality of life of pediatric patients with atopic dermatitis, psoriasis and vitiligo and correlate the findings with the total body surface and the areas with the disease exposed to view. METHODS: The sample consisted of 118 patients with atopic dermatitis, vitiligo and psoriasis, aged between 5 and 16 years, who were asked to answer the Children's Dermatology Life Quality Index (CDLQI) questionnaire. A dermatological examination for the measurement of total body surface affected by the disease was performed. RESULTS: The three groups showed an impaired quality of life. Patients with atopic dermatitis and psoriasis showed a significantly greater impact on the QoL than the group with vitiligo. There is a trend towards impaired quality of life in patients from the three groups of dermatoses, which is related to increments in both the total affected area and affected area exposed to view (r = 0.428 and p <0.001, r = 0.381 and p <0.001, respectively). CONCLUSION: The assessed children had impaired quality of life. However, there is a significantly greater impact in the groups with atopic dermatitis and psoriasis than in the group with vitiligo. This may be due to lack of symptoms in vitiligo and the fact this group presented a statistically smaller affected body surface than the other two groups.


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