scholarly journals Comment on Lachin et al. Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial. Diabetes Care 2017;40:777–783

Diabetes Care ◽  
2017 ◽  
Vol 40 (11) ◽  
pp. e164-e164 ◽  
Author(s):  
Jesper Fleischer ◽  
Simon Lebech Cichosz ◽  
Troels Krarup Hansen
2020 ◽  
Vol 4 (6) ◽  
pp. 324-328
Author(s):  
A.R. Volkova ◽  
◽  
M.E. Chernaya ◽  
V.S. Mozgunova ◽  
M.B. Durdyeva ◽  
...  

Background: currently, the level of HbA1c does not necessarily allow for the understanding of glycemic control. Considering this, glycemic variability (GV) is extensively studied in recent years. Psychological component has a significant impact on GV as the fear of hypoglycemia (FOH) and its consequences can reduce the motivation for achieving target glycemia and HbA1c as well as adherence to treatment.Aim: to assess GV in patients with type 1 diabetes with the elevated and target levels of HbA1c and to analyze the effect of FOH on diabetes control.Patients and Methods: 78 patients with type 1 diabetes who received insulin therapy (multiple daily injections or continuous subcutaneous insulin infusion) were enrolled. All patients were divided into two groups based on HbA1c levels, i.e., group 1 (patients who achieved individual HbA1c target level, n=13) and group 2 (patients who did not achieve individual HbA1c target level, n=65). HbA1c levels and GV were measured in all patients using iPRO™2 Professional CGM system (Medtronic, Ireland). In addition, FOH was evaluated using the Hypoglycemia Fear Survey II (HFS-II).Results: in group 1, time in-range was significantly higher (p=0.013) while daily GV was significantly lower (p=0.023) than in group 2. HbA1c levels, the rate of severe hypoglycemia, and diabetes duration were lower among the patients with lower levels of FOH.Conclusion: studying GV can provide better understanding of diabetes control in patients with any HbA1c level. Optimized treatment strategy using HFS-II can attenuate the effects of frequent hypoglycemia on GV and HbA1c levels and improve treatment efficacy.KEYWORDS: glycemic variability, glycated hemoglobin, diabetes, continuous glucose monitoring, hypoglycemia.FOR CITATION: Volkova A.R., Chernaya M.E., Mozgunova V.S. et al. Impact of glycemic variability and the fear of hypoglycemia on type 1 diabetes control. Russian Medical Inquiry. 2020;4(6):324–328. DOI: 10.32364/2587-6821-2020-4-6-324-328.


Diabetes Care ◽  
2017 ◽  
Vol 40 (6) ◽  
pp. 777-783 ◽  
Author(s):  
John M. Lachin ◽  
Ionut Bebu ◽  
Richard M. Bergenstal ◽  
Rodica Pop-Busui ◽  
F. John Service ◽  
...  

2018 ◽  
Author(s):  
Jan Idkowiak ◽  
Sabba Elhag ◽  
Vrinda Saraff ◽  
Renuka Dias ◽  
Timothy Barrett ◽  
...  

Author(s):  
Martín Borja Sanz ◽  
Gimeno Sergio Roman ◽  
Peteiro Miranda Carlos Miguel ◽  
Ortez Toro Jose Jorge ◽  
Ana Agudo ◽  
...  

2018 ◽  
Vol 14 (4) ◽  
pp. 395-403 ◽  
Author(s):  
Karem Mileo Felício ◽  
Ana Carolina Contente Braga de Souza ◽  
Joao Felicio Abrahao Neto ◽  
Franciane Trindade Cunha de Melo ◽  
Carolina Tavares Carvalho ◽  
...  

Author(s):  
David S. Greene ◽  
Nancy Dunavant King

Abstract There is increasing evidence of specific medical and psychological benefits associated with humor within diabetes populations. The benefits of maintaining good diabetes control are also well established. The more general relationship between humor and diabetes control however remains unexplored. The purpose of this study was to examine if there was a difference between people with diabetes with an A1C ≤ 6.99% versus those ≥7.0% on four disparate types of humor. The sample consisted of 284 participants, 65.5% with type 1 diabetes, 68.3% female, 89.1% Caucasian, and 68.7% college educated. Participants completed the Humor Styles Questionnaire (HSQ) and were divided into two groups, A1C ≤ 6.99% and A1C ≥ 7.0%. The A1C ≤ 6.99% group scored significantly higher on both types of positive humor, affiliative humor (P < 0.01) and self-enhancing humor (P < 0.05). There was no significant difference between participants on either type of negative humor, aggressive humor (P > 0.05) or self-defeating humor (P > 0.05). Results indicate that good control (A1C ≤ 6.99%) is associated with positive humor. These findings provide evidence that there is an association between American Diabetes Association recommended levels of control and positive humor styles. Implications regarding positive humor and good diabetes control are discussed.


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