A single home visit by an occupational therapist reduces the risk of falling after hip fracture in elderly women: A quasi-randomized controlled trial

Abstract Background Interorgan communication networks established during exercise in several different tissues can be mediated by several exercise-induced factors. Therefore, the present study aimed to investigate the effects of resistance-type training using elastic band-induced changes of myomiRs (i.e., miR-206 and miR-133), vitamin D, CTX-I, ALP, and FRAX® score in elderly women with osteosarcopenic obesity (OSO). Methods In this randomized controlled trial, 63 women (aged 65–80 years) with Osteosarcopenic Obesity were recruited and assessed, using a dual-energy X-ray absorptiometry instrument. The resistance-type training via elastic bands was further designed three times per week for 12-weeks. The main outcomes were Fracture Risk Assessment Tool score, bone mineral content, bone mineral density, vitamin D, alkaline phosphatase, C-terminal telopeptides of type I collagen, expression of miR-206 and miR-133. Results There was no significant difference between the study groups in terms of the Fracture Risk Assessment Tool score (p = 0.067), vitamin D (p = 0.566), alkaline phosphatase (p = 0.334), C-terminal telopeptides of type I collagen (p = 0.067), microR-133 (p = 0.093) and miR-206 (p = 0.723). Conclusion Overall, the results of this study illustrated 12-weeks of elastic band resistance training causes a slight and insignificant improvement in osteoporosis markers in women affected with Osteosarcopenic Obesity. Trial registration Randomized controlled trial (RCT) (Iranian Registry of Clinical Trials, trial registration number: IRCT20180627040260N1. Date of registration: 27/11/2018.

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A family care model for older persons with hip-fracture and cognitive impairment: A randomized controlled trial

International Journal of Nursing Studies ◽

10.1016/j.ijnurstu.2021.103995 ◽

2021 ◽

pp. 103995

Author(s):

Ming-Yueh Tseng ◽

Ching-Tzu Yang ◽

Jersey Liang ◽

Huei-Ling Huang ◽

Li-Min Kuo ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Cognitive Impairment ◽

Hip Fracture ◽

Older Persons ◽

Controlled Trial ◽

Family Care ◽

Care Model ◽

Randomized Controlled

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Retracted: Alendronate and vitamin D2 for prevention of hip fracture in Parkinson's disease: A randomized controlled trial

Movement Disorders ◽

10.1002/mds.20825 ◽

2006 ◽

Vol 21 (7) ◽

pp. 924-929 ◽

Cited By ~ 37

Author(s):

Yoshihiro Sato ◽

Jun Iwamoto ◽

Tomohiro Kanoko ◽

Kei Satoh

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Randomized Controlled Trial ◽

Hip Fracture ◽

Controlled Trial ◽

Vitamin D2 ◽

Randomized Controlled

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Six Versus 12 Weeks of Outpatient Physical Therapy Including Progressive Resistance Training in Cognitively Intact Older Adults After Hip Fracture: A Multicenter Randomized Controlled Trial

The Journals of Gerontology Series A ◽

10.1093/gerona/glab256 ◽

2021 ◽

Author(s):

Jan A Overgaard ◽

Thomas Kallemose ◽

Kathleen K Mangione ◽

Morten T Kristensen

Keyword(s):

Older Adults ◽

Randomized Controlled Trial ◽

Hip Fracture ◽

Physical Therapy ◽

Controlled Trial ◽

Community Dwelling ◽

Walking Distance ◽

Randomized Controlled ◽

Multicenter Randomized Controlled Trial ◽

Cognitively Intact

Abstract Background Recovery of function and regaining muscle strength are challenging after hip fracture. We compared the effectiveness of a 12- versus 6-week outpatient physical therapy program with progressive resistive training (PRT) to increase strength and physical performance. Methods This parallel, superiority, 2-group randomized controlled trial was conducted in 4 clinics that enrolled community-dwelling, cognitively intact older adults (+60 years) with a surgical repair of a hip fracture and no major medical conditions. Participants received 12 or 6 weeks of PRT and standardized physical therapy, twice weekly. Pain was monitored throughout. Primary outcome was the change in the 6-minute walk test (6MWT) from baseline to 12-week follow-up. Randomization via a computer-generated allocation sequence was implemented using sealed, sequentially numbered opaque envelopes and assessors were blinded to group assignment. Results Participants (81% women) with a mean (SD) age of 77 (8.1) years were enrolled at an average of 18 days after hip fracture surgery and randomized into a 12-week group (n = 50) or a 6-week group (n = 50). Mean (SD) change scores in the 6MWT were 143.8 (81.1) and 161.5 (84.1) m in the 12- and 6-week groups, respectively (both exceeding the minimal clinically important difference of 55 m). The mean between-group difference was −17.7 m (95% CI −50.1, 14.8). Pain during training did not exceed moderate levels nor increase as training intensity increased. Conclusion Twelve weeks of physical therapy with PRT was not superior to 6 weeks in improving walking distance. Hip fracture-related pain was relatively low and indicated strength testing and training was well tolerated. Clinical Trials Registration Number: NCT01174589

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