Real-life use of phototherapy in early-stage mycosis fungoides from the Cutaneous Lymphoma Commission of the Italian Lymphoma Foundation: results of a web-based survey

Author(s):  
Vieri Grandi ◽  
Paolo Fava ◽  
Serena Rupoli ◽  
Silvia Alberti Violetti ◽  
Lucia Canafoglia ◽  
...  
2018 ◽  
Vol 93 (5) ◽  
pp. 680-685 ◽  
Author(s):  
Gustavo Moreira Amorim ◽  
João Paulo Niemeyer Corbellini ◽  
Danielle Carvalho Quintella ◽  
Tullia Cuzzi ◽  
Márcia Ramos-e-Silva

2010 ◽  
Vol 14 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Elena Pope ◽  
Sheila Weitzman ◽  
Bo Ngan ◽  
Scott Walsh ◽  
Kimberly Morel ◽  
...  

Background/Objectives: There are limited data on the clinical presentation and progression of pediatric cutaneous lymphoma. This study focuses on the clinical characteristics of pediatric patients with mycosis fungoides (MF). Materials and Methods: This descriptive study presents clinical characteristics of 22 pediatric patients with MF, enrolled in the international Childhood Registry for Cutaneous Lymphomas (CRCL). Results: The mean ages at onset and at diagnosis were 7.5 (SD 3.8 years) years and 9.9 (SD 3.4) years, respectively. The most common MF presentation was patch stage (68%), followed by hypopigmentation (59%) and plaque stage disease (50%). Epidermotropism and lymphocytic atypia were the most common pathologic features, found in 89% and 85%, respectively. Cerebriform nuclei were noted in 42%, and Pautrier microabscesses were seen in 16% of cases. A cytotoxic pattern was more commonly seen (67% vs 33%), and clonality was detected in 21% (3 of 14) of patients. All patients presented with early-stage disease and received skin-directed therapy (topical steroids, 73%; light therapy, 54%; or combination therapy, 35%). Conclusions: Pediatric patients with MF present in the first decade of life, with early-stage disease and unusual forms such as hypopigmented variant. Further patient enrolment will provide information regarding natural history, treatment response, and overall prognosis of pediatric cutaneous T-cell lymphoma (CTCL).


Author(s):  
M.-O. Löwner ◽  
N. C. Bandelow ◽  
M. Gerke ◽  
F. Hillen ◽  
L. Klein ◽  
...  

Abstract. Planning and realization of large infrastructure takes a lot of time due to public discussion and may be reduced by active citizen participation in an early stage of project. Insufficient or late citizen participation in large-sized projects is being held liable to effect escalation, which, again may lead to enormous delays and costs. In this contribution we propose and sketching out an internet-based planning tool, which enables the planning of large infrastructure by concerned citizens and. Therefore, it serves to objectify the debate. Within an interdisciplinary group legal issues and planning expertise will be formulized and implemented as a tool suite on a server using open source technologies. A geodatabase holds project related open and official geodata. For planning reasons, recent technology of unmanned aerial vehicle (UAV) data acquisition and feature extraction methods will be used to complement planning data. Geodata and tools will be accessed by an easy-to-use client-based mapping tool that also manages the evaluation of the users planning proposals on a server. Based on a real-life project from railway infrastructure the web-based planning tool will be valuated with real applicants.


Healthcare ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 960
Author(s):  
Hudson D. Spangler ◽  
Miguel A. Simancas-Pallares ◽  
Jeannie Ginnis ◽  
Andrea G. Ferreira Zandoná ◽  
Jeff Roach ◽  
...  

The importance of visual aids in communicating clinical examination findings or proposed treatments in dentistry cannot be overstated. Similarly, communicating dental research results with tooth surface-level precision is impractical without visual representations. Here, we present the development, deployment, and two real-life applications of a web-based data visualization informatics pipeline that converts tooth surface-level information to colorized, three-dimensional renderings. The core of the informatics pipeline focuses on texture (UV) mapping of a pre-existing model of the human primary dentition. The 88 individually segmented tooth surfaces receive independent inputs that are represented in colors and textures according to customizable user specifications. The web implementation SculptorHD, deployed on the Google Cloud Platform, can accommodate manually entered or spreadsheet-formatted tooth surface data and allows the customization of color palettes and thresholds, as well as surface textures (e.g., condition-free, caries lesions, stainless steel, or ceramic crowns). Its current implementation enabled the visualization and interpretation of clinical early childhood caries (ECC) subtypes using latent class analysis-derived caries experience summary data. As a demonstration of its potential clinical utility, the tool was also used to simulate the restorative treatment presentation of a severe ECC case, including the use of stainless steel and ceramic crowns. We expect that this publicly available web-based tool can aid clinicians and investigators deliver precise, visual presentations of dental conditions and proposed treatments. The creation of rapidly adjustable lifelike dental models, integrated to existing electronic health records and responsive to new clinical findings or planned for future work, is likely to boost two-way communication between clinicians and their patients.


Sign in / Sign up

Export Citation Format

Share Document