Bladder recurrence of primary upper tract urinary carcinoma following nephroureterectomy, and risk of upper urinary tract recurrence after ureteral stent positioning in patients with primary bladder cancer

2019 ◽  
Vol 71 (3) ◽  
Author(s):  
Francesco A. Mistretta ◽  
Diego M. Carrion ◽  
Sebastiano Nazzani ◽  
Juan L. Vásquez ◽  
Cristian Fiori ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urinary Tract ◽  
Upper Urinary Tract ◽  
Ureteral Stent ◽  
Upper Tract ◽  
Primary Bladder ◽  
Bladder Recurrence ◽  
Primary Bladder Cancer

Upper urinary tract cancer: Prognostic factors for bladder tumours development and systemic relapse

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 14560-14560
Author(s):  
F. Merlin ◽  
M. Riolfi ◽  
T. Sava ◽  
F. Consoli ◽  
C. Griso ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Factors ◽  
Urinary Tract ◽  
Vascular Invasion ◽  
Superficial Bladder Cancer ◽  
Transitional Cell ◽  
Upper Urinary Tract ◽  
Upper Tract ◽  
Well Differentiated ◽  
Systemic Relapse

14560 Background: Transitional cell carcinomas (TCC) of the renal pelvis and ureter are relatively uncommon. An important characteristic of TCC is multifocality throughout the all urinary tract simultaneously and/or subsequently. To clarify the association between UTTCC and bladder tumors, we retrospectively analysed 86 patients with UTTCC in order to evaluate prognostic factors for recurrence and to identify risk factors for development of bladder cancers. Methods: All 86 upper tract transitional cell carcinoma patients (pts) were treated surgically between January 1988 and July 2005. Median age was 69 years (range: 34–91). We observed a male predominance (71%) and 78% of patients were heavy smokers. Forty-five (52.3%) patients had a diagnosis of bladder transitional carcinoma. The median age of this group of patients was 70 range 40–87). In fifteen cases (17%), bladder tumour occurred first than upper tract neoplasia; in 14 patients bladder and upper tract tumours were synchronous. Results: Median survival was 97 months; 49 (57%) patients are alive and 43 are disease-free. Grading, stage T, lympho-vascular invasion and squamous differentiation were significant prognostic factors for systemic relapse (p < 0.05). Twenty-eight pts (32.5%) developed subsequent transitional bladder cancer after a median time of 12 months; multifocality of primitive tumours was significant predictive factor. Invasive UTTCC were less likely associated with bladder cancer. We observed that superficial bladder cancer developed more frequently in pts with well differentiated (G1–2) primitive cancer (90% of cases), without lympho-vascular invasion and with history of heavy smoke exposition. Conclusions: In our study, T, N and G confirmed to be the most important prognostic factors for systemic relapse. Lympho-vascular invasion highly predicts metastasis. Our analysis highlights that upper urinary tract cancers seem to have different history and different pattern of association with bladder tumours, according to specific prognostic factors. The development of recurrent superficial bladder cancer is more frequently associated with small well differentiated multifocal upper tract tumours.Therefore follow-up should be oriented according to these characteristics. No significant financial relationships to disclose.

Upper tract surveillance in primary bladder cancer follow-up

2004 ◽  
Vol 94 (6) ◽  
pp. 790-792 ◽  
Author(s):  
Mohamed K. Enver ◽  
Paul D. Miller ◽  
Frank I. Chinegwundoh
Keyword(s):  
Bladder Cancer ◽  
Upper Tract ◽  
Primary Bladder ◽  
Primary Bladder Cancer

Upper Tract Tumors in Patients with Primary Bladder Cancer Followed for 15 Years

1996 ◽  
Vol 156 (4) ◽  
pp. 1286-1287 ◽  
Author(s):  
Harry W. Herr ◽  
Michael S. Cookson ◽  
Scott M. Soloway
Keyword(s):  
Bladder Cancer ◽  
Upper Tract ◽  
Primary Bladder ◽  
Primary Bladder Cancer

406: Upper Urinary Tract Recurrence Following Radical Cystectomy for Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 135-135
Author(s):  
Junya Furukawa ◽  
Hideaki Miyake ◽  
Kazushi Tanaka ◽  
Atsushi Takenaka ◽  
Isao Hara ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urinary Tract ◽  
Radical Cystectomy ◽  
Upper Urinary Tract

scholarly journals Ureteral Involvement and Diabetes Increase the Risk of Subsequent Bladder Recurrence after Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Che-Yuan Hu ◽  
Yu-Chieh Tsai ◽  
Shuo-Meng Wang ◽  
Chao-Yuan Huang ◽  
Huai-Ching Tai ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Urinary Tract ◽  
Urothelial Carcinoma ◽  
Cox Model ◽  
Medical Center ◽  
Upper Urinary Tract ◽  
Increased Risk ◽  
The Impact ◽  
Bladder Recurrence ◽  
Urinary Tract Urothelial Carcinoma

Objectives.To investigate the prognostic factors for bladder recurrence after radical nephroureterectomy (RNU) in patients with upper urinary tract urothelial carcinoma (UUT-UC).Methods.From 1994 to 2012, 695 patients with UUT-UC treated with RNU were enrolled in National Taiwan University Medical Center. Among them, 532 patients with no prior bladder UC history were recruited for analysis. We assessed the impact of potentially prognostic factors on bladder recurrence after RNU.Results.The median follow-up period was 47.8 months. In the Cox model, ureteral involvement and diabetes mellitus (DM) were significantly associated with a higher bladder recurrence rate in the multivariate analysis (hazard ratio [HR]: 1.838;P=0.003and HR: 1.821;P=0.010, resp.). In the Kaplan-Meier analysis, DM patients with concomitant ureteral UC experienced about a threefold increased risk of bladder recurrence as compared to those without both factors (HR: 3.222;P<0.001). Patients with either of the two risk factors experienced about a twofold increased risk as compared to those without both factors (with DM, HR: 2.184,P=0.024; with ureteral involvement, HR: 2.006,P=0.003).Conclusions.Ureteral involvement and DM are significantly related to bladder recurrence after RNU in patients with UUT-UC.

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