scholarly journals The Role of Positron Emission Tomography Imaging in the Risk-Adapted Treatment of Stage I-II Hodgkin's Lymphoma - A Retrospective Analysis

Author(s):  
Tom Rider
2012 ◽  
Vol 08 (02) ◽  
pp. 111
Author(s):  
Amanda F Cashen ◽  

Positron emission tomography (PET) is widely used in the diagnosis and response assessment after first-line treatment of Hodgkin’s lymphoma (HL). For the approximately 30 % of patients who relapse or have refractory disease, PET can provide valuable prognostic information during second-line therapy, at the time of autologous stem cell transplant (ASCT). Retrospective studies performed over the past decade have consistently found a significant association between a positive PET scan after salvage chemotherapy for HL and progression-free and overall survival after ASCT. In fact, the predictive value of pre-transplant PET appears higher than that of more traditional clinical risk factors. Unfortunately, there is little data to recommend the best treatment course for patients who have a positive pre-ASCT PET, and few studies have addressed the role of PET in other relapsed/refractory HL settings.


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