CLASSIFICATION OF GLOMERULONEPHRITIS: ON THE WAY AB EXTERIORIBUS AD INTERIORA (TO THE DISCUSSION ABOUT THE PROJECT OF MODERN CLASSIFICATION OF GLOMERULONEPHRITIS IN CHILDREN)

2018 ◽  
Vol 97 (5) ◽  
pp. 146-150
Author(s):  
A.V. Smirnov ◽  
Author(s):  
S. P. Oakley

After a brief introduction on stemmatic method, this book contains genealogical investigations of the textual traditions of Quintus Curtius Rufus and then Dictys Cretensis. The sections on each author begin with a list of MSS and incunables that will be discussed (they number just over 150 for Curtius, about 80 for Dictys) and then a survey of existing scholarship. There then follows the classification of the MSS and incunables; most of the MSS of both authors were produced in Italy in the fifteenth-century. In the section on Curtius MSS B = Bern, Burgerbibliothek 451, Br = Brussels 10161, and A= Paris, lat. 5720, owned by Petrarch are shown to have been very productive. For Dictys it is argued that a stemma codicum can be established. First witnesses related to G = Sankt Gallen, Stiftsbibliothek 197 (these include an important lost MS of Poggio) are discussed, then those related to MS E, the codex Aesinas, owned by Stefano Guarnieri. There follows discussion of the archetype, of the way in which proper attention to the stemma codicum can improve the text, and of the excerpts from Dictys found in MSS of Dares.


Author(s):  
M. Yu. Kharitonovа ◽  
◽  
N. A. Matsko ◽  

For resources in the exploration stage, the modern “Classification of reserves” requires determining the economic efficiency of development prospects. Calculations of the development efficiency are based on the development time, which is difficult to determine without technological projects and schemes due to insufficient initial data. The identification of development stages in the preliminary economic assessment is carried out on the basis of expert appraisals without precise criteria, by analogy with the fields under development. The article establishes empirical dependencies and shows the possibility of their use for express forecast of the period for finishing work on a field (deposit), duration of the main development period, duration of the increasing production stage. Dependencies allow solving the problem of constructing a production curve in conditions of limited geological data. The express method can be used at the macro level to develop strategies for the development of oil and gas regions and at the micro level in the economic assessment of the prospects for the development of objects.


2021 ◽  
pp. 39-44
Author(s):  
A. V. Ignatovsky

Objective. To present a variant of the modern classification of the processes occurring with lesions of the genitals, to draw specialists’ attention to the peculiarities and variety of causes leading to inflammation of the glans and foreskin, as well as to discuss topical issues of external therapy of balanopostitis.Material and methods. Data from modern studies and clinical guidelines were used in the preparation of the publication.Results. The variety of variants of lesions of the glans and foreskin can be due to a number of reasons and can be either an independent local process or a fragment of dermatosis, where it is possible to be affected in the form of balanoposthitis. Also, when examining and selecting therapy options, it is important to consider the possible role of microorganisms, whose spectrum as a cause of balanoposthitis varies from aerobic and anaerobic, to viral and fungal microflora. Treatment approaches are determined by the etiological factors.Conclusions. Balanoposthitis is a heterogeneous group of nosologies. The choice of treatment is based on the identified cause or empirically when possible. External therapy and hygiene constitute an essential part of treatment. When choosing drugs for topical glucocorticosteroids, preferenceshould be given to drugs with a high therapeutic index and low atrophogenic potential. Dysplastic processes of the penis are associated with human papillomavirus infection, the treatment of which can be both conservative and destructive.


2017 ◽  
Vol 33 (2) ◽  
pp. 137-140 ◽  
Author(s):  
Antonino Carbone ◽  
Annunziata Gloghini

“Ne è passata di acqua sotto i ponti.” It has been a long time since the diagnosis of Hodgkin lymphoma (HL) was exclusively based on the detection of typical Reed-Sternberg cells and the recognition of the characteristic morpho-histological background, as well as on the pathologist’s skill. The discovery of immunologic, molecular genetic and virologic biomarkers has provided an objective contribution to the diagnosis and a scientific basis for a modern classification of HL. Recent updates have clarified the nature of the so-called nodular lymphocyte predominant HL and its link to the T-cell/histiocyte-rich large B-cell lymphomas as well as its relationship with the lymphocyte-rich subset of classical HL (CHL). Molecular virology studies assessed a role for the Epstein-Barr virus in the pathogenesis of a fraction of CHL of the general population, and virtually in all cases of CHL occurring in people infected by HIV. Finally, immunologic and genetic findings corroborated the existence of grey zone lymphomas at the edges of CHL. Overall, these advances provided additional and useful information to address the treatment of patients affected by HL.


2009 ◽  
Vol 81 (3) ◽  
pp. 367-380 ◽  
Author(s):  
Luis E. C. Andrade

Human beings have taken successive approaches for the understanding and management of diseases. Initially brewed in supernatural concepts and mystical procedures, a vigorous scientific approach has emerged on the grounds of fundamental disciplines such as anatomy, microbiology, biochemistry, physiology, immunology, pathology, and pharmacology. The resulting integrated knowledge contributed to the current classification of diseases and the way Medicine is carried out today. Despite considerable progress, this approach is rather insufficient when it comes to systemic inflammatory conditions, such as systemic lupus erythematosus, that covers clinical conditions ranging from mild pauci-symptomatic diseases to rapidly fatal conditions. The treatment for such conditions is often insufficient and novel approaches are needed for further progress in these areas of Medicine. A recent breakthrough has been achieved with respect to chronic auto-inflammatory syndromes, in which molecular dissection of underlying gene defects has provided directions for target-oriented therapy. Such approach may be amenable to application in systemic auto-immune diseases with the comprehension that such conditions may be the consequence of interaction of specific environmental stimuli and an array of several and interconnected gene polymorphisms. On the bulk of this transformation, the application of principles of pharmacogenetics may lead the way towards a progressively stronger personalized Medicine.


2020 ◽  
Vol 69 ◽  
pp. 36-44
Author(s):  
Yarema Kravets’ ◽  

Purpose: The article is devoted to the Sorbian studies work of the Italian Slavic scholar of Lusatian origin Wolfango Giusti (1901-1980) “The Folk Lusatian Serbian Song” (1926), totally unknown in Ukrainian Slavic scholars’ circles. The author of a large number of Sorbian studies publications printed in the 1920s and 1930s in the pages of Italian Slavic editions, he became a true popularizer of Lusatian culture, and his works found a special reverberation in the research papers of authoritative Sorbian scholars. W. Giusti’s name as researcher and translator has recently been more frequently mentioned in Slavistic publications, his interest in Ukrainian poetry, esp. in the 1920s, is written about. The interest in W. Giusti’s literary legacy is linked, in particular, to his being interested in T. Shevchenko’s and M. Shashkevych’s lyrics. In the research under analysis, the Italian scholar stressed that “the soul of the Lusatian people has found its best and fullest expression in their folk song”. Also mentioned by W. Giusti were Ukrainian folk songs, rich in their multi-genre samples. Results: The paper presents a classification of the most characteristic folk songs, the classification coming to be basis-providing for the Italian scholar: W. Giusti relied on authoritative research papers, including those by the scholars K. Fiedler and B. Krawc. The Italian Slavicist acquaints us with songs of love between brother and sister, love songs about the way of life of the whole people, songs resonating with the motif of fidelity. Neither has the literary scholar bypassed the issue of the neighbouring peoples’ influence experienced by Lusatian culture, particularly that of a Germanic culture, providing some examples of a “spiritual analogy” with German folk songs. W. Giusti completed his short essay by promising to offer the reader, before long, “other genres of the extremely rich Lusatian folklore”. The promise came to be fulfilled as early as the next year, in the work published under the title “Folk Lusatian Serbian Songs”. Key words: Lusatian folklore, Wolfango Giusti, folk song, motif of fidelity/infidelity, dramatic mood, classification of songs, aspects of “Wendish” folklore, Germanic influence.


2021 ◽  
Author(s):  
Radoslaw Niewiadomski ◽  
Amrita Suresh ◽  
Alessandra Sciutti ◽  
Giuseppe DI Cesare

The form of an action, i.e. the way it is performed, conveys important information about the performer’s attitude. In this paper we investigate spatiotemporal characteristics of different gestures performed with specific vitality forms and we study whether it is possible to recognize these aspects of action automatically. As the first step, we created a new dataset of 7 gestures performed with a vitality form (gentle and rude) or without a vitality form (neutral, slow and fast). Thousand repetitions were collected from 2 professional actors. Next, we identified 22 features from the motion capture data. According to the results, vitality forms are not merely characterized by a velocity/acceleration modulation but by a combination of different spatiotemporal properties. We also perform automatic classification of vitality forms with F-score of 87.3%.


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