scholarly journals Current classification of macular neovascularization in the course of AMD based on the Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data

2021 ◽  
Vol 8 (1) ◽  
pp. 5-10
Author(s):  
Anna Piotrowicz ◽  
Katarzyna Paczwa ◽  
Joanna Gołębiewska ◽  
Radosław Różycki
Keyword(s):  
Macular Degeneration ◽  
Expert Panel ◽  
Vision Impairment ◽  
Age Related Macular Degeneration ◽  
Central Vision ◽  
Subretinal Neovascularization ◽  
Therapeutic Techniques ◽  
Age Related ◽  
Current Classification

Despite the improvement of diagnostic and therapeutic techniques age-related macular degeneration is still one of the main causes of central vision impairment. Throughout the years, the classification of subretinal neovascularization in the course of age-related macular degeneration has changed due to the advancement of diagnostic and therapeutic techniques. In 2020 an expert panel reached consensus on a new nomenclature for neovascularization in the course of age-related macular degeneration introducing the concept of macular neovascularization, which refers to each neovascularization in macula, regardless of the location.

scholarly journals Age-Related Macular Degeneration: Role of Oxidative Stress and Blood Vessels

2021 ◽  
Vol 22 (3) ◽  
pp. 1296
Author(s):  
Yue Ruan ◽  
Subao Jiang ◽  
Adrian Gericke
Keyword(s):  
Oxidative Stress ◽  
Macular Degeneration ◽  
Vascular Function ◽  
Vascular Dysfunction ◽  
Therapeutic Strategies ◽  
Vision Impairment ◽  
Age Related Macular Degeneration ◽  
Oxygen Species ◽  
Age Related

Age-related macular degeneration (AMD) is a common irreversible ocular disease characterized by vision impairment among older people. Many risk factors are related to AMD and interact with each other in its pathogenesis. Notably, oxidative stress and choroidal vascular dysfunction were suggested to be critically involved in AMD pathogenesis. In this review, we give an overview on the factors contributing to the pathophysiology of this multifactorial disease and discuss the role of reactive oxygen species and vascular function in more detail. Moreover, we give an overview on therapeutic strategies for patients suffering from AMD.

TYPE 2 (SUBRETINAL) NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION ASSOCIATED WITH PURE RETICULAR PSEUDODRUSEN PHENOTYPE

Retina ◽  
2016 ◽  
Vol 36 (3) ◽  
pp. 449-457 ◽  
Author(s):  
Jonathan Naysan ◽  
Jesse J. Jung ◽  
Kunal K. Dansingani ◽  
Chandrakumar Balaratnasingam ◽  
K. Bailey Freund
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Subretinal Neovascularization ◽  
Reticular Pseudodrusen ◽  
Age Related

scholarly journals Utility of Deep Learning Methods for Referability Classification of Age-Related Macular Degeneration

2018 ◽  
Vol 136 (11) ◽  
pp. 1305 ◽  
Author(s):  
Phillippe Burlina ◽  
Neil Joshi ◽  
Katia D. Pacheco ◽  
David E. Freund ◽  
Jun Kong ◽  
...  
Keyword(s):  
Deep Learning ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Learning Methods ◽  
Age Related

scholarly journals Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections

2019 ◽  
Vol 104 (5) ◽  
pp. 616-622 ◽  
Author(s):  
Ching-Yu Cheng ◽  
Ningli Wang ◽  
Tien Y Wong ◽  
Nathan Congdon ◽  
Mingguang He ◽  
...  
Keyword(s):  
Visual Acuity ◽  
East Asia ◽  
Macular Degeneration ◽  
Refractive Error ◽  
Temporal Trends ◽  
Vision Impairment ◽  
Age Related Macular Degeneration ◽  
Public Healthcare ◽  
Age Related ◽  
Uncorrected Refractive Error

BackgroundTo determine the prevalence and causes of blindness and vision impairment (VI) in East Asia in 2015 and to forecast the trend to 2020.MethodsThrough a systematic literature review and meta-analysis, we estimated prevalence of blindness (presenting visual acuity <3/60 in the better eye), moderate-to-severe vision impairment (MSVI; 3/60≤presenting visual acuity <6/18), mild vision impairment (mild VI: 6/18≤presenting visual acuity <6/12) and uncorrected presbyopia for 1990, 2010, 2015 and 2020. A total of 44 population-based studies were included.ResultsIn 2015, age-standardised prevalence of blindness, MSVI, mild VI and uncorrected presbyopia was 0.37% (80% uncertainty interval (UI) 0.12%–0.68%), 3.06% (80% UI 1.35%–5.16%) and 2.65% (80% UI 0.92%–4.91%), 32.91% (80% UI 18.72%–48.47%), respectively, in East Asia. Cataract was the leading cause of blindness (43.6%), followed by uncorrected refractive error (12.9%), glaucoma, age-related macular degeneration, corneal diseases, trachoma and diabetic retinopathy (DR). The leading cause for MSVI was uncorrected refractive error, followed by cataract, age-related macular degeneration, glaucoma, corneal disease, trachoma and DR. The burden of VI due to uncorrected refractive error, cataracts, glaucoma and DR has continued to rise over the decades reported.ConclusionsAddressing the public healthcare barriers for cataract and uncorrected refractive error can help eliminate almost 57% of all blindness cases in this region. Therefore, public healthcare efforts should be focused on effective screening and effective patient education, with access to high-quality healthcare.

scholarly journals Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration

Ophthalmology ◽  
2020 ◽  
Vol 127 (8) ◽  
pp. 1097-1104 ◽  
Author(s):  
Daniel Palanker ◽  
Yannick Le Mer ◽  
Saddek Mohand-Said ◽  
Mahiul Muqit ◽  
Jose A. Sahel
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Central Vision ◽  
Age Related
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