scholarly journals Guillain Barre Syndrome in a Young Man with SARSCoV-2: A Rare Association

2021 ◽  
Vol 08 (01) ◽  
pp. 22-25
Author(s):  
Naresh Kumar ◽  

Guillain Barre Syndrome (GBS) is usually a post-infectious autoimmune disease that manifests as acute ascending flaccid paralysis. The disease is usually uncommon. However, recently it was reported in a few COVID-19 cases before complete resolution of COVID symptoms. An association between olfactory-gustatory disturbances and sensory abnormalities is frequently observed in GBS with COVID-19. The electrophysiological studies usually reveal a demyelinating pattern. Respiratory involvement, as part of respiratory muscle paralysis or COVID-19 pneumonia, is associated with poor recovery in affected patients. Here, we present a case of a young man, pre-morbid healthy, who presented with GBS with mild COVID-19 infection. He successfully recovered after treatment with Intravenous immunoglobulin IVIg.

Author(s):  
Farman Khan ◽  
Praveen Sharma ◽  
Saurabh Pandey ◽  
Deepak Sharma ◽  
Vijayavarman V ◽  
...  

2019 ◽  
Vol 12 (4) ◽  
pp. e228845 ◽  
Author(s):  
Sajid Hameed ◽  
Sara Khan

Chikungunya (CHIK) viral fever is a self-limiting illness that presents with severe debilitating arthralgia, myalgia, fever and rash. Neurological complications are rare. We present a case of a 36-year-old woman who presented with acute onset progressive difficulty swallowing and left arm weakness. She was diagnosed with CHIK viral fever 4 weeks prior to admission. After investigations, she was diagnosed with a pharyngeal–cervical–brachial variant of Guillain-Barré syndrome. In hospital, she required ventilator support. Her condition improved after five sessions of intravenous immunoglobulin with almost complete resolution within 6 months of symptom onset. With frequent CHIK outbreaks, the neurological complications are increasingly seen in the emergency department. The knowledge of these associations will result in early diagnosis and treatment.


2020 ◽  
Vol 267 (9) ◽  
pp. 2492-2494 ◽  
Author(s):  
Nilo Riva ◽  
Tommaso Russo ◽  
Yuri Matteo Falzone ◽  
Marta Strollo ◽  
Stefano Amadio ◽  
...  

2017 ◽  
Vol 5 (2) ◽  
pp. 129-131
Author(s):  
Uzzwal Kumar Mallick ◽  
Badrul Alam ◽  
Mohammad Asaduzzaman

Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy. In typical cases, the first symptoms of GBS are pain, numbness, paresthesia, weakness in the limbs. Autonomic involvement is common and causes urinary retention and ileus. Most of these symptoms overlap with those of cervical myelopathy. Therefore, correct diagnosis of GBS in a patient with symptomatic cervical myelopathy or in a patient with atypical manifestations of GBS can be difficult, especially early in the course of GBS. We report a 60-year-old man who was admitted to the neurosurgery department with worsening neck pain, numbness and weakness in the hands initially thought to be secondary to progressive cervical myelopathy. However, his symptoms rapidly progressed to flaccid areflexic quadriparesis and respiratory difficulty within few days and shifted to ICU for ventilator support. Electrophysiological studies and cerebrospinal fluid analysis were consistent with an acquired demyelinating polyradiculoneuropathy. We planned for immunotherapy with intravenous immunoglobulin , but his condition was improving day by day with conservative treatment , so immunotherapy with intravenous immunoglobulin was not initiated. Any patient presenting as unexplain Cervical myelopathy, GBS should be kept in mind before planning any surgical intervention.Bangladesh Crit Care J September 2017; 5(2): 129-131


2016 ◽  
Vol 21 (4) ◽  
Author(s):  
Christopher J Williams ◽  
Rhys H Thomas ◽  
Trevor P Pickersgill ◽  
Marion Lyons ◽  
Gwen Lowe ◽  
...  

We report a cluster of atypical Guillain–Barré syndrome in 10 adults temporally related to a cluster of four children with acute flaccid paralysis, over a 3-month period in South Wales, United Kingdom. All adult cases were male, aged between 24 and 77 years. Seven had prominent facial diplegia at onset. Available electrophysiological studies showed axonal involvement in five adults. Seven reported various forms of respiratory disease before onset of neurological symptoms. The ages of children ranged from one to 13 years, three of the four were two years old or younger. Enterovirus testing is available for three children; two had evidence of enterovirus D68 infection in stool or respiratory samples. We describe the clinical features, epidemiology and state of current investigations for these unusual clusters of illness.


2021 ◽  
pp. 1-5
Author(s):  
Walaa A. Kamel ◽  
Ismail Ibrahim Ismail ◽  
Jasem Yousef Al-Hashel

Objective: Guillain-Barré syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy that is often related to a previous infectious exposure. GBS emerged as a potentially serious complication of coronavirus disease 2019 (COVID-19) since its declaration as a global pandemic. We report the first case from Kuwait, to the best of our knowledge. Clinical Presentation: A 72-year-old male presented with 3 weeks history of acute progressive and ascending lower limbs weakness. He developed these symptoms 3 weeks after testing positive to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Electrophysiological studies showed acute demyelinating polyradiculoneuropathy and cerebrospinal fluid showed protein-cell dissociation. He was successfully treated with intravenous immunoglobulins (IVIGs). Conclusion: Neurologists should be aware of GBS as a potentially serious complication associated with CO­VID-19. Our patient had a favorable outcome with IVIG with no autonomic or respiratory affection.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Sedigheh Rafiei Tabatabaei ◽  
Ghazal Shariatpanahi ◽  
Romina Azadkiya ◽  
Parvaneh Karimzadeh ◽  
Abdollah Karimi

: Guillain-Barre syndrome (GBS) characterizes a monophasic ascending, symmetrical paralysis, with areflexia, progressing over days to weeks. Normally, as a post-infectious autoimmune procedure, it leads to destroying myelin. Scattered reports exist regarding the concurrent evidence of COVID-19 infection and adults with possible GBS. However, few former cases were reported in children. Here in, we report an 11 years-old boy with GBS concurrent with COVID-19 infection.


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