Therapeutic Effects of Combination of Proton Pump Inhibitor Administration and Vocal Training in Laryngopharyngeal Reflux Disease (LPRD) Patients with Both of Vocal Cord Inflammation and Muscle Tension Dysphonia

2012 ◽  
Vol 63 (2) ◽  
pp. 112-119
Author(s):  
Makoto Ogawa ◽  
Kiyohito Hosokawa ◽  
Hidenori Inohara
Keyword(s):  
Proton Pump Inhibitor ◽  
Vocal Cord ◽  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Muscle Tension ◽  
Therapeutic Effects ◽  
Muscle Tension Dysphonia ◽  
Vocal Training ◽  
Laryngopharyngeal Reflux Disease

A Randomized Clinical Trial of Proton Pump Inhibitors Combined with Traditional Chinese Medicine in the Treatment of Laryngopharyngeal Reflux Disease

2021 ◽  
Author(s):  
Feng Pei ◽  
Wei Jia Hu ◽  
Yi Nan Mao ◽  
Yu Liang Zhao
Keyword(s):  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Short Form ◽  
Therapeutic Effects ◽  
Reflux Symptom Index ◽  
Symptom Index ◽  
Laryngopharyngeal Reflux Disease ◽  
Group A ◽  
Group B

Background:To explore whether combined with TCM based on classical proton pumpinhibitors PPIs therapy can achieve better efficacy for patients withlaryngopharyngeal reflux disease. Methods: There were 150 laryngopharyngeal refluxpatients enrolled and divided into three groups randomly, with 50 cases in each group.Patients in group A were treated with the proton pump inhibitor (PPI) lansoprazole.Patients in group B were treated with lansoprazole combined with Banxia Houpudecoction, and patients in group C were treated with acupuncture treatments and acombination of Chinese and Western medicine. The reflux symptom index (RSI), refluxfinding score (RFS), and quality of life (36 item short form health survey questionnaire)were assessed before and 4 and 8 weeks after treatment. Results: The RSI and RFSscores of the three groups were significantly reduced after treatment (P < 0.001). Ingroup B and C, they were lower than in group A at 8 weeks (P < 0.01). The SF 36 scoreof 3 groups increased after treatment. At both 4 and 8 weeks (P < 0.001), and patientsin groups B and C scored higher than patients in group A (P < 0.001). The total effectiverate of group B and group C was higher than that of group A (P < 0.05). Conclusion:All three treatments have therapeutic effects on the disease, but the efficacy of a PPIalone is not as good as the combined treatments’ efficacies. Moreover, PPI combinedwith Banxia Houpu decoction and/or acupuncture treatment substantially affects lifeimprovement.

Comparison of Evaluation Scales for Trial Administration of Proton Pump Inhibitor for Suspected Laryngopharyngeal Reflux Disease

2012 ◽  
Vol 63 (2) ◽  
pp. 217-217
Author(s):  
K. Hosokawa ◽  
M. Ogawa ◽  
R. Mochiduki ◽  
T. Iwahashi ◽  
H. Sasai ◽  
...  
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Laryngopharyngeal Reflux Disease

Influence of Age on Treatment with Proton Pump Inhibitor in Patients with Laryngopharyngeal Reflux Disease

2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P207-P207
Author(s):  
Young-Chan Lee ◽  
Seung-Woo Kim ◽  
Kee-Hwan Kwon ◽  
Young Gyu Eun
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Laryngopharyngeal Reflux Disease

Comparative Evaluation and Management of Dysphonia Between Adults <65 and ≥65 Years of Age

2020 ◽  
pp. 019459982097843
Author(s):  
Amy Jacks ◽  
Hannah Kavookjian ◽  
Shannon Kraft
Keyword(s):  
Vocal Cord ◽  
Laryngopharyngeal Reflux ◽  
Tertiary Care ◽  
Muscle Tension ◽  
Voice Handicap Index ◽  
Voice Therapy ◽  
Old Patients ◽  
Presenting Symptoms ◽  
Muscle Tension Dysphonia ◽  
Significant Relationships

Objective To compare presenting symptoms, etiology, and treatment outcomes among dysphonic adults <65 and ≥65 years of age. Study Design Retrospective cohort study. Setting Tertiary care voice center between January 2011 and June 2016. Methods A total of 755 patients presenting for dysphonia were included in the study: 513 adults <65 years of age and 242 adults ≥65. Data collected included demographics, referral information, prior diagnoses, prior treatments, clinical examination findings, diagnosis, coexisting symptoms, treatments, and pre- and postintervention Voice Handicap Index scores. Statistical analysis was performed with SPSS to determine significant relationships between variables of interest. Results The most common etiologies of dysphonia were vocal cord atrophy (44.8%) in the ≥65 cohort and benign vocal cord lesions (17.8%) in the <65 cohort. When compared with adults <65 years old, patients ≥65 had a higher incidence of neurologic dysphonia ( P = .006) and vocal cord atrophy ( P < .001) but were less likely to have laryngopharyngeal reflux ( P = .001), benign vocal cord lesions ( P < .001), or muscle tension dysphonia ( P < .001). Overall, 139 patients had surgery, 251 received medical therapy, and 156 underwent voice therapy. The ≥65 cohort demonstrated improvement in Voice Handicap Index scores after surgery ( P = .001) and voice therapy ( P = .034), as did the <65 cohort (surgery, P < .001; voice therapy, P = .015). Adult surgical patients <65 reported greater improvements than patients ≥65 ( P = .021). Conclusions There are notable differences in the pathophysiology of dysphonia between patients aged ≥65 and <65 years. Although adults <65 reported slightly better outcomes with surgery, patients ≥65 obtained significant benefit from surgery and voice therapy.

Effects of Proton Pump Inhibitors in Patients with Laryngopharyngeal Reflux Disease

2011 ◽  
Vol 58 (110-111) ◽  
Author(s):  
Toshimi Chiba ◽  
Norihiko Kudara ◽  
Yukito Abiko ◽  
Masaki Endo ◽  
Kazuyuki Suzuki ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Laryngopharyngeal Reflux Disease

Weaning of proton pump inhibitors in patients with suspected laryngopharyngeal reflux disease

2017 ◽  
Vol 128 (1) ◽  
pp. 133-137 ◽  
Author(s):  
R. Jun Lin ◽  
Shaum Sridharan ◽  
Libby J. Smith ◽  
VyVy N. Young ◽  
Clark A. Rosen
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Laryngopharyngeal Reflux Disease
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